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4KDC
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BU of 4kdc by Molmil
Crystal Structure of UBIG
分子名称: 3-demethylubiquinone-9 3-methyltransferase
著者Zhu, Y, Teng, M, Li, X.
登録日2013-04-24
公開日2014-04-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins.
Biochem. J., 470, 2015
4I6Q
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BU of 4i6q by Molmil
JAK3 kinase domain in complex with 2-Phenoxy-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1-cyclopropyl-ethyl)-amide
分子名称: 1-phenylurea, N-[(1S)-1-cyclopropylethyl]-2-phenoxy-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase JAK3
著者Kuglstatter, A, Shao, A.
登録日2012-11-30
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
4HVD
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BU of 4hvd by Molmil
JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide
分子名称: 1-phenylurea, 2-cyclopropyl-N-[(2S)-3,3-dimethylbutan-2-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase JAK3
著者Kuglstatter, A, Shao, A.
登録日2012-11-06
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models.
J.Med.Chem., 56, 2013
7XQ5
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BU of 7xq5 by Molmil
Crystal structure of ScIno2p-ScIno4p bound promoter DNA
分子名称: DNA (5'-D(*GP*AP*TP*TP*TP*TP*CP*AP*CP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*GP*TP*GP*AP*AP*AP*AP*T)-3'), HEXANE-1,6-DIOL, ...
著者Khan, M.H, Lu, X.
登録日2022-05-06
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Analysis of Ino2p/Ino4p Mutual Interactions and Their Binding Interface with Promoter DNA.
Int J Mol Sci, 23, 2022
3FE5
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BU of 3fe5 by Molmil
Crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from bovine kidney
分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, FE (III) ION
著者Dilovic, I, Gliubich, F, Malpeli, G, Zanotti, G, Matkovic-Calogovic, D.
登録日2008-11-27
公開日2009-06-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structure of bovine 3-hydroxyanthranilate 3,4-dioxygenase.
Biopolymers, 2009
7W27
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BU of 7w27 by Molmil
Crystal structure of BEND3-BEN4-DNA complex
分子名称: BEN domain-containing protein 3, DNA (5'-D(P*GP*GP*AP*CP*CP*CP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*GP*CP*GP*TP*GP*GP*GP*TP*C)-3')
著者Zheng, L, Ren, A.
登録日2021-11-22
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins.
Genes Dev., 36, 2022
7V5Y
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BU of 7v5y by Molmil
Crystal structure of hexameric complex of Sa2YoeB-Sa2YefM toxin-antitoxin from Staphylococcus aureus
分子名称: Antitoxin, Putative mRNA interferase YoeB
著者Xue, L, Khan, M.H, Yue, J.
登録日2021-08-18
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
7V6W
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Crystal structure of heterohexameric Sa2YoeB-Sa2YefM complex bound to 26bp-DNA
分子名称: Antitoxin, DNA (25-MER), DNA (26-MER), ...
著者Xue, L, Khan, M.H, Yue, J.
登録日2021-08-20
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
7V5Z
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BU of 7v5z by Molmil
Crystal structure of heterotetrameric complex of Sa2YoeB-Sa2YefM toxin-antitoxin from Staphylococcus aureus
分子名称: Antitoxin, Putative mRNA interferase YoeB
著者Xue, L, Khan, M.H, Yue, J.
登録日2021-08-18
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
4IQ8
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BU of 4iq8 by Molmil
Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae
分子名称: Glyceraldehyde-3-phosphate dehydrogenase 3
著者Wang, H, Liu, Q, Niu, L, Teng, M, Li, X.
登録日2013-01-11
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Preliminary crystallographic analysis of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 68, 2012
2GG2
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BU of 2gg2 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: 5-IMINO-4-(3-TRIFLUOROMETHYL-PHENYLAZO)-5H-PYRAZOL-3-YLAMINE, COBALT (II) ION, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GG0
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BU of 2gg0 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: COBALT (II) ION, METHYL N-{(2S,3R)-3-AMINO-2-HYDROXY-3-[4-(TRIFLUOROMETHYL)PHENYL]PROPANOYL}ALANYLGLYCINATE, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GGB
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BU of 2ggb by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: COBALT (II) ION, METHYL N-[(2S,3R)-3-AMINO-2-HYDROXYHEPTANOYL]-L-SERYL-L-LEUCINATE, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GG8
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BU of 2gg8 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: COBALT (II) ION, METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GG7
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BU of 2gg7 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: 3-(5-AMINO-3-IMINO-3H-PYRAZOL-4-YLAZO)-BENZOIC ACID, COBALT (II) ION, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GG5
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BU of 2gg5 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: 5-IMINO-4-(2-TRIFLUOROMETHYL-PHENYLAZO)-5H-PYRAZOL-3-YLAMINE, COBALT (II) ION, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GG9
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BU of 2gg9 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: COBALT (II) ION, METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-ISOPROPYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GG3
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BU of 2gg3 by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: 4-(4-FLUORO-PHENYLAZO)-5-IMINO-5H-PYRAZOL-3-YLAMINE, COBALT (II) ION, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GGC
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BU of 2ggc by Molmil
Novel bacterial methionine aminopeptidase inhibitors
分子名称: COBALT (II) ION, METHIONINE, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
8FYM
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BU of 8fym by Molmil
Crystal structure of Fab235 in complex with MPER peptide
分子名称: ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ...
著者Tan, K, Kim, M, Reinherz, E.L.
登録日2023-01-26
公開日2023-10-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
8FWF
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BU of 8fwf by Molmil
Crystal structure of Apo form Fab235
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Tan, K, Kim, M, Reinherz, E.L.
登録日2023-01-21
公開日2023-10-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
8FXJ
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BU of 8fxj by Molmil
Crystal structure of Fab460
分子名称: ACETATE ION, CHLORIDE ION, Fab460, ...
著者Tan, K, Kim, M, Reinherz, E.L.
登録日2023-01-24
公開日2023-10-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
8FZ2
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Crystal structure of Fab460 in complex with MPER peptide
分子名称: Fab460, H chain, L chain, ...
著者Tan, K, Kim, M, Reinherz, E.L.
登録日2023-01-27
公開日2023-10-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023

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