8S5B
 
 | | Crystal structure of the sulfoquinovosyl binding protein (SmoF) from A. tumefaciens sulfo-SMO pathway in complex with SQOctyl ligand | | 分子名称: | Sulfoquinovosyl glycerol-binding protein SmoF, [(2~{S},3~{S},4~{S},5~{R},6~{S})-6-octoxy-3,4,5-tris(oxidanyl)oxan-2-yl]methanesulfonic acid | | 著者 | Snow, A.J.D, Sharma, M, Davies, G.J. | | 登録日 | 2024-02-23 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Capture-and-release of a sulfoquinovose-binding protein on sulfoquinovose-modified agarose.
Org.Biomol.Chem., 22, 2024
|
|
6E2M
 | | ASK1 kinase domain complex with inhibitor | | 分子名称: | Mitogen-activated protein kinase kinase kinase 5, N-[3-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide | | 著者 | Lansdon, E.B. | | 登録日 | 2018-07-11 | | 公開日 | 2018-09-19 | | 最終更新日 | 2018-10-17 | | 実験手法 | X-RAY DIFFRACTION (2.253 Å) | | 主引用文献 | ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J. Clin. Invest., 128, 2018
|
|
6E2N
 | | ASK1 kinase domain complex with inhibitor | | 分子名称: | Mitogen-activated protein kinase kinase kinase 5, N-[3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl][3,4'-bipyridine]-2'-carboxamide | | 著者 | Lansdon, E.B. | | 登録日 | 2018-07-11 | | 公開日 | 2018-09-19 | | 最終更新日 | 2018-10-17 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J. Clin. Invest., 128, 2018
|
|
6E2O
 | | ASK1 kinase domain complex with inhibitor | | 分子名称: | 4-(4-cyclopropyl-1H-imidazol-1-yl)-N-[3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide, Mitogen-activated protein kinase kinase kinase 5 | | 著者 | Lansdon, E.B. | | 登録日 | 2018-07-11 | | 公開日 | 2018-09-19 | | 最終更新日 | 2018-10-17 | | 実験手法 | X-RAY DIFFRACTION (2.389 Å) | | 主引用文献 | ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J. Clin. Invest., 128, 2018
|
|
4K91
 | | Crystal structure of Penicillin-Binding Protein 5 (PBP5) from Pseudomonas aeruginosa in apo state | | 分子名称: | D-ala-D-ala-carboxypeptidase, SUCCINIC ACID | | 著者 | Smith, J, Toth, M, Vakulenko, S, Mobashery, S, Chen, Y. | | 登録日 | 2013-04-19 | | 公開日 | 2013-09-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural analysis of the role of Pseudomonas aeruginosa penicillin-binding protein 5 in beta-lactam resistance.
Antimicrob.Agents Chemother., 57, 2013
|
|
8DA2
 | | Acinetobacter baumannii L,D-transpeptidase | | 分子名称: | L,D-transpeptidase family protein | | 著者 | Toth, M, Stewart, N.K, Smith, C.A, Vakulenko, S.B. | | 登録日 | 2022-06-12 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The l,d-Transpeptidase Ldt Ab from Acinetobacter baumannii Is Poorly Inhibited by Carbapenems and Has a Unique Structural Architecture.
Acs Infect Dis., 8, 2022
|
|
7LQV
 | | Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-8 Heavy Chain, 4-8 Light chain, ... | | 著者 | Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L. | | 登録日 | 2021-02-15 | | 公開日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite
Cell Host Microbe, 2021
|
|
7LQW
 | | Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike | | 分子名称: | 2-17 Heavy Chain, 2-17 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L. | | 登録日 | 2021-02-15 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (4.47 Å) | | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
|
|
5MMH
 | |
5XJG
 | | Crystal structure of Vac8p bound to Nvj1p | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Nucleus-vacuole junction protein 1, ... | | 著者 | Jeong, H, Park, J, Jun, Y, Lee, C. | | 登録日 | 2017-05-01 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
3TD5
 | | Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with L-Ala-gamma-D-Glu-m-DAP-D-Ala-D-Ala | | 分子名称: | CHLORIDE ION, Outer membrane protein omp38, peptide(L-Ala-gamma-D-Glu-m-DAP-D-Ala-D-Ala) | | 著者 | Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y. | | 登録日 | 2011-08-10 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
|
|
3TD4
 | | Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with diaminopimelate | | 分子名称: | 2,6-DIAMINOPIMELIC ACID, Outer membrane protein omp38 | | 著者 | Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y. | | 登録日 | 2011-08-10 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
|
|
3TD3
 | | Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with glycine | | 分子名称: | GLYCINE, Outer membrane protein omp38 | | 著者 | Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y. | | 登録日 | 2011-08-10 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
|
|
8DUA
 | | SIV E660.CR54 SOS-2P Env Trimer with ITS92.02 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ... | | 著者 | Gorman, J, Kwong, P.D. | | 登録日 | 2022-07-27 | | 公開日 | 2022-10-26 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | | 主引用文献 | Cryo-EM structures of prefusion SIV envelope trimer.
Nat.Struct.Mol.Biol., 29, 2022
|
|
8DVD
 | |
6R5R
 | |
6R5V
 | |
6R5T
 | |
8ELI
 | |
8EUW
 | |
8EUV
 | |
8EUU
 | | Cryo-EM structure of HIV-1 BG505 DS-SOSIP ENV trimer bound to VRC34.01 FAB | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | Pletnev, S, Kwong, P. | | 登録日 | 2022-10-19 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.
Nat Commun, 14, 2023
|
|
6R5N
 | |
6R5O
 | |
8F7Z
 | | VRC34.01_mm28 bound to fusion peptide | | 分子名称: | HIV-1 Env Fusion Peptide, VRC34_m228 Light Chain, VRC34_mm28 Heavy Chain | | 著者 | Olia, A.S, Kwong, P.D. | | 登録日 | 2022-11-21 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.
Nat Commun, 14, 2023
|
|
