7DEH
 
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2VJ2
 | | Human Jagged-1, domains DSL and EGFs1-3 | | 分子名称: | D-MALATE, JAGGED-1 | | 著者 | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Handford, P.A, Lea, S.M. | | 登録日 | 2007-12-06 | | 公開日 | 2008-07-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
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2PCK
 | | Crystal structure of PH0725 from Pyrococcus horikoshii OT3 | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase | | 著者 | Yamamoto, H, Morikawa, Y, Matsuura, Y, Shimada, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-30 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
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2P6I
 | | Crystal structure of PH0725 from Pyrococcus horikoshii OT3 | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase | | 著者 | Yamamoto, H, Matsuura, Y, Morikawa, Y, Shimada, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-18 | | 公開日 | 2007-09-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
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2VJ3
 | | Human Notch-1 EGFs 11-13 | | 分子名称: | CALCIUM ION, CHLORIDE ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ... | | 著者 | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Lea, S.M. | | 登録日 | 2007-12-06 | | 公開日 | 2008-07-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
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3WC6
 | | Carboxypeptidase B in complex with 2nd zinc | | 分子名称: | ACETATE ION, Carboxypeptidase B, ZINC ION | | 著者 | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | | 登録日 | 2013-05-24 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme.
J.Med.Chem., 56, 2013
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5WIR
 | | Structure of the TRF1-TERB1 interface | | 分子名称: | TERB1-TBM, Telomeric repeat-binding factor 1 | | 著者 | Nandakumar, J, Pendlebury, D.F, Smith, E.M, Tesmer, V.M. | | 登録日 | 2017-07-20 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dissecting the telomere-inner nuclear membrane interface formed in meiosis.
Nat. Struct. Mol. Biol., 24, 2017
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2P6L
 | | Crystal structure of PH0725 from Pyrococcus horikoshii OT3 | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase | | 著者 | Yamamoto, H, Matsuura, Y, Ono, N, Shimada, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-19 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
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1RLS
 | | CRYSTAL STRUCTURE OF RNASE T1 COMPLEXED WITH THE PRODUCT NUCLEOTIDE 3'-GMP. STRUCTURAL EVIDENCE FOR DIRECT INTERACTION OF HISTIDINE 40 AND GLUTAMIC ACID 58 WITH THE 2'-HYDROXYL GROUP OF RIBOSE | | 分子名称: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | | 著者 | Gohda, K, Oka, K.-I, Tomita, K.-I, Hakoshima, T. | | 登録日 | 1994-03-29 | | 公開日 | 1994-12-20 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of RNase T1 complexed with the product nucleotide 3'-GMP. Structural evidence for direct interaction of histidine 40 and glutamic acid 58 with the 2'-hydroxyl group of the ribose.
J.Biol.Chem., 269, 1994
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3WIA
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3WI9
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7CAO
 | | Crystal structure of red chromoprotein from Olindias formosa | | 分子名称: | Chromoprotein | | 著者 | Nakashima, R, Zhai, L, Ike, Y, Matsudz, T, Nagai, T. | | 登録日 | 2020-06-09 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-based analysis and evolution of a monomerized red-colored chromoprotein from the Olindias formosa jellyfish.
Protein Sci., 31, 2022
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7DCF
 | | Crystal structure of EHMT2 SET domain in complex with compound 10 | | 分子名称: | 5'-methoxy-6'-(1-methyl-2,3,4,7-tetrahydroazepin-5-yl)spiro[cyclobutane-1,3'-indole]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... | | 著者 | Suzuki, M, Katayama, K. | | 登録日 | 2020-10-26 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of DS79932728: A Potent, Orally Available G9a/GLP Inhibitor for Treating beta-Thalassemia and Sickle Cell Disease.
Acs Med.Chem.Lett., 12, 2021
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2I3H
 | | Structure of an ML-IAP/XIAP chimera bound to a 4-mer peptide (AVPW) | | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AVPW peptide, ... | | 著者 | Fairbrother, W.J, Franklin, M.C. | | 登録日 | 2006-08-18 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Acs Chem.Biol., 1, 2006
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2I3I
 | | Structure of an ML-IAP/XIAP chimera bound to a peptidomimetic | | 分子名称: | (3R,6R,9AR)-2,2-DIMETHYL-6-[(N-METHYL-L-ALANYL)AMINO]-N-(3-METHYL-1-PHENYL-1H-PYRAZOL-5-YL)-5-OXO-2,3,5,6,9,9A-HEXAHYDRO[1,3]THIAZOLO[3,2-A]AZEPINE-3-CARBOXAMIDE, 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Fairbrother, W.J, Franklin, M.C. | | 登録日 | 2006-08-18 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Acs Chem.Biol., 1, 2006
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5ZO9
 | | Eg5 motor domain in complex with STLC-type inhibitor PVEI0021 (C2 type) | | 分子名称: | (2R)-2-azanyl-3-[(4-methoxyphenyl)-diphenyl-methyl]sulfanyl-propanoic acid, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | | 著者 | Yokoyama, H, Sato, K. | | 登録日 | 2018-04-12 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors.
Acs Omega, 3, 2018
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5ZO8
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7WKZ
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5B1J
 | | Crystal structure of the electron-transfer complex of copper nitrite reductase with a cupredoxin | | 分子名称: | Blue copper protein, COPPER (II) ION, Copper-containing nitrite reductase | | 著者 | Nojiri, M, Koteishi, H, Yoneda, R, Hira, D. | | 登録日 | 2015-12-04 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and Function of Copper Nitrite Reductase
Metalloenzymes in denitrification: Applications and Environmental impacts, 2016
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5XDF
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4M9E
 | | Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA | | 分子名称: | ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... | | 著者 | Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X. | | 登録日 | 2013-08-14 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | Structural basis for Klf4 recognition of methylated DNA.
Nucleic Acids Res., 42, 2014
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5Z5E
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5Z7Y
 | | Crystal structure of Striga hermonthica HTL7 (ShHTL7) | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, Hyposensitive to light 7, ... | | 著者 | Xu, Y, Miyakawa, T, Nakamura, A, Tanokura, M. | | 登録日 | 2018-01-30 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga.
Nat Commun, 9, 2018
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5Z7Z
 | | Crystal structure of Striga hermonthica Dwarf14 (ShD14) | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dwarf 14, ... | | 著者 | Xu, Y, Miyakawa, T, Nakamura, A, Tanokura, M. | | 登録日 | 2018-01-30 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.978 Å) | | 主引用文献 | Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga.
Nat Commun, 9, 2018
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4K2Y
 | | Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-chloro-1,3-dihydro-2H-indol-2-one | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-1,3-dihydro-2H-indol-2-one, Chymase, ... | | 著者 | Collins, B.K, Padyana, A.K. | | 登録日 | 2013-04-09 | | 公開日 | 2013-05-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies.
J.Med.Chem., 56, 2013
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