7WKZ
Crystal structure of the HSA complex with mycophenolate and aripiprazole
Summary for 7WKZ
Entry DOI | 10.2210/pdb7wkz/pdb |
Descriptor | Serum albumin, 7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one, MYCOPHENOLIC ACID (3 entities in total) |
Functional Keywords | drug, complex, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 134679.88 |
Authors | Kawai, A.,Yamasaki, K. (deposition date: 2022-01-12, release date: 2022-12-28, Last modification date: 2023-11-29) |
Primary citation | Yamasaki, K.,Teshima, H.,Yukizawa, R.,Kuyama, K.,Tsukigawa, K.,Nishi, K.,Otagiri, M.,Kawai, A. Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure. J.Med.Chem., 66:951-961, 2023 Cited by PubMed: 36538495DOI: 10.1021/acs.jmedchem.2c01790 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.992 Å) |
Structure validation
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