7WVO
 
 | | SARS-CoV-2 Omicron S-open-2 | | 分子名称: | Spike glycoprotein | | 著者 | Li, J.W, Cong, Y. | | 登録日 | 2022-02-10 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron.
Nature, 604, 2022
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7WVN
 | | SARS-CoV-2 Omicron S-open | | 分子名称: | Spike glycoprotein | | 著者 | Li, J.W, Cong, Y. | | 登録日 | 2022-02-10 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron.
Nature, 604, 2022
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7ELY
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7E1L
 | | Crystal structure of apo form PhlH | | 分子名称: | DUF1956 domain-containing protein | | 著者 | Zhang, N, Wu, J, He, Y.X, Ge, H. | | 登録日 | 2021-02-01 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules.
J.Biol.Chem., 298, 2022
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7E1N
 | | Crystal structure of PhlH in complex with 2,4-diacetylphloroglucinol | | 分子名称: | 2,4-bis[(1R)-1-oxidanylethyl]benzene-1,3,5-triol, DUF1956 domain-containing protein | | 著者 | Zhang, N, Wu, J, He, Y.X, Ge, H. | | 登録日 | 2021-02-02 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules.
J.Biol.Chem., 298, 2022
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4M5B
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7JG3
 | | Human GAR transformylase in complex with GAR substrate and AGF103 inhibitor | | 分子名称: | GLYCINAMIDE RIBONUCLEOTIDE, N-{5-[4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]furan-2-carbonyl}-L-glutamic acid, SODIUM ION, ... | | 著者 | Wong-Roushar, J, Dann III, C.E. | | 登録日 | 2020-07-18 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | | 主引用文献 | Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors
Bioorg.Med.Chem., 37, 2021
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7JG4
 | | Human GAR transformylase in complex with GAR substrate and AGF131 inhibitor | | 分子名称: | GLYCINAMIDE RIBONUCLEOTIDE, N-(5-{3-[(1S,7R,8R,9S)-4-amino-2-oxo-7lambda~4~-thia-3,5-diazatetracyclo[4.3.0.0~1,7~.0~7,9~]nona-3,5-dien-8-yl]propyl}thiophene-2-carbonyl)-L-glutamic acid, SODIUM ION, ... | | 著者 | Wong-Roushar, J, Dann III, C.E. | | 登録日 | 2020-07-18 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.455 Å) | | 主引用文献 | Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors
Bioorg.Med.Chem., 37, 2021
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7JG0
 | | Human GAR transformylase in complex with GAR substrate and AGF102 inhibitor | | 分子名称: | GLYCINAMIDE RIBONUCLEOTIDE, N-{5-[4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]thiophene-2-carbonyl}-L-glutamic acid, Trifunctional purine biosynthetic protein adenosine-3 | | 著者 | Wong-Roushar, J, Dann III, C.E. | | 登録日 | 2020-07-18 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.984 Å) | | 主引用文献 | Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors
Bioorg.Med.Chem., 37, 2021
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7XZO
 | | Formate-tetrahydrofolate ligase in complex with ATP | | 分子名称: | (R,R)-2,3-BUTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Formate--tetrahydrofolate ligase, ... | | 著者 | Fang, C.L, Zhang, Y. | | 登録日 | 2022-06-03 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Identification of FtfL as a novel target of berberine in intestinal bacteria.
Bmc Biol., 21, 2023
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7XZN
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7XZP
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5W4W
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2IIE
 | | single chain Integration Host Factor protein (scIHF2) in complex with DNA | | 分子名称: | DNA (5'-D(*DGP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DCP*DAP*DAP*DAP*DAP*DAP*DAP*DGP*DCP*DAP*DTP*DT)-3'), Integration host factor, ... | | 著者 | Bao, Q, Droege, P, Davey, C.A. | | 登録日 | 2006-09-28 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | A Divalent Metal-mediated Switch Controlling Protein-induced DNA Bending
J.Mol.Biol., 367, 2007
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6A8O
 | | Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor mupain-1-16 | | 分子名称: | Plasma kallikrein, alpha-D-mannopyranose, peptide inhibitor,, ... | | 著者 | Xu, M, Jiang, L, Huang, M. | | 登録日 | 2018-07-09 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Crystal structure of plasma kallikrein reveals the unusual flexibility of the S1 pocket triggered by Glu217.
Febs Lett., 592, 2018
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2IIF
 | | single chain Integration Host Factor mutant protein (scIHF2-K45aE) in complex with DNA | | 分子名称: | DNA (5'-D(*DGP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DCP*DAP*DAP*DAP*DAP*DAP*DAP*DGP*DCP*DAP*DTP*DT)-3'), Integration host factor, ... | | 著者 | Bao, Q, Droege, P, Davey, C.A. | | 登録日 | 2006-09-28 | | 公開日 | 2007-02-20 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | A Divalent Metal-mediated Switch Controlling Protein-induced DNA Bending
J.Mol.Biol., 367, 2007
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3POA
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3PO8
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8INP
 | | A reversible glycosyltransferase of tectorigenin - Bc7OUGT | | 分子名称: | Bc7OUGT, URIDINE-5'-DIPHOSPHATE, beta-D-glucopyranose | | 著者 | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | | 登録日 | 2023-03-10 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence.
Plant Biotechnol J, 21, 2023
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8ITA
 | | A reversible glycosyltransferase of tectorigenin - Bc7OUGT complexed with UDP and tectorigenin | | 分子名称: | 3-(4-hydroxyphenyl)-6-methoxy-5,7-bis(oxidanyl)chromen-4-one, Bc7OUGT, URIDINE-5'-DIPHOSPHATE | | 著者 | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | | 登録日 | 2023-03-22 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence.
Plant Biotechnol J, 21, 2023
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3QK9
 | | Yeast Tim44 C-terminal domain complexed with Cymal-3 | | 分子名称: | CHLORIDE ION, Mitochondrial import inner membrane translocase subunit TIM44 | | 著者 | Cui, W, Josyula, R, Fu, Z, Sha, B. | | 登録日 | 2011-01-31 | | 公開日 | 2011-03-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Membrane Binding Mechanism of Yeast Mitochondrial Peripheral Membrane Protein TIM44.
Protein Pept.Lett., 18, 2011
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3QD2
 | | Crystal structure of mouse PERK kinase domain | | 分子名称: | Eukaryotic translation initiation factor 2-alpha kinase 3 | | 著者 | Wenjun, C, Jingzhi, L, David, R, Bingdong, S. | | 登録日 | 2011-01-17 | | 公開日 | 2011-04-27 | | 最終更新日 | 2019-01-16 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The structure of the PERK kinase domain suggests the mechanism for its activation.
Acta Crystallogr.,Sect.D, 67, 2011
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1DSS
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1IHY
 | | GAPDH complexed with ADP-ribose | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, SULFATE ION | | 著者 | Shen, Y.-Q, Song, S.-Y, Lin, Z.-J. | | 登録日 | 2001-04-20 | | 公開日 | 2002-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of D-glyceraldehyde-3-phosphate dehydrogenase complexed with coenzyme analogues.
Acta Crystallogr.,Sect.D, 58, 2002
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6IS9
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