7U2F
 
 | | G116F Pseudomonas aeruginosa azurin | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, COPPER (II) ION | | 著者 | Liu, Y, Lu, Y. | | 登録日 | 2022-02-23 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin.
Inorg.Chem., 62, 2023
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5GMR
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7U0D
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5AZB
 | | Crystal structure of Escherichia coli Lgt in complex with phosphatidylglycerol and the inhibitor palmitic acid | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PALMITIC ACID, Prolipoprotein diacylglyceryl transferase, ... | | 著者 | Zhang, X.C, Mao, G, Zhao, Y. | | 登録日 | 2015-09-30 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of E. coli lipoprotein diacylglyceryl transferase
Nat Commun, 7, 2016
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1P9G
 | | Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Ecommia ulmoides Oliver at atomic resolution | | 分子名称: | ACETATE ION, EAFP 2 | | 著者 | Xiang, Y, Huang, R.H, Liu, X.Z, Wang, D.C. | | 登録日 | 2003-05-12 | | 公開日 | 2004-06-01 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (0.84 Å) | | 主引用文献 | Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Eucommia ulmoides Oliver at an atomic resolution.
J.Struct.Biol., 148, 2004
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2EWG
 | | T. brucei Farnesyl Diphosphate Synthase Complexed with Minodronate | | 分子名称: | (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), MAGNESIUM ION, S-1,2-PROPANEDIOL, ... | | 著者 | Cao, R, Mao, J, Gao, Y, Robinson, H, Odeh, S, Goddard, A, Oldfield, E. | | 登録日 | 2005-11-03 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes.
J.Am.Chem.Soc., 128, 2006
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3EFK
 | | Structure of c-Met with pyrimidone inhibitor 50 | | 分子名称: | 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3H)-one, Hepatocyte growth factor receptor | | 著者 | Bellon, S.F, D'Angelo, N, Whittington, D, Dussault, I. | | 登録日 | 2008-09-09 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of potent c-Met inhibitors.
J.Med.Chem., 51, 2008
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3EFJ
 | | Structure of c-Met with pyrimidone inhibitor 7 | | 分子名称: | 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one, Hepatocyte growth factor receptor | | 著者 | D'Angelo, N, Bellon, S, Whittington, D. | | 登録日 | 2008-09-09 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of potent c-Met inhibitors.
J.Med.Chem., 51, 2008
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2L5P
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7YDY
 | | SARS-CoV-2 Spike (6P) in complex with 1 R1-32 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | 登録日 | 2022-07-04 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (4.75 Å) | | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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7YEG
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | 登録日 | 2022-07-05 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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7YDI
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32, Light chain of R1-32, ... | | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | 登録日 | 2022-07-04 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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7BI9
 | | PI3KC2a core in complex with PIK90 | | 分子名称: | 1,2-ETHANEDIOL, N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
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7BI6
 | | PI3KC2a core in complex with ATP | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
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7BI4
 | | PI3KC2a core apo | | 分子名称: | 1,2-ETHANEDIOL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, SULFATE ION | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
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7BI2
 | | PI3KC2aDeltaN and DeltaC-C2 | | 分子名称: | 1,2-ETHANEDIOL, 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one, IODIDE ION, ... | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
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7YE5
 | | SARS-CoV-2 Spike (6P) in complex with 2 R1-32 Fabs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | 登録日 | 2022-07-05 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (6.75 Å) | | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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6TY9
 | | In situ structure of BmCPV RNA dependent RNA polymerase at initiation state | | 分子名称: | MAGNESIUM ION, Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), RNA-dependent RNA Polymerase, ... | | 著者 | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | | 登録日 | 2019-08-08 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019
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6TZ1
 | | In situ structure of BmCPV RNA-dependent RNA polymerase at early-elongation state | | 分子名称: | Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*A)-3'), RNA-dependent RNA Polymerase, Template RNA (5'-R(P*AP*GP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | | 著者 | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | | 登録日 | 2019-08-09 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019
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6TY8
 | | In situ structure of BmCPV RNA dependent RNA polymerase at quiescent state | | 分子名称: | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-dependent RNA Polymerase, Viral structural protein 4 | | 著者 | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | | 登録日 | 2019-08-08 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019
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6TZ2
 | | In situ structure of BmCPV RNA-dependent RNA polymerase at elongation state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-template RNA (36-MER), ... | | 著者 | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | | 登録日 | 2019-08-09 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019
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5ZXL
 | | Structure of GldA from E.coli | | 分子名称: | CHLORIDE ION, GLYCEROL, Glycerol dehydrogenase, ... | | 著者 | Zhang, J, Lin, L. | | 登録日 | 2018-05-21 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Structure of glycerol dehydrogenase (GldA) from Escherichia coli.
Acta Crystallogr F Struct Biol Commun, 75, 2019
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6TZ0
 | | In situ structure of BmCPV RNA-dependent RNA polymerase at abortive state | | 分子名称: | RNA-dependent RNA Polymerase, Viral structural protein 4 | | 著者 | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | | 登録日 | 2019-08-09 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019
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3NB7
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5J8V
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