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7WPH
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BU of 7wph by Molmil
SARS-CoV2 RBD bound to Fab06
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB06 light chain, Fab06 heavy chain, ...
著者Lin, J.Q, El Sahili, A, Lescar, J.
登録日2022-01-23
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Nat Commun, 13, 2022
7WPV
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BU of 7wpv by Molmil
Fab14 - a SARS-CoV2 RBD neutralising antibody
分子名称: Fab14 heavy chain, Fab14 light chain
著者Lin, J.Q, El Sahili, A, Lescar, J.
登録日2022-01-24
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Nat Commun, 13, 2022
6BHI
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BU of 6bhi by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6BHD
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BU of 6bhd by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SODIUM ION, ...
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6BHH
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BU of 6bhh by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SULFATE ION, ...
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-11-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6BHE
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BU of 6bhe by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
7WJM
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BU of 7wjm by Molmil
CryoEM structure of chitin synthase 1 from Phytophthora sojae
分子名称: Chitin synthase
著者Chen, W, Cao, P, Gong, Y, Yang, Q.
登録日2022-01-07
公開日2022-09-28
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for directional chitin biosynthesis.
Nature, 610, 2022
7WJN
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BU of 7wjn by Molmil
CryoEM structure of chitin synthase 1 mutant E495A from Phytophthora sojae complexed with UDP-GlcNAc
分子名称: Chitin synthase, MANGANESE (II) ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Chen, W, Cao, P, Gong, Y, Yang, Q.
登録日2022-01-07
公開日2022-09-28
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for directional chitin biosynthesis.
Nature, 610, 2022
7WJO
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CryoEM structure of chitin synthase 1 from Phytophthora sojae complexed with nikkomycin Z
分子名称: (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid (non-preferred name), Chitin synthase
著者Chen, W, Cao, P, Gong, Y, Yang, Q.
登録日2022-01-07
公開日2022-09-28
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for directional chitin biosynthesis.
Nature, 610, 2022
7EN6
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BU of 7en6 by Molmil
The crystal structure of Escherichia coli MurR in apo form
分子名称: HTH-type transcriptional regulator MurR, PHOSPHATE ION
著者Zhang, Y, Chen, W, Ji, Q.
登録日2021-04-16
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.276 Å)
主引用文献Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
7EN5
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BU of 7en5 by Molmil
The crystal structure of Escherichia coli MurR in complex with N-acetylglucosamine-6-phosphate
分子名称: 2-METHOXYETHANOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, GLYCEROL, ...
著者Zhang, Y, Chen, W, Ji, Q.
登録日2021-04-16
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
7EN7
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BU of 7en7 by Molmil
The crystal structure of Escherichia coli MurR in complex with N-acetylmuramic-acid-6-phosphate
分子名称: (2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, HTH-type transcriptional regulator MurR
著者Zhang, Y, Chen, W, Ji, Q.
登録日2021-04-16
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
7BU9
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BU of 7bu9 by Molmil
Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex
分子名称: H3(K4me3-K9me2) peptide, Spindlin-1
著者Zhao, F, Li, H.
登録日2020-04-05
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.502 Å)
主引用文献Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
J.Biol.Chem., 295, 2020
7BQZ
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BU of 7bqz by Molmil
Crystal Structure of Spindlin1 bound to H3(K4me3-K9me3) peptide
分子名称: H3(K4me3-K9me3) peptide, Spindlin-1
著者Zhao, F, Li, H.
登録日2020-03-26
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
J.Biol.Chem., 295, 2020
7BTD
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BU of 7btd by Molmil
Crystal structure of Rheb Y35N mutant bound to GppNHp
分子名称: GTP-binding protein Rheb, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-04-01
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020
7CPC
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BU of 7cpc by Molmil
His-Mediated Reversible Self-assembly of Ferritin Nanocage with Ni binding
分子名称: FE (III) ION, Ferritin, NICKEL (II) ION
著者Gu, C, Zhang, T, Zhao, G.
登録日2020-08-06
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献His-Mediated Reversible Self-Assembly of Ferritin Nanocages through Two Different Switches for Encapsulation of Cargo Molecules.
Acs Nano, 2020
7CPI
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BU of 7cpi by Molmil
His-Mediated Reversible Self-assembly of Ferritin Nanocage with Zn binding
分子名称: FE (III) ION, Ferritin, ZINC ION
著者Gu, C, Zhang, T, Zhao, G.
登録日2020-08-07
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献His-Mediated Reversible Self-Assembly of Ferritin Nanocages through Two Different Switches for Encapsulation of Cargo Molecules.
Acs Nano, 2020
7DCN
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BU of 7dcn by Molmil
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
分子名称: Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, SULFATE ION, ZINC ION
著者Xu, H, Wang, B, Su, X.D.
登録日2020-10-26
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Co-evolution-based prediction of metal-binding sites in proteomes by machine learning.
Nat.Chem.Biol., 19, 2023
7DCM
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BU of 7dcm by Molmil
Crystal structure of CITX
分子名称: Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, ZINC ION
著者Xu, H, Wang, B, Su, X.D.
登録日2020-10-26
公開日2021-11-03
最終更新日2023-05-17
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献Co-evolution-based prediction of metal-binding sites in proteomes by machine learning.
Nat.Chem.Biol., 19, 2023
7DNR
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BU of 7dnr by Molmil
Crystal Structure of Zn-bound SIS Domain of Glucosamine-6-P Synthase from E. coli
分子名称: Glutamine--fructose-6-phosphate aminotransferase [isomerizing], ZINC ION
著者Gao, C, Xiao, J.
登録日2020-12-10
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of Metal-binding Proteins by Thermal Proteome Profiling
To Be Published
7E5C
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BU of 7e5c by Molmil
Bacterial prolidase mutant D45W/L225Y/H226L/H343I
分子名称: MANGANESE (II) ION, Xaa-Pro dipeptidase
著者Yang, J.
登録日2021-02-18
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structure-based redesign of the bacterial prolidase active-site pocket for efficient enhancement of methyl-parathion hydrolysis
Catalysis Science And Technology, 11, 2021
7DWB
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BU of 7dwb by Molmil
Human Pannexin1 model
分子名称: Pannexin-1
著者Zhang, S.S, Yang, M.J.
登録日2021-01-17
公開日2021-05-26
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis.
Cell Discov, 7, 2021
7DX4
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BU of 7dx4 by Molmil
The structure of FC08 Fab-hA.CE2-RBD complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Heavy chain of FC08 Fab, ...
著者Cao, L, Wang, X.
登録日2021-01-18
公開日2021-04-21
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2.
Natl Sci Rev, 8, 2021
7D4G
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BU of 7d4g by Molmil
A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2
分子名称: Heavy chain of FC05 Fab, Light chain of FC05 Fab, Spike glycoprotein S1
著者Cao, L, Wang, X.
登録日2020-09-23
公開日2021-04-07
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2.
Natl Sci Rev, 8, 2021
7BTA
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BU of 7bta by Molmil
Crystal structure of Rheb D60K mutant bound to GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-03-31
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020

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