5ZKQ
| Crystal structure of the human platelet-activating factor receptor in complex with ABT-491 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-ethynyl-3-{3-fluoro-4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]benzene-1-carbonyl}-N,N-dimethyl-1H-indole-1-carboxamide, Platelet-activating factor receptor,Endolysin,Endolysin,Platelet-activating factor receptor, ... | 著者 | Cao, C, Zhao, Q, Zhang, X.C, Wu, B. | 登録日 | 2018-03-25 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for signal recognition and transduction by platelet-activating-factor receptor. Nat. Struct. Mol. Biol., 25, 2018
|
|
5ZKP
| Crystal structure of the human platelet-activating factor receptor in complex with SR 27417 | 分子名称: | FLAVIN MONONUCLEOTIDE, N1,N1-dimethyl-N2-[(pyridin-3-yl)methyl]-N2-{4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl}ethane-1,2-diamine, Platelet-activating factor receptor,Flavodoxin,Platelet-activating factor receptor | 著者 | Cao, C, Zhao, Q, Zhang, X.C, Wu, B. | 登録日 | 2018-03-25 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural basis for signal recognition and transduction by platelet-activating-factor receptor. Nat. Struct. Mol. Biol., 25, 2018
|
|
7WU4
| Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGi | 分子名称: | Adhesion G-protein coupled receptor F1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
|
|
7WU5
| Cryo-EM structure of the adhesion GPCR ADGRF1(H565A/T567A) in complex with miniGi | 分子名称: | Adhesion G-protein coupled receptor F1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
|
|
7WU3
| Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGs | 分子名称: | Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
|
|
7WU2
| Cryo-EM structure of the adhesion GPCR ADGRD1 in complex with miniGs | 分子名称: | Adhesion G-protein coupled receptor D1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2022-02-05 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604, 2022
|
|
4HVY
| A thermostable variant of human NUDT18 NUDIX domain obtained by Hot Colony Filtration | 分子名称: | GLYCEROL, MAGNESIUM ION, Nucleoside diphosphate-linked moiety X motif 18, ... | 著者 | Asial, I, Cheng, Y.X, Engman, H, Wu, B, Dollhopf, M, Nordlund, P, Cornvik, T. | 登録日 | 2012-11-07 | 公開日 | 2014-01-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell. Nat Commun, 4, 2013
|
|
4I7B
| Siah1 bound to synthetic peptide (ACE)KLRPV(ABA)MVRPTVR | 分子名称: | E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ZINC ION | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | 登録日 | 2012-11-30 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-based design of covalent siah inhibitors. Chem.Biol., 20, 2013
|
|
4I7C
| Siah1 mutant bound to synthetic peptide (ACE)KLRPV(23P)MVRPWVR | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ... | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | 登録日 | 2012-11-30 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of covalent siah inhibitors. Chem.Biol., 20, 2013
|
|
4I7D
| Siah1 bound to synthetic peptide (ACE)KLRPVAMVRP(PRK)VR | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ... | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | 登録日 | 2012-11-30 | 公開日 | 2013-08-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design of covalent siah inhibitors. Chem.Biol., 20, 2013
|
|
2JRJ
| Solution structure of the human Pirh2 RING-H2 domain. Northeast Structural Genomics Consortium Target HT2B | 分子名称: | Ring finger and CHY zinc finger domain containing protein 1, ZINC ION | 著者 | Sheng, Y, Lemak, A, Laister, R.C, Wu, B, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-06-27 | 公開日 | 2007-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis of Pirh2-mediated p53 ubiquitylation. Nat.Struct.Mol.Biol., 15, 2008
|
|
2KK4
| Solution NMR structure of protein AF2094 from Archaeoglobus fulgidus. Northeast Structural Genomics Consotium (NESG) target GT2 | 分子名称: | Uncharacterized protein AF_2094 | 著者 | Lemak, A, Yee, A, Wu, B, Karra, M, Ramelot, T, Fares, C, Semesi, A, Kennedy, M, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-15 | 公開日 | 2009-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of proterin AF2094 from Archaeoglobus fulgidus To be Published
|
|
2KP7
| Solution NMR structure of the Mus81 N-terminal HhH. Northeast Structural Genomics Consortium target MmT1A | 分子名称: | Crossover junction endonuclease MUS81 | 著者 | Laister, R.C, Wu, B, Lemak, A, Montelione, G.T, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-07 | 公開日 | 2010-01-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure and DNA binding mode of the Mus81 n-terminal helix-hairpin-helix domain To be Published
|
|
2LSM
| Solution structure of gpFI C-terminal domain | 分子名称: | DNA-packaging protein FI | 著者 | Popovic, A, Wu, B, Edwards, A.M, Davidson, A.R, Maxwell, K.L. | 登録日 | 2012-05-02 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and biochemical characterization of phage lambda FI protein (gpFI) reveals a novel mechanism of DNA packaging chaperone activity. J.Biol.Chem., 287, 2012
|
|
2KZR
| Solution NMR Structure of Ubiquitin thioesterase OTU1 (EC 3.1.2.-) from Mus musculus, Northeast Structural Genomics Consortium Target MmT2A | 分子名称: | Ubiquitin thioesterase OTU1 | 著者 | Chitayat, S, Gutmanas, A, Lemak, A, Yee, A, Bezsonova, I, Wu, B, Doherty, R.S, Semesi, A, Montelione, G.T, Arrowsmith, C.H, Dhe-Paganon, S, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-06-23 | 公開日 | 2010-07-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Northeast Structural Genomics Consortium Target MmT2A To be Published
|
|
2M2J
| Solution NMR structure of the N-terminal domain of STM1478 from Salmonella typhimurium LT2: Target STR147A of the Northeast Structural Genomics consortium (NESG), and APC101565 of the Midwest Center for Structural Genomics (MCSG). | 分子名称: | Putative periplasmic protein | 著者 | Houliston, S, Yee, A, Lemak, A, Garcia, M, Wu, B, Savchenko, A, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2012-12-21 | 公開日 | 2013-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO. Plos One, 9, 2014
|
|
6J20
| Crystal structure of the human NK1 substance P receptor | 分子名称: | 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin | 著者 | Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q. | 登録日 | 2018-12-30 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography. Nat Commun, 10, 2019
|
|
6J21
| Crystal structure of the human NK1 substance P receptor | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin | 著者 | Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q. | 登録日 | 2018-12-30 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography. Nat Commun, 10, 2019
|
|
6JIF
| Crystal Structures of Branched-Chain Aminotransferase from Pseudomonas sp. UW4 | 分子名称: | Branched-chain-amino-acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Zheng, X, Guo, L, Li, D.F, Wu, B. | 登録日 | 2019-02-21 | 公開日 | 2020-01-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Biochemical and structural characterization of a highly active branched-chain amino acid aminotransferase from Pseudomonas sp. for efficient biosynthesis of chiral amino acids. Appl.Microbiol.Biotechnol., 103, 2019
|
|
6KY5
| Crystal structure of a hydrolase mutant | 分子名称: | PET hydrolase, SULFATE ION | 著者 | Cui, Y.L, Chen, Y.C, Liu, X.Y, Dong, S.J, Han, J, Xiang, H, Chen, Q, Liu, H.Y, Han, X, Liu, W.D, Tang, S.Y, Wu, B. | 登録日 | 2019-09-16 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.631 Å) | 主引用文献 | Computational redesign of PETase for plasticbiodegradation by GRAPE strategy. Biorxiv, 2020
|
|
6LML
| Cryo-EM structure of the human glucagon receptor in complex with Gi1 | 分子名称: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B. | 登録日 | 2019-12-26 | 公開日 | 2020-04-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
|
|
6LW5
| Crystal structure of the human formyl peptide receptor 2 in complex with WKYMVm | 分子名称: | CHOLESTEROL, Soluble cytochrome b562,N-formyl peptide receptor 2, TRP-LYS-TYR-MET-VAL-QXV | 著者 | Chen, T, Zong, X, Zhang, H, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2020-02-07 | 公開日 | 2020-03-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of ligand binding modes at the human formyl peptide receptor 2. Nat Commun, 11, 2020
|
|
6LMK
| Cryo-EM structure of the human glucagon receptor in complex with Gs | 分子名称: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qiao, A, Han, S, Tai, L, Sun, F, Zhao, Q, Wu, B. | 登録日 | 2019-12-26 | 公開日 | 2020-04-01 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
|
|
4MBS
| Crystal Structure of the CCR5 Chemokine Receptor | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl}-1-phenylpropyl]cyclohexanecarboxamide, Chimera protein of C-C chemokine receptor type 5 and Rubredoxin, ... | 著者 | Tan, Q, Zhu, Y, Han, G.W, Li, J, Fenalti, G, Liu, H, Cherezov, V, Stevens, R.C, GPCR Network (GPCR), Zhao, Q, Wu, B. | 登録日 | 2013-08-19 | 公開日 | 2013-09-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science, 341, 2013
|
|
4NQK
| Structure of an Ubiquitin complex | 分子名称: | Probable ATP-dependent RNA helicase DDX58, Ubiquitin | 著者 | Peisley, A, Wu, B, Hur, S. | 登録日 | 2013-11-25 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I. Nature, 509, 2014
|
|