2HG2
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2ILU
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1B2M
| THREE-DIMENSIONAL STRUCTURE OF RIBONULCEASE T1 COMPLEXED WITH AN ISOSTERIC PHOSPHONATE ANALOGUE OF GPU: ALTERNATE SUBSTRATE BINDING MODES AND CATALYSIS. | 分子名称: | 5'-R(*GP*(U34))-3', RIBONUCLEASE T1 | 著者 | Arni, R.K, Watanabe, L, Ward, R.J, Kreitman, R.J, Kumar, K, Walz Jr, F.G. | 登録日 | 1998-11-27 | 公開日 | 1999-03-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis. Biochemistry, 38, 1999
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3MJL
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3NB3
| The host outer membrane proteins OmpA and OmpC are packed at specific sites in the Shigella phage Sf6 virion as structural components | 分子名称: | Outer membrane protein A, Outer membrane protein C | 著者 | Zhao, H, Sequeira, R.D, Galeva, N.A, Tang, L. | 登録日 | 2010-06-02 | 公開日 | 2011-02-16 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (19 Å) | 主引用文献 | The host outer membrane proteins OmpA and OmpC are associated with the Shigella phage Sf6 virion. Virology, 409, 2011
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2JNR
| Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide | 分子名称: | ENV polyprotein, VIR165 | 著者 | Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. | 登録日 | 2007-02-01 | 公開日 | 2007-05-08 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
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4IDH
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4IEI
| Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6 complexed with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Gene 2 protein | 著者 | Zhao, H, Christensen, T, Kamau, Y, Tang, L. | 登録日 | 2012-12-13 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IOX
| The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | 著者 | Selvarajan Sigamani, S, Zhao, H, Kamau, Y, Tang, L. | 登録日 | 2013-01-08 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.458 Å) | 主引用文献 | The Structure of the Herpes Simplex Virus DNA-Packaging Terminase pUL15 Nuclease Domain Suggests an Evolutionary Lineage among Eukaryotic and Prokaryotic Viruses. J.Virol., 87, 2013
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4IEE
| Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6 complexed with ATP-r-S | 分子名称: | Gene 2 protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Zhao, H, Christensen, T, Kamau, Y, Tang, L. | 登録日 | 2012-12-13 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IFE
| Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6 complexed with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Gene 2 protein | 著者 | Zhao, H, Christensen, T, Kamau, Y, Tang, L. | 登録日 | 2012-12-14 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage. Proc.Natl.Acad.Sci.USA, 110, 2013
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3SKK
| Crystal structure of human arginase I in complex with the inhibitor FABH, Resolution 1.70 A, twinned structure | 分子名称: | Arginase-1, MANGANESE (II) ION, [(5S)-5-amino-5-carboxy-6,6-difluorohexyl](trihydroxy)borate(1-) | 著者 | Thorn, K.J, Di Costanzo, L, Christianson, D.W. | 登録日 | 2011-06-22 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J.Med.Chem., 54, 2011
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3CEZ
| Crystal structure of methionine-R-sulfoxide reductase from Burkholderia pseudomallei | 分子名称: | ACETIC ACID, Methionine-R-sulfoxide reductase, ZINC ION | 著者 | Staker, B, Napuli, A, Nakazawa, S.H, Castaneda, L, Alkafeef, S, Vanvoorhis, W, Stewart, L, Myler, P, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2008-02-29 | 公開日 | 2008-03-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Methionine-R-sulfoxide reductase from Burkholderia pseudomallei. To be Published
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4L36
| Crystal structure of the cytochrome P450 enzyme TxtE | 分子名称: | HEME B/C, IMIDAZOLE, Putative P450-like protein | 著者 | Yu, F, Li, M.J, Xu, C.Y, Wang, Z.J, Zhou, H, Yang, M, Chen, Y.X, Tang, L, He, J.H. | 登録日 | 2013-06-05 | 公開日 | 2013-12-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Structural Insights into the Mechanism for Recognizing Substrate of the Cytochrome P450 Enzyme TxtE. Plos One, 8, 2013
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5C10
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5C2D
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5C15
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5C12
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5C2F
| K428A mutant nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6 with Manganese and beta-thujaplicinol | 分子名称: | 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one, Gene 2 protein, MANGANESE (II) ION | 著者 | Zhao, H, Tang, L. | 登録日 | 2015-06-15 | 公開日 | 2015-10-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism. Nucleic Acids Res., 43, 2015
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3ZN2
| protein engineering of halohydrin dehalogenase | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETATE ION, HALOHYDRIN DEHALOGENASE, ... | 著者 | Schallmey, M, Jekel, P, Tang, L, Majeric-Elenkov, M, Hoeffken, H.W, Hauer, B, Janssen, D.B. | 登録日 | 2013-02-13 | 公開日 | 2014-03-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Single Point Mutation Enhances Hydroxynitrile Synthesis by Halohydrin Dehalogenase. Enzyme.Microb.Technol., 70, 2015
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2E4O
| X-ray Crystal Structure of Aristolochene Synthase from Aspergillus terreus and the Evolution of Templates for the Cyclization of Farnesyl Diphosphate | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aristolochene synthase, BETA-MERCAPTOETHANOL, ... | 著者 | Shishova, E.Y, Di Costanzo, L, Cane, D.E, Christianson, D.W. | 登録日 | 2006-12-15 | 公開日 | 2007-01-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate. Biochemistry, 46, 2007
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2F7K
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2OA6
| Aristolochene synthase from Aspergillus terreus complexed with pyrophosphate | 分子名称: | Aristolochene synthase, BETA-MERCAPTOETHANOL, GLYCEROL, ... | 著者 | Shishova, E.Y, Di Costanzo, L, Cane, D.E, Christianson, D.W. | 登録日 | 2006-12-15 | 公開日 | 2007-01-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate Biochemistry, 46, 2007
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2PLL
| Crystal structure of perdeuterated human arginase I | 分子名称: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, arginase-1 | 著者 | Di Costanzo, L, Moulin, M, Haertlein, M, Meilleur, F, Christianson, D.W. | 登録日 | 2007-04-19 | 公開日 | 2007-08-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Expression, purification, assay, and crystal structure of perdeuterated human arginase I Arch.Biochem.Biophys., 465, 2007
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2PHO
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