4IOX
The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors
Summary for 4IOX
| Entry DOI | 10.2210/pdb4iox/pdb |
| Descriptor | Tripartite terminase subunit UL15, peptide, TRIETHYLENE GLYCOL, ... (7 entities in total) |
| Functional Keywords | nuclease, viral protein |
| Biological source | Human herpesvirus 1 (HHV-1) More |
| Cellular location | Host nucleus: P04295 |
| Total number of polymer chains | 4 |
| Total formula weight | 93794.92 |
| Authors | Selvarajan Sigamani, S.,Zhao, H.,Kamau, Y.,Tang, L. (deposition date: 2013-01-08, release date: 2013-05-01, Last modification date: 2023-09-20) |
| Primary citation | Selvarajan Sigamani, S.,Zhao, H.,Kamau, Y.N.,Baines, J.D.,Tang, L. The Structure of the Herpes Simplex Virus DNA-Packaging Terminase pUL15 Nuclease Domain Suggests an Evolutionary Lineage among Eukaryotic and Prokaryotic Viruses. J.Virol., 87:7140-7148, 2013 Cited by PubMed: 23596306DOI: 10.1128/JVI.00311-13 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.458 Å) |
Structure validation
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