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6EUZ
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BU of 6euz by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK37)
分子名称: (3~{R})-8-methoxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, ...
著者Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2017-10-31
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
6EXL
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BU of 6exl by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - folded HTH motif
分子名称: ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, SODIUM ION, ...
著者Hall, M, Grundstrom, C, Begum, A, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2017-11-08
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
6EUU
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BU of 6euu by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (KSK29)
分子名称: (3~{R})-8-cyclopropyl-5-oxidanylidene-7-(quinolin-3-ylmethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, ...
著者Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2017-10-31
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
6EV0
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BU of 6ev0 by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (AC129)
分子名称: ISOPROPYL ALCOHOL, Listeriolysin regulatory protein, [(3~{R})-3-carboxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium, ...
著者Begum, A, Hall, M, Grundstrom, C, Cairns, A.G, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2017-10-31
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
6EXK
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BU of 6exk by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - unfolded HTH motif
分子名称: ISOPROPYL ALCOHOL, Listeriolysin regulatory protein, SODIUM ION, ...
著者Hall, M, Grundstrom, C, Begum, A, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2017-11-08
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
5J94
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BU of 5j94 by Molmil
Human cathepsin K mutant C25S in complex with the allosteric effector NSC13345
分子名称: 2-{[(carbamoylsulfanyl)acetyl]amino}benzoic acid, Cathepsin K, SULFATE ION
著者Novinec, M, Korenc, M, Lenarcic, B, Baici, A.
登録日2016-04-08
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.22002459 Å)
主引用文献A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods.
Nat Commun, 5, 2014
6ZWT
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BU of 6zwt by Molmil
Crystal structure of DNA-binding domain of OmpR of two-component system of Acinetobacter baumannii
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ...
著者Narwal, M, Lucchini, V, Trebosc, V, Gartenmann, S, Pieren, M, Kemmer, C, Kammerer, R.A.
登録日2020-07-28
公開日2021-08-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis.
Virulence, 13, 2022
8OOD
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BU of 8ood by Molmil
Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 15
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DDB1- and CUL4-associated factor 1, ...
著者Schroeder, M, Renatus, M.
登録日2023-04-05
公開日2023-05-24
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.497 Å)
主引用文献Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings
Biorxiv, 2023
8OO5
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BU of 8oo5 by Molmil
Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 13
分子名称: 1,2-ETHANEDIOL, 1-[4-[4-(2-azanylethylamino)-2-[1-(4-chlorophenyl)cyclohexyl]quinazolin-7-yl]piperazin-1-yl]ethanone, DDB1- and CUL4-associated factor 1
著者Schroeder, M, Renatus, M.
登録日2023-04-04
公開日2023-05-24
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings
Biorxiv, 2023
5MDU
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BU of 5mdu by Molmil
Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe.
分子名称: CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ...
著者Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J.
登録日2016-11-13
公開日2017-04-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
8PDP
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BU of 8pdp by Molmil
10-mer ring of HMPV N-RNA bound to the C-terminal region of P
分子名称: Nucleoprotein, Phosphoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDQ
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BU of 8pdq by Molmil
11-mer ring of HMPV N-RNA bound to the C-terminal region of P
分子名称: Nucleoprotein, Phosphoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDM
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BU of 8pdm by Molmil
11-mer ring of human metapneumovirus (HMPV) N-RNA
分子名称: Nucleoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDR
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BU of 8pdr by Molmil
Rigid body fit of assembled HMPV N-RNA spiral bound to the C-terminal region of P
分子名称: Nucleoprotein, Phosphoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDN
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BU of 8pdn by Molmil
Spiral of assembled human metapneumovirus (HMPV) N-RNA
分子名称: Nucleoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDO
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BU of 8pdo by Molmil
Local refinement of dimeric human metapneumovirus (HMPV) N-RNA
分子名称: Nucleoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDL
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BU of 8pdl by Molmil
10-mer ring of human metapneumovirus (HMPV) N-RNA
分子名称: Nucleoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDS
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BU of 8pds by Molmil
Local refinement of dimeric HMPV N-RNA bound to the C-terminal region of P
分子名称: Nucleoprotein, Phosphoprotein, RNA
著者Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
登録日2023-06-12
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
5MDT
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BU of 5mdt by Molmil
Structure of the CTD-interacting domain (CID) of Seb1 from S. pombe.
分子名称: Rpb7-binding protein seb1
著者Wittmann, S, Renner, M, Vasiljeva, L, Grimes, J.
登録日2016-11-13
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
4V69
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BU of 4v69 by Molmil
Ternary complex-bound E.coli 70S ribosome.
分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J.
登録日2008-12-11
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
Proc.Natl.Acad.Sci.USA, 106, 2009
5FOH
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BU of 5foh by Molmil
Crystal structure of the catalytic domain of NcLPMO9A
分子名称: COPPER (II) ION, LITHIUM ION, POLYSACCHARIDE MONOOXYGENASE, ...
著者Westereng, B, Kracun, S.K, Dimarogona, M, Mathiesen, G, Willats, W.G.T, Sandgren, M, Aachmann, F.L, Eijsink, V.G.H.
登録日2015-11-18
公開日2016-12-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Comparison of three seemingly similar lytic polysaccharide monooxygenases fromNeurospora crassasuggests different roles in plant biomass degradation.
J.Biol.Chem., 2019
8B3Q
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BU of 8b3q by Molmil
CryoEM structure of the central filamentous region of the f1 filamentous bacteriophage, consisting of the major capsid protein pVIII
分子名称: Capsid protein G8P
著者Conners, R, McLaren, M, Gold, V.A.M.
登録日2022-09-16
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly.
Nat Commun, 14, 2023
8B3P
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BU of 8b3p by Molmil
CryoEM structure of the round tip (proteins pVII/pVIII/pIX) from the f1 filamentous bacteriophage
分子名称: Capsid protein G8P, Tail virion protein G7P, Tail virion protein G9P
著者Conners, R, McLaren, M, Gold, V.A.M.
登録日2022-09-16
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly.
Nat Commun, 14, 2023
8B3O
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BU of 8b3o by Molmil
CryoEM structure of the pointy tip (proteins pIII/pVI/pVIII) from the f1 filamentous bacteriophage
分子名称: Attachment protein G3P, Capsid protein G8P, Head virion protein G6P
著者Conners, R, McLaren, M, Gold, V.A.M.
登録日2022-09-16
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly.
Nat Commun, 14, 2023
5AE6
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BU of 5ae6 by Molmil
The structure of Hypocrea jecorina beta-xylosidase Xyl3A (Bxl1) in complex with 4-thioxylobiose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-XYLOSIDASE, ...
著者Mikkelsen, N.E, Gudmundsson, M, Karkehabadi, S, Hansson, H, Sandgren, M, Larenas, E, Mitchinson, C, Keleman, B, Kaper, T.
登録日2015-08-26
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Th Crystal Structure of a Fungal Glycoside Hydrolase Family 3 Beta-Xylosidase, Xyl3A from Hypocrea Jecorina
To be Published

222926

件を2024-07-24に公開中

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