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5XS2
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CDK8-CYCC IN COMPLEX WITH COMPOUND 17:3-chloro-4-(4-pyridyl)-1H-pyrrole-2-carboxamide
分子名称: 3-chloranyl-4-pyridin-4-yl-1H-pyrrole-2-carboxamide, Cyclin-C, Cyclin-dependent kinase 8, ...
著者Zhou, Z, Xu, Z.
登録日2017-06-12
公開日2017-08-09
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Discovery of potent and selective CDK8 inhibitors through FBDD approach
Bioorg. Med. Chem. Lett., 27, 2017
7XO4
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BU of 7xo4 by Molmil
SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with two mouse ACE2 Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-04-30
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XOA
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SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with one mouse ACE2 Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XO5
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BU of 7xo5 by Molmil
SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with one mouse ACE2 Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XO9
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BU of 7xo9 by Molmil
SARS-CoV-2 Omicron BA.2 Variant RBD complexed with human ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XO7
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BU of 7xo7 by Molmil
SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two human ACE2 Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XO8
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BU of 7xo8 by Molmil
SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three human ACE2 Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XO6
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BU of 7xo6 by Molmil
SARS-CoV-2 Omicron BA.1 Variant RBD with mouse ACE2 Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XOC
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BU of 7xoc by Molmil
SARS-CoV-2 Omicron BA.2 Variant RBD complexed with mouse ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XOD
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BU of 7xod by Molmil
SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three JMB2002 Fab Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of JMB2002 Fab, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7XOB
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BU of 7xob by Molmil
SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two mouse ACE2 Bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
著者Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E.
登録日2022-05-01
公開日2022-06-15
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
7WVM
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BU of 7wvm by Molmil
The complex structure of PD-1 and cemiplimab
分子名称: Heavy Chain of Cemiplimab, Light Chain of Cemiplimab, Programmed cell death protein 1
著者Lu, D, Xu, Z.P, Liu, K.F, Tan, S.G, Gao, G.F, Chai, Y.
登録日2022-02-10
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy.
Front Immunol, 13, 2022
2KW6
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BU of 2kw6 by Molmil
Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H
分子名称: Cyclin-dependent kinase 2-associated protein 1
著者Ertekin, A, Aramini, J.M, Rossi, P, Lee, A.B, Jiang, M, Ciccosanti, C.T, Xiao, R, Swapna, G.V.T, Rost, B, Everett, J.K, Acton, T.B, Prestegard, J.H, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2010-03-31
公開日2010-05-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region.
J.Biol.Chem., 287, 2012
2JN7
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BU of 2jn7 by Molmil
Northeast Structural Genomics Consortium Target ER411
分子名称: protein yfjZ
著者Tian, F, Zhao, L, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-28
公開日2007-01-09
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR solution structure of E.Coli hypothetical protein YFJZ
To be Published
2JVA
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BU of 2jva by Molmil
NMR solution structure of peptidyl-tRNA hydrolase domain protein from Pseudomonas syringae pv. tomato. Northeast Structural Genomics Consortium target PsR211
分子名称: Peptidyl-tRNA hydrolase domain protein
著者Singarapu, K.K, Sukumaran, D, Parish, D, Eletsky, A, Zhang, Q, Zhao, L, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Huang, Y.J, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2007-09-14
公開日2007-10-02
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR structure of the peptidyl-tRNA hydrolase domain from Pseudomonas syringae expands the structural coverage of the hydrolysis domains of class 1 peptide chain release factors.
Proteins, 71, 2008
2K50
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BU of 2k50 by Molmil
Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.
分子名称: Replication factor A related protein
著者Rossi, P, Xiao, R, Maglaqui, M, Foote, E.L, Ciccosanti, C, Swapna, G, Acton, T.B, Rost, B, Everett, J.K, Jiang, M, Nair, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-23
公開日2008-07-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.
To be Published
2KF2
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BU of 2kf2 by Molmil
Solution NMR structure of of Streptomyces coelicolor polyketide cyclase SCO5315. Northeast Structural Genomics Consortium target RR365
分子名称: Putative polyketide cyclase
著者Cort, J.R, Ramelot, T.A, Ding, K, Wang, H, Jiang, M, Maglaqui, M, Xiao, R, Nair, R, Baran, M.C, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2009-02-11
公開日2009-05-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Streptomyces coelicolor polyketide cyclase SCO5315
To be Published
2KD1
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BU of 2kd1 by Molmil
Solution NMR structure of the integrase-like domain from Bacillus cereus ordered locus BC_1272. Northeast Structural Genomics Consortium Target BcR268F
分子名称: DNA integration/recombination/invertion protein
著者Rossi, P, Lee, H, Maglaqui, M, Foote, E.L, Buchwald, W.A, Jiang, M, Swapna, G.V.T, Nair, R, Xiao, R, Acton, T.B, Rost, B, Prestegard, J.H, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-12-31
公開日2009-01-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the Integrase-Like Domain from Bacillus cereus Ordered Locus BC_1272. Northeast Structural Genomics Consortium Target BcR268F.
To be Published
2K5K
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BU of 2k5k by Molmil
Solution structure of RhR2 from Rhodobacter Sphaeroides. Northeast Structural Genomics Consortium
分子名称: uncharacterized protein RhR2
著者Lee, H, Bansal, S, Chen, C.X, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-28
公開日2008-08-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of RhR2
To be Published
2K57
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BU of 2k57 by Molmil
Solution NMR Structure of Putative Lipoprotein from Pseudomonas syringae Gene Locus PSPTO2350. Northeast Structural Genomics Target PsR76A.
分子名称: Putative Lipoprotein
著者Hang, D, Aramini, J.A, Rossi, P, Wang, D, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-25
公開日2008-09-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Putative Lipoprotein from Pseudomonas syringae Gene Locus PSPTO2350. Northeast Structural Genomics Target PsR76A.
To be Published
6JHO
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BU of 6jho by Molmil
The complex crystal structure of Cagbeta with CagZ revealed a novel regulatory mechanism for T4SS coupling ATPase in Helicobacter pylori
分子名称: Cag pathogenicity island protein (Cag5), Cag pathogenicity island protein (Cag6)
著者Wu, X, Zhao, Y, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Wu, Y.
登録日2019-02-18
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The complex crystal structure of Cagbeta with CagZ revealed a novel regulatory mechanism in VirD4 coupling ATPase
To Be Published
6DUK
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BU of 6duk by Molmil
EGFR with an allosteric inhibitor
分子名称: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, MAGNESIUM ION, ...
著者Park, E, Eck, M.J.
登録日2018-06-21
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor.
Cancer Discov, 9, 2019
2KL8
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BU of 2kl8 by Molmil
Solution NMR Structure of de novo designed ferredoxin-like fold protein, Northeast Structural Genomics Consortium Target OR15
分子名称: OR15
著者Liu, G, Koga, N, Jiang, M, Koga, R, Xiao, R, Ciccosanti, C, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2009-06-30
公開日2009-07-28
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Principles for designing ideal protein structures.
Nature, 491, 2012
2K5E
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BU of 2k5e by Molmil
SOLUTION STRUCTURE OF PUTATIVE UNCHARACTERIZED PROTEIN GSU1278 FROM METHANOCALDOCOCCUS JANNASCHII, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET GsR195
分子名称: uncharacterized protein
著者Liu, G, Zhao, L, Ciccosanti, C, Jiang, M, Xiao, R, Swapna, G, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-27
公開日2008-08-26
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献SOLUTION STRUCTURE OF PUTATIVE UNCHARACTERIZED PROTEIN GSU1278 FROM METHANOCALDOCOCCUS JANNASCHII, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET GsR195
To be Published
2K1H
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BU of 2k1h by Molmil
Solution NMR structure of SeR13 from Staphylococcus epidermidis. Northeast Structural Genomics Consortium target SeR13
分子名称: Uncharacterized protein SeR13
著者Lee, H, Wylie, G, Bansal, S, Wang, X, Shastry, R, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG)
登録日2008-03-05
公開日2008-03-18
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution Structure of SeR13.
To be Published

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件を2024-07-17に公開中

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