2KW6

Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H

Summary for 2KW6

• Entry DOI: 10.2210/pdb2kw6/pdb
• NMR Information: BMRB: 16808
• Descriptor: Cyclin-dependent kinase 2-associated protein 1 (1 entity in total)
• Functional Keywords: structural genomics, northeast structural genomics consortium (nesg), psi-2, protein structure initiative, cancer suppressor, cell cycle
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 14881.08

Authors

Ertekin, A.,Aramini, J.M.,Rossi, P.,Lee, A.B.,Jiang, M.,Ciccosanti, C.T.,Xiao, R.,Swapna, G.V.T.,Rost, B.,Everett, J.K.,Acton, T.B.,Prestegard, J.H.,Montelione, G.T.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2010-03-31, release date: 2010-05-26, Last modification date: 2024-05-15)

• Primary citation: Ertekin, A.,Aramini, J.M.,Rossi, P.,Leonard, P.G.,Janjua, H.,Xiao, R.,Maglaqui, M.,Lee, H.W.,Prestegard, J.H.,Montelione, G.T.; Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region.; J.Biol.Chem., 287:16541-16549, 2012; PubMed: 22427660; DOI: 10.1074/jbc.M112.343863

Experimental method

SOLUTION NMR