2KW6
Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H
Summary for 2KW6
Entry DOI | 10.2210/pdb2kw6/pdb |
NMR Information | BMRB: 16808 |
Descriptor | Cyclin-dependent kinase 2-associated protein 1 (1 entity in total) |
Functional Keywords | structural genomics, northeast structural genomics consortium (nesg), psi-2, protein structure initiative, cancer suppressor, cell cycle |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 14881.08 |
Authors | Ertekin, A.,Aramini, J.M.,Rossi, P.,Lee, A.B.,Jiang, M.,Ciccosanti, C.T.,Xiao, R.,Swapna, G.V.T.,Rost, B.,Everett, J.K.,Acton, T.B.,Prestegard, J.H.,Montelione, G.T.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2010-03-31, release date: 2010-05-26, Last modification date: 2024-05-15) |
Primary citation | Ertekin, A.,Aramini, J.M.,Rossi, P.,Leonard, P.G.,Janjua, H.,Xiao, R.,Maglaqui, M.,Lee, H.W.,Prestegard, J.H.,Montelione, G.T. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region. J.Biol.Chem., 287:16541-16549, 2012 Cited by PubMed: 22427660DOI: 10.1074/jbc.M112.343863 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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