7XO7

SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two human ACE2 Bound

Summary for 7XO7

• Entry DOI: 10.2210/pdb7xo7/pdb
• EMDB information: 33336 33337 33338 33339 33340 33341 33342 33343 33344 33345
• Descriptor: Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: viral protein-hydrolase complex, viral protein/hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 5
• Total formula weight: 617138.44

Authors

Xu, Y.,Wu, C.,Liu, H.,Yin, W.,Xu, H.E. (deposition date: 2022-05-01, release date: 2022-06-15, Last modification date: 2022-07-13)

• Primary citation: Xu, Y.,Wu, C.,Cao, X.,Gu, C.,Liu, H.,Jiang, M.,Wang, X.,Yuan, Q.,Wu, K.,Liu, J.,Wang, D.,He, X.,Wang, X.,Deng, S.J.,Xu, H.E.,Yin, W.; Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.; Cell Res., 32:609-620, 2022; PubMed: 35641567; DOI: 10.1038/s41422-022-00672-4

Experimental method

ELECTRON MICROSCOPY (3.38 Å)