4R4H
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![BU of 4r4h by Molmil](/molmil-images/mine/4r4h) | Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ... | 著者 | Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D. | 登録日 | 2014-08-19 | 公開日 | 2014-09-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.28 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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4ZS3
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![BU of 4zs3 by Molmil](/molmil-images/mine/4zs3) | Structural complex of 5-aminofluorescein bound to the FTO protein | 分子名称: | 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | 著者 | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | 登録日 | 2015-05-13 | 公開日 | 2015-11-04 | 最終更新日 | 2015-11-18 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
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4ZS2
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![BU of 4zs2 by Molmil](/molmil-images/mine/4zs2) | Structural complex of FTO/fluorescein | 分子名称: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | 著者 | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | 登録日 | 2015-05-13 | 公開日 | 2015-11-04 | 最終更新日 | 2015-11-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
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4R4N
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![BU of 4r4n by Molmil](/molmil-images/mine/4r4n) | Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ... | 著者 | Acharya, P, Louder, R, Kwong, P.D. | 登録日 | 2014-08-19 | 公開日 | 2014-11-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.56 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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4R4F
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![BU of 4r4f by Molmil](/molmil-images/mine/4r4f) | Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 YU2 gp120 | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, ... | 著者 | Acharya, P, Kwong, P.D. | 登録日 | 2014-08-19 | 公開日 | 2014-09-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.514 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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8GUG
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![BU of 8gug by Molmil](/molmil-images/mine/8gug) | Structure of VPA0770 toxin bound to VPA0769 antitoxin in Vibrio parahaemolyticus | 分子名称: | DUF2384 domain-containing protein, RES domain-containing protein | 著者 | Song, X.J, Zhang, Y, Xu, Y.Y, Lin, Z. | 登録日 | 2022-09-12 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural insights of the toxin-antitoxin system VPA0770-VPA0769 in Vibrio parahaemolyticus. Int.J.Biol.Macromol., 242, 2023
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8YJY
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![BU of 8yjy by Molmil](/molmil-images/mine/8yjy) | |
2QFW
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![BU of 2qfw by Molmil](/molmil-images/mine/2qfw) | |
2RKI
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![BU of 2rki by Molmil](/molmil-images/mine/2rki) | Crystal Structure of HIV-1 Reverse Transcriptase (RT) in Complex with a triazole derived NNRTI | 分子名称: | 4-benzyl-3-[(2-chlorobenzyl)sulfanyl]-5-thiophen-2-yl-4H-1,2,4-triazole, CHLORIDE ION, GLYCEROL, ... | 著者 | Lansdon, E.B, Kirschberg, T.A. | 登録日 | 2007-10-16 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase-structure-activity relationships and crystallographic analysis. Bioorg.Med.Chem.Lett., 18, 2008
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4H8W
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![BU of 4h8w by Molmil](/molmil-images/mine/4h8w) | Crystal structure of non-neutralizing and ADCC-potent antibody N5-i5 in complex with HIV-1 clade A/E gp120 and sCD4. | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ... | 著者 | Tolbert, W.D, Acharya, P, Kwong, P.D, Pazgier, M. | 登録日 | 2012-09-24 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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8EMR
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![BU of 8emr by Molmil](/molmil-images/mine/8emr) | Cryo-EM structure of human liver glucosidase II | 分子名称: | CALCIUM ION, Glucosidase 2 subunit beta, Neutral alpha-glucosidase AB, ... | 著者 | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | 登録日 | 2022-09-28 | 公開日 | 2023-05-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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8EMT
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![BU of 8emt by Molmil](/molmil-images/mine/8emt) | Cryo-EM analysis of the human aldehyde oxidase from liver | 分子名称: | Aldehyde oxidase, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | 登録日 | 2022-09-28 | 公開日 | 2023-05-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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8EMS
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![BU of 8ems by Molmil](/molmil-images/mine/8ems) | Cryo-EM structure of human liver glycogen phosphorylase | 分子名称: | Glycogen phosphorylase, liver form, PYRIDOXAL-5'-PHOSPHATE | 著者 | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | 登録日 | 2022-09-28 | 公開日 | 2023-05-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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7C01
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![BU of 7c01 by Molmil](/molmil-images/mine/7c01) | Molecular basis for a potent human neutralizing antibody targeting SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CB6 heavy chain, CB6 light chain, ... | 著者 | Shi, R, Qi, J, Wang, Q, Gao, F.G, Yan, J. | 登録日 | 2020-04-29 | 公開日 | 2020-05-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2. Nature, 584, 2020
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3STO
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![BU of 3sto by Molmil](/molmil-images/mine/3sto) | Serpin from the trematode Schistosoma Haematobium | 分子名称: | Serine protease inhibitor | 著者 | Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E. | 登録日 | 2011-07-11 | 公開日 | 2012-05-30 | 最終更新日 | 2013-01-23 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain. Acta Crystallogr.,Sect.D, 68, 2012
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8H6T
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8H6P
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![BU of 8h6p by Molmil](/molmil-images/mine/8h6p) | Complex structure of CDK2/Cyclin E1 and a potent, selective macrocyclic inhibitor | 分子名称: | (7S,10R)-11-oxa-2,4,5,13,17,23-hexaazatetracyclo[17.3.1.1~3,6~.1~7,10~]pentacosa-1(23),3(25),5,19,21-pentaene-12,18-dione, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | 著者 | Ren, X. | 登録日 | 2022-10-18 | 公開日 | 2023-02-22 | 最終更新日 | 2023-03-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design. Acs Med.Chem.Lett., 14, 2023
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1PZV
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![BU of 1pzv by Molmil](/molmil-images/mine/1pzv) | Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans | 分子名称: | Probable ubiquitin-conjugating enzyme E2-19 kDa | 著者 | Schormann, N, Lin, G, Li, S, Symersky, J, Qiu, S, Finley, J, Luo, D, Stanton, A, Carson, M, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2003-07-14 | 公開日 | 2003-07-22 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans To be Published
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1BS1
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![BU of 1bs1 by Molmil](/molmil-images/mine/1bs1) | DETHIOBIOTIN SYNTHETASE COMPLEXED WITH DETHIOBIOTIN, ADP , INORGANIC PHOSPHATE AND MAGNESIUM | 分子名称: | 8-AMINO-7-CARBOXYAMINO-NONANOIC ACID WITH ALUMINUM FLUORIDE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kaeck, H, Sandmark, J, Gibson, K.J, Schneider, G, Lindqvist, Y. | 登録日 | 1998-08-31 | 公開日 | 1999-01-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis. Protein Sci., 7, 1998
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1A0Q
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![BU of 1a0q by Molmil](/molmil-images/mine/1a0q) | 29G11 COMPLEXED WITH PHENYL [1-(1-N-SUCCINYLAMINO)PENTYL] PHOSPHONATE | 分子名称: | 29G11 FAB (HEAVY CHAIN), 29G11 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE, ... | 著者 | Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J. | 登録日 | 1997-12-05 | 公開日 | 1999-03-02 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A comparison of the crystallographic structures of two catalytic antibodies with esterase activity. J.Mol.Biol., 282, 1998
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1BYI
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![BU of 1byi by Molmil](/molmil-images/mine/1byi) | STRUCTURE OF APO-DETHIOBIOTIN SYNTHASE AT 0.97 ANGSTROMS RESOLUTION | 分子名称: | DETHIOBIOTIN SYNTHASE | 著者 | Sandalova, T, Schneider, G, Kaeck, H, Lindqvist, Y. | 登録日 | 1998-10-15 | 公開日 | 1999-06-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Structure of dethiobiotin synthetase at 0.97 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
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8XN7
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![BU of 8xn7 by Molmil](/molmil-images/mine/8xn7) | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f | 分子名称: | 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1 | 著者 | Huang, W.X, Liu, R, Ding, K. | 登録日 | 2023-12-29 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors. Eur.J.Med.Chem., 269, 2024
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4NOJ
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![BU of 4noj by Molmil](/molmil-images/mine/4noj) | Crystal structure of the mature form of asparaginyl endopeptidase (AEP)/Legumain activated at pH 3.5 | 分子名称: | Legumain | 著者 | Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J. | 登録日 | 2013-11-19 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage. Cell Res., 24, 2014
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4NOL
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![BU of 4nol by Molmil](/molmil-images/mine/4nol) | Crystal structure of proenzyme asparaginyl endopeptidase (AEP)/Legumain mutant D233A at pH 7.5 | 分子名称: | Legumain | 著者 | Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J. | 登録日 | 2013-11-19 | 公開日 | 2014-02-19 | 最終更新日 | 2014-03-19 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage. Cell Res., 24, 2014
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4NOM
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![BU of 4nom by Molmil](/molmil-images/mine/4nom) | Crystal structure of asparaginyl endopeptidase (AEP)/Legumain activated at pH 4.5 | 分子名称: | Legumain | 著者 | Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J. | 登録日 | 2013-11-19 | 公開日 | 2014-02-19 | 最終更新日 | 2014-03-19 | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | 主引用文献 | Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage. Cell Res., 24, 2014
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