7BZO
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![BU of 7bzo by Molmil](/molmil-images/mine/7bzo) | Cryo-EM structure of mature Coxsackievirus A10 at pH 5.5 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | 登録日 | 2020-04-28 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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7BZU
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![BU of 7bzu by Molmil](/molmil-images/mine/7bzu) | Cryo-EM structure of mature Coxsackievirus A10 in complex with KRM1 at pH 5.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP2, ... | 著者 | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | 登録日 | 2020-04-28 | 公開日 | 2020-07-22 | 最終更新日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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5GZN
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![BU of 5gzn by Molmil](/molmil-images/mine/5gzn) | Structure of neutralizing antibody bound to Zika envelope protein | 分子名称: | Antibody Heavy chain, Antibody light chain, Genome polyprotein | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2016-09-29 | 公開日 | 2016-12-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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5ISL
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8KI4
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![BU of 8ki4 by Molmil](/molmil-images/mine/8ki4) | Crystal structure of human HSP90 in intermediate state | 分子名称: | 1,2-ETHANEDIOL, Heat shock protein HSP 90-alpha | 著者 | Xu, C, Zhang, X.L, Bai, F. | 登録日 | 2023-08-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies. Jacs Au, 4, 2024
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7BZT
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![BU of 7bzt by Molmil](/molmil-images/mine/7bzt) | Cryo-EM structure of mature Coxsackievirus A10 in complex with KRM1 at pH 7.4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP2, ... | 著者 | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | 登録日 | 2020-04-28 | 公開日 | 2020-07-22 | 最終更新日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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2K8H
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5IVE
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![BU of 5ive by Molmil](/molmil-images/mine/5ive) | Linked KDM5A Jmj Domain Bound to the Inhibitor N8 ( 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile) | 分子名称: | 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, MANGANESE (II) ION | 著者 | Horton, J.R, Cheng, X. | 登録日 | 2016-03-20 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.783 Å) | 主引用文献 | Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chem Biol, 23, 2016
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5GZO
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![BU of 5gzo by Molmil](/molmil-images/mine/5gzo) | Structure of neutralizing antibody bound to Zika envelope protein | 分子名称: | Antibody heavy chain, Antibody light chain, Genome polyprotein | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2016-09-29 | 公開日 | 2017-01-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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5DZN
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2LI6
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![BU of 2li6 by Molmil](/molmil-images/mine/2li6) | |
3UI7
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![BU of 3ui7 by Molmil](/molmil-images/mine/3ui7) | Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia | 分子名称: | 6-methoxy-3,8-dimethyl-4-(morpholin-4-ylmethyl)-1H-pyrazolo[3,4-b]quinoline, MAGNESIUM ION, ZINC ION, ... | 著者 | Yang, S, Smotryski, J, Mcelroy, W, Ho, G, Tulshian, D, Greenlee, W.J, Hodgson, R, Xiao, L, Hruza, A. | 登録日 | 2011-11-04 | 公開日 | 2011-12-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Bioorg.Med.Chem.Lett., 22, 2012
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4OAS
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![BU of 4oas by Molmil](/molmil-images/mine/4oas) | co-crystal structure of MDM2 (17-111) in complex with compound 25 | 分子名称: | E3 ubiquitin-protein ligase Mdm2, SULFATE ION, [(3R,5R,6S)-1-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetic acid | 著者 | Huang, X. | 登録日 | 2014-01-06 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2-p53 Inhibitor in Clinical Development. J.Med.Chem., 57, 2014
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7C4Z
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![BU of 7c4z by Molmil](/molmil-images/mine/7c4z) | Cryo-EM structure of empty Coxsackievirus A10 at pH 5.5 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | 著者 | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | 登録日 | 2020-05-18 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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7C4Y
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![BU of 7c4y by Molmil](/molmil-images/mine/7c4y) | Cryo-EM structure of empty Coxsackievirus A10 at pH 7.4 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | 著者 | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | 登録日 | 2020-05-18 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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5DZO
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7C4T
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![BU of 7c4t by Molmil](/molmil-images/mine/7c4t) | Cryo-EM structure of A particle Coxsackievirus A10 at pH 7.4 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | 著者 | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | 登録日 | 2020-05-18 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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7C4W
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![BU of 7c4w by Molmil](/molmil-images/mine/7c4w) | Cryo-EM structure of A particle Coxsackievirus A10 at pH 5.5 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | 著者 | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | 登録日 | 2020-05-18 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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2MQG
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7YPZ
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![BU of 7ypz by Molmil](/molmil-images/mine/7ypz) | Zafirlukast in complex with CRM1-Ran-RanBP1 | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | 著者 | Sun, Q, Lei, Y. | 登録日 | 2022-08-05 | 公開日 | 2023-08-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach. J.Med.Chem., 66, 2023
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2N7S
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2NB4
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![BU of 2nb4 by Molmil](/molmil-images/mine/2nb4) | Solution structure of Q388A3 PDZ domain | 分子名称: | Putative uncharacterized protein | 著者 | Mei, S. | 登録日 | 2016-01-24 | 公開日 | 2016-02-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Q388A3 PDZ domain from Trypanosoma brucei J.Struct.Biol., 194, 2016
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5GZR
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![BU of 5gzr by Molmil](/molmil-images/mine/5gzr) | Zika virus E protein complexed with a neutralizing antibody Z23-Fab | 分子名称: | Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ... | 著者 | Gao, G.G, Shi, Y, Peng, R, Liu, S. | 登録日 | 2016-10-01 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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7BR8
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![BU of 7br8 by Molmil](/molmil-images/mine/7br8) | Epstein-Barr virus, C5 penton vertex, CATC absent. | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | 著者 | Li, Z, Yu, X. | 登録日 | 2020-03-26 | 公開日 | 2020-09-30 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | CryoEM structure of the tegumented capsid of Epstein-Barr virus. Cell Res., 30, 2020
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7BSI
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