8ECG
| Complex of HMG1 with pitavastatin | 分子名称: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, GLYCEROL, Pitavastatin | 著者 | Haywood, J, Bond, C.S. | 登録日 | 2022-09-01 | 公開日 | 2022-09-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | A fungal tolerance trait and selective inhibitors proffer HMG-CoA reductase as a herbicide mode-of-action. Nat Commun, 13, 2022
|
|
5B7N
| |
5B7P
| |
5B7G
| |
1R9H
| |
5B7Q
| |
7V41
| Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with toluene. | 分子名称: | PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, TOLUENE, ... | 著者 | Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-08-12 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
|
|
7V44
| Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with meta-chlorotoluene. | 分子名称: | 1-chloranyl-2-methyl-benzene, GLYCEROL, PHOSPHATE ION, ... | 著者 | Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-08-12 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
|
|
7V43
| Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with para-chlorotoluene. | 分子名称: | 1-chloranyl-4-methyl-benzene, GLYCEROL, PHOSPHATE ION, ... | 著者 | Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-08-12 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
|
|
7V45
| Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with para-bromotoluene. | 分子名称: | 1-bromanyl-4-methyl-benzene, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-08-12 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
|
|
7V46
| Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with ortho-chlorotoluene. | 分子名称: | 1-chloranyl-3-methyl-benzene, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-08-12 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
|
|
8SBG
| |
8SIJ
| |
8SL7
| |
5K8K
| Structure of the Haemophilus influenzae LpxH-lipid X complex | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, ACETATE ION, GLYCEROL, ... | 著者 | Cho, J, Lee, C.-J, Zhou, P. | 登録日 | 2016-05-30 | 公開日 | 2016-08-10 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis. Nat Microbiol, 1, 2016
|
|
8T5K
| Crystal structure of STING CTD in complex with BDW-OH | 分子名称: | Stimulator of interferon genes protein, {[(4S)-8,9-dimethylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3-yl]sulfanyl}acetic acid | 著者 | Li, Y, Li, P, Sun, D. | 登録日 | 2023-06-13 | 公開日 | 2023-07-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023
|
|
8T5L
| |
7BW4
| Structure of the RNA-dependent RNA polymerase from SARS-CoV-2 | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Peng, Q, Peng, R, Shi, Y. | 登録日 | 2020-04-13 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2. Cell Rep, 31, 2020
|
|
8X5E
| Cryo-EM structure of human XPR1 in open state | 分子名称: | PHOSPHATE ION, Solute carrier family 53 member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Jiang, D.H, Yan, R. | 登録日 | 2023-11-17 | 公開日 | 2024-07-03 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Human XPR1 structures reveal phosphate export mechanism. Nature, 633, 2024
|
|
8X5B
| Cryo-EM structures of human XPR1 in closed states | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, PHOSPHATE ION, ... | 著者 | Jiang, D.H, Yan, R. | 登録日 | 2023-11-16 | 公開日 | 2024-07-03 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Human XPR1 structures reveal phosphate export mechanism. Nature, 633, 2024
|
|
8X5F
| human XPR1 in complex with InsP6 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Jiang, D.H, Yan, R. | 登録日 | 2023-11-17 | 公開日 | 2024-07-03 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Human XPR1 structures reveal phosphate export mechanism. Nature, 633, 2024
|
|
6K7P
| Crystal structure of human AFF4-THD domain | 分子名称: | AF4/FMR2 family member 4 | 著者 | Tang, D, Xue, Y, Li, S, Cheng, W, Duan, J, Wang, J, Qi, S. | 登録日 | 2019-06-08 | 公開日 | 2020-03-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription. Cell Discov, 6, 2020
|
|
5H3R
| Crystal Structure of mutant MarR C80S from E.coli complexed with operator DNA | 分子名称: | DNA (5'-D(*CP*AP*TP*AP*CP*TP*TP*GP*CP*CP*TP*GP*GP*GP*CP*AP*AP*TP*AP*TP*T)-3'), DNA (5'-D(*GP*AP*AP*TP*AP*TP*TP*GP*CP*CP*CP*AP*GP*GP*CP*AP*AP*GP*TP*AP*T)-3'), Multiple antibiotic resistance protein MarR | 著者 | Zhu, R, Lou, H, Hao, Z. | 登録日 | 2016-10-26 | 公開日 | 2017-08-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Structural characterization of the DNA-binding mechanism underlying the copper(II)-sensing MarR transcriptional regulator. J. Biol. Inorg. Chem., 22, 2017
|
|
5ED6
| crystal structure of human Hint1 H114A mutant complexing with ATP | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 | 著者 | Wang, J, Fang, P, Guo, M. | 登録日 | 2015-10-20 | 公開日 | 2017-01-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10, 2019
|
|
3C0C
| |