6DMO
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8PHI
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![BU of 8phi by Molmil](/molmil-images/mine/8phi) | Crystal structure of prefusion-stabilized RSV F Variant DS-Cav1 in complex with Lonafarnib | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, CALCIUM ION, ... | 著者 | Rajak, M, Krey, T. | 登録日 | 2023-06-19 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | 主引用文献 | Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nat Commun, 15, 2024
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222L
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![BU of 222l by Molmil](/molmil-images/mine/222l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-06-25 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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227L
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![BU of 227l by Molmil](/molmil-images/mine/227l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-06-25 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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229L
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![BU of 229l by Molmil](/molmil-images/mine/229l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GUANIDINE, ... | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-06-26 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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8PVQ
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![BU of 8pvq by Molmil](/molmil-images/mine/8pvq) | Crystal Structure of Human PTX3 C-terminal domain | 分子名称: | Pentraxin-related protein PTX3 | 著者 | Levy, C.W. | 登録日 | 2023-07-18 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Pentraxin 3 mediated crosslinking of heavy chain hyaluronan complexes: new insights from structural and biophysical studies To Be Published
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252L
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![BU of 252l by Molmil](/molmil-images/mine/252l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-10-28 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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6L1T
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![BU of 6l1t by Molmil](/molmil-images/mine/6l1t) | Cryo-EM structure of phosphorylated Tyr39 a-synuclein amyloid fibril | 分子名称: | Alpha-synuclein | 著者 | Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y. | 登録日 | 2019-09-30 | 公開日 | 2020-08-12 | 最終更新日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
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7EKE
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![BU of 7eke by Molmil](/molmil-images/mine/7eke) | Structure of SARS-CoV-2 spike receptor-binding domain F486L mutation complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKC
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![BU of 7ekc by Molmil](/molmil-images/mine/7ekc) | Structure of SARS-CoV-2 Gamma variant spike receptor-binding domain complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKG
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![BU of 7ekg by Molmil](/molmil-images/mine/7ekg) | Structure of SARS-CoV-2 Beta variant spike receptor-binding domain complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKH
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![BU of 7ekh by Molmil](/molmil-images/mine/7ekh) | Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKF
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![BU of 7ekf by Molmil](/molmil-images/mine/7ekf) | Structure of SARS-CoV-2 Alpha variant spike receptor-binding domain complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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6L1U
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![BU of 6l1u by Molmil](/molmil-images/mine/6l1u) | Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril | 分子名称: | Alpha-synuclein | 著者 | Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y. | 登録日 | 2019-09-30 | 公開日 | 2020-08-12 | 最終更新日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
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220L
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![BU of 220l by Molmil](/molmil-images/mine/220l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-06-25 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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225L
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![BU of 225l by Molmil](/molmil-images/mine/225l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | BETA-MERCAPTOETHANOL, PARA-XYLENE, T4 LYSOZYME | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-06-25 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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8SEI
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![BU of 8sei by Molmil](/molmil-images/mine/8sei) | SF Tau from Down Syndrome | 分子名称: | Microtubule-associated protein tau | 著者 | Hoq, M.R, Bharath, S.R, Jiang, W, Vago, F.S, Bharath, S.R. | 登録日 | 2023-04-10 | 公開日 | 2024-04-03 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 31, 2024
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8SEH
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8SEK
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8SEL
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![BU of 8sel by Molmil](/molmil-images/mine/8sel) | |
6Q2R
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![BU of 6q2r by Molmil](/molmil-images/mine/6q2r) | Cryo-EM structure of RET/GFRa2/NRTN extracellular complex in the tetrameric form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-2, ... | 著者 | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | 登録日 | 2019-08-08 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife, 8, 2019
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228L
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![BU of 228l by Molmil](/molmil-images/mine/228l) | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-06-25 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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8SEJ
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6DMY
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![BU of 6dmy by Molmil](/molmil-images/mine/6dmy) | Cryo-EM structure of human Ptch1 and ShhN complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yan, N, Gong, X, Qian, H.W. | 登録日 | 2018-06-05 | 公開日 | 2018-07-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science, 361, 2018
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6Q2J
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![BU of 6q2j by Molmil](/molmil-images/mine/6q2j) | Cryo-EM structure of extracellular dimeric complex of RET/GFRAL/GDF15 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-like, ... | 著者 | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | 登録日 | 2019-08-08 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife, 8, 2019
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