5WJL
 
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7DPM
 | | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | | 登録日 | 2020-12-20 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | | 主引用文献 | Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV.
Mabs, 13, 2021
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5WJN
 | | Crystal Structure of HLA-A*11:01-GTS3 | | 分子名称: | Beta-2-microglobulin, GTS3 peptide, HLA class I histocompatibility antigen, ... | | 著者 | Gras, S, Rossjohn, J. | | 登録日 | 2017-07-23 | | 公開日 | 2017-09-20 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
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6YIZ
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4G3K
 | | Crystal structure of a. aeolicus nlh1 gaf domain in an inactive state | | 分子名称: | Transcriptional regulator nlh1 | | 著者 | Wemmer, D.E, Batchelor, J.D, Wang, A, Lee, P, Doucleff, M. | | 登録日 | 2012-07-14 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus
J.Mol.Biol., 425, 2013
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4G3W
 | | Crystal structure of a. aeolicus nlh1 gaf domain in an inactive state | | 分子名称: | Transcriptional regulator nlh1 | | 著者 | Batchelor, J.D, Wang, A, Lee, P, Doucleff, M, Wemmer, D.E. | | 登録日 | 2012-07-15 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus
J.Mol.Biol., 425, 2013
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4G3V
 | | Crystal structure of A. Aeolicus nlh2 gaf domain in an inactive state | | 分子名称: | CHLORIDE ION, Transcriptional regulator nlh2 | | 著者 | Batchelor, J.D, Lee, P, Wang, A, Doucleff, M, Wemmer, D.E. | | 登録日 | 2012-07-15 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus
J.Mol.Biol., 425, 2013
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4RBW
 | | Crystal structure of human alpha-defensin 5, HD5 (Thr7Arg Glu21Arg mutant) | | 分子名称: | CHLORIDE ION, Defensin-5, SULFATE ION | | 著者 | Pazgier, M, Gohain, N, Tolbert, W.D. | | 登録日 | 2014-09-13 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Design of a potent antibiotic peptide based on the active region of human defensin 5.
J.Med.Chem., 58, 2015
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6SWA
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7X08
 | | S protein of SARS-CoV-2 in complex with 2G1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | 著者 | Guo, Y.Y, Zhang, Y.Y, Zhou, Q. | | 登録日 | 2022-02-21 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
Cell Discov, 8, 2022
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5W4R
 | | Structure of RORgt bound to a tertiary alcohol | | 分子名称: | 1-{4-[(R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]piperidin-1-yl}ethan-1-one, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J. | | 登録日 | 2017-06-12 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | | 主引用文献 | 6-Substituted quinolines as ROR gamma t inverse agonists.
Bioorg. Med. Chem. Lett., 27, 2017
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7C6P
 | | Bromodomain-containing 4 BD2 in complex with 3',4',7,8- Tetrahydroxyflavonoid | | 分子名称: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4 | | 著者 | Li, J, Yu, K, Luo, Y, Zheng, W, Liang, W, Zhu, J. | | 登録日 | 2020-05-22 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor.
J Enzyme Inhib Med Chem, 36, 2021
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7C2Z
 | | Bromodomain-containing 4 BD1 in complex with 3',4',7,8-Tetrahydroxyflavone | | 分子名称: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4, FORMIC ACID | | 著者 | Li, J, Zhu, J. | | 登録日 | 2020-05-10 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor.
J Enzyme Inhib Med Chem, 36, 2021
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5W4V
 | | Structure of RORgt bound to a tertiary alcohol | | 分子名称: | (R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanol, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J, Hars, U. | | 登録日 | 2017-06-13 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | 6-Substituted quinolines as ROR gamma t inverse agonists.
Bioorg. Med. Chem. Lett., 27, 2017
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8FE6
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8FE7
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8FUF
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6UF2
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4Z58
 | | HipB-O3 20mer complex | | 分子名称: | Antitoxin HipB, DNA (5'-D(*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*TP*AP*CP*GP*GP*GP*AP*TP*AP*A)-3') | | 著者 | Min, J, Brennan, R.G, Schumacher, M.A. | | 登録日 | 2015-04-02 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular mechanism on hipBA gene regulation.
To be published
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7LT3
 | | NHEJ Long-range synaptic complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... | | 著者 | He, Y, Chen, S. | | 登録日 | 2021-02-18 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis of long-range to short-range synaptic transition in NHEJ.
Nature, 593, 2021
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7OU1
 | | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MP2) | | 分子名称: | 1,2-ETHANEDIOL, L-asparaginase, ZINC ION | | 著者 | Imiolczyk, B, Loch, J.I, Gilski, M, Jaskolski, M. | | 登録日 | 2021-06-10 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
Nat Commun, 12, 2021
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7OZ6
 | | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MC) | | 分子名称: | DI(HYDROXYETHYL)ETHER, L-asparaginase, ZINC ION | | 著者 | Gilski, M, Loch, J.I, Imiolczyk, B, Jaskolski, M. | | 登録日 | 2021-06-25 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.757 Å) | | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
Nat Commun, 12, 2021
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7OS6
 | | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MP1) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... | | 著者 | Loch, J.I, Imiolczyk, B, Gilski, M, Jaskolski, M. | | 登録日 | 2021-06-07 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-04-26 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
Nat Commun, 12, 2021
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7OS3
 | | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV solved by S-SAD (orthorhombic form START) | | 分子名称: | CHLORIDE ION, L-asparaginase II protein, ZINC ION | | 著者 | Gilski, M, Loch, J.I, Imiolczyk, B, Jaskolski, M. | | 登録日 | 2021-06-07 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.177 Å) | | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
Nat Commun, 12, 2021
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7OS5
 | | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (orthorhombic form OP) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, L-asparaginase, ... | | 著者 | Loch, J.I, Imiolczyk, B, Gilski, M, Jaskolski, M. | | 登録日 | 2021-06-07 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.293 Å) | | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
Nat Commun, 12, 2021
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