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3V9R
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Crystal structure of Saccharomyces cerevisiae MHF complex
分子名称: SULFATE ION, Uncharacterized protein YDL160C-A, Uncharacterized protein YOL086W-A
著者Yang, H, Zhang, T, Zhong, C, Li, H, Zhou, J, Ding, J.
登録日2011-12-28
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Saccharomyces Cerevisiae MHF Complex Structurally Resembles the Histones (H3-H4)(2) Heterotetramer and Functions as a Heterotetramer
Structure, 20, 2012
4FWJ
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BU of 4fwj by Molmil
Native structure of LSD2/AOF1/KDM1b in spacegroup of I222 at 2.9A
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, PHOSPHATE ION, ...
著者Zhang, Q, Chen, Z.
登録日2012-07-01
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
6L1T
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BU of 6l1t by Molmil
Cryo-EM structure of phosphorylated Tyr39 a-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
登録日2019-09-30
公開日2020-08-12
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
6L1U
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BU of 6l1u by Molmil
Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
登録日2019-09-30
公開日2020-08-12
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
4FWE
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BU of 4fwe by Molmil
Native structure of LSD2 /AOF1/KDM1b in spacegroup of C2221 at 2.13A
分子名称: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ...
著者Zhang, Q, Chen, Z.
登録日2012-07-01
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
4FWF
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Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ...
著者Zhang, Q, Chen, Z.
登録日2012-07-01
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
4GB0
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BU of 4gb0 by Molmil
Crystal Structure of the RING domain of RNF168
分子名称: E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION
著者Zhang, X.Q, Wang, C.L, Zang, J.Y.
登録日2012-07-26
公開日2013-07-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for role of ring finger protein RNF168 RING domain
Cell Cycle, 12, 2013
5XYN
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The crystal structure of Csm2-Psy3-Shu1-Shu2 complex from budding yeast
分子名称: Chromosome segregation in meiosis protein 2, Platinum sensitivity protein 3, Suppressor of HU sensitivity involved in recombination protein 1, ...
著者Zhang, S, Zhang, T, Ding, J.
登録日2017-07-09
公開日2017-11-08
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for the functional role of the Shu complex in homologous recombination.
Nucleic Acids Res., 45, 2017
7YK2
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Cryo-EM structure of Apo-alpha-syn fibril
分子名称: Alpha-synuclein
著者Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
登録日2022-07-21
公開日2023-03-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7YK8
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Cryo-EM structure of dLAG3-alpha-syn fibril
分子名称: Alpha-synuclein
著者Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
登録日2022-07-22
公開日2023-03-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
8JEX
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Cryo-EM structure of alpha-synuclein gS87 fibril
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-synuclein, unverified amino acid chain
著者Xia, W.C, Sun, Y.P, Liu, C.
登録日2023-05-16
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures.
Nat Commun, 15, 2024
8JEY
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BU of 8jey by Molmil
Cryo-EM structure of alpha-synuclein pS87 fibril
分子名称: Alpha-synuclein
著者Xia, W.C, Sun, Y.P, Liu, C.
登録日2023-05-16
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures.
Nat Commun, 15, 2024
7V47
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Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V48
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Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V49
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Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO2
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Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO1
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BU of 7xo1 by Molmil
Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO0
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BU of 7xo0 by Molmil
Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO3
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Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
1V1I
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Adenovirus fibre shaft sequence N-terminally fused to the bacteriophage T4 fibritin foldon trimerisation motif with a long linker
分子名称: FIBRITIN, FIBER PROTEIN
著者Papanikolopoulou, K, Teixeira, S, Belrhali, H, Forsyth, V.T, Mitraki, A, van Raaij, M.J.
登録日2004-04-16
公開日2004-07-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Adenovirus Fibre Shaft Sequences Fold Into the Native Triple Beta-Spiral Fold When N-Terminally Fused to the Bacteriophage T4 Fibritin Foldon Trimerisation Motif
J.Mol.Biol., 342, 2004
1V1H
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BU of 1v1h by Molmil
Adenovirus fibre shaft sequence N-terminally fused to the bacteriophage T4 fibritin foldon trimerisation motif with a short linker
分子名称: FIBRITIN, FIBER PROTEIN
著者Papanikolopoulou, K, Teixeira, S, Belrhali, H, Forsyth, V.T, Mitraki, A, van Raaij, M.J.
登録日2004-04-16
公開日2004-07-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Adenovirus Fibre Shaft Sequences Fold Into the Native Triple Beta-Spiral Fold When N-Terminally Fused to the Bacteriophage T4 Fibritin Foldon Trimerisation Motif
J.Mol.Biol., 342, 2004
7XRP
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Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (localized refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C5G2 nanobody, Spike protein S1
著者Liu, L, Sun, H, Jiang, Y, Liu, X, Zhao, D, Zheng, Q, Li, S, Xia, N.
登録日2022-05-11
公開日2022-10-05
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode.
J Nanobiotechnology, 20, 2022
7YMN
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BU of 7ymn by Molmil
Cryo-EM structure of in vitro PHF fibril
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Li, X, Liu, C.
登録日2022-07-28
公開日2022-12-14
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022
7YPG
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Cryo-EM structure of amyloid fibril formed by tau (297-391)
分子名称: Isoform Tau-E of Microtubule-associated protein tau
著者Zhang, S.Q, Li, X, Liu, C.
登録日2022-08-03
公開日2022-12-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022
7Y47
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Crystal structure of bifunctional miltiradiene synthase from selaginella moellendorffii that complexed with GGPP
分子名称: Bifunctional diterpene synthase, chloroplastic, GERANYLGERANYL DIPHOSPHATE, ...
著者Ma, X, Tao, Y, Jiang, T.
登録日2022-06-14
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and mechanistic insights into the precise product synthesis by a bifunctional miltiradiene synthase.
Plant Biotechnol J, 21, 2023

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