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4GFX
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BU of 4gfx by Molmil
Crystal structure of the N-terminal domain of TXNIP
分子名称: GLYCEROL, Thioredoxin-interacting protein
著者Hwang, J, Kim, M.H.
登録日2012-08-04
公開日2014-02-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein.
Nat Commun, 5, 2014
4XGS
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BU of 4xgs by Molmil
Crystal structure analysis of novel iron uptake mechanism of Gram-negative bacterial ferritin
分子名称: Ferritin, GLYCEROL, HYDROXY DIIRON-OXO MOIETY, ...
著者Kim, S.
登録日2015-01-02
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Basis of Novel Iron-Uptake Route and Reaction Intermediates in Ferritins from Gram-Negative Bacteria
J. Mol. Biol., 428, 2016
6JLD
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BU of 6jld by Molmil
Crystal structure of a human ependymin related protein
分子名称: Mammalian ependymin-related protein 1
著者Park, S.Y.
登録日2019-03-05
公開日2019-07-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder.
Iucrj, 6, 2019
6JLA
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BU of 6jla by Molmil
Crystal structure of a mouse ependymin related protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Mammalian ependymin-related protein 1
著者Park, S.
登録日2019-03-04
公開日2020-03-04
最終更新日2020-09-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder.
Iucrj, 6, 2019
1KOZ
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BU of 1koz by Molmil
SOLUTION STRUCTURE OF OMEGA-GRAMMOTOXIN SIA
分子名称: Voltage-dependent Channel Inhibitor
著者Takeuchi, K, Park, E.J, Lee, C.W, Kim, J.I, Takahashi, H, Swartz, K.J, Shimada, I.
登録日2001-12-25
公開日2002-08-28
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel.
J.Mol.Biol., 321, 2002
4Z55
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BU of 4z55 by Molmil
Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
分子名称: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
著者Lee, C.C, Spraggon, G.
登録日2015-04-02
公開日2016-02-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
8D7M
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BU of 8d7m by Molmil
Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide
分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8D7O
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BU of 8d7o by Molmil
Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide
分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8D7P
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BU of 8d7p by Molmil
Human Casein kinase 1 delta in complex with phosphorylated Drosophila PERIOD peptide
分子名称: Casein kinase I isoform delta, Period circadian protein peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8D7N
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BU of 8d7n by Molmil
Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide
分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
6MKF
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BU of 6mkf by Molmil
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the imipenem-bound form
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, SULFATE ION, penicillin binding protein 5 (PBP5)
著者Moon, T.M, Lee, C, D'Andrea, E.D, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MKA
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BU of 6mka by Molmil
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the open conformation
分子名称: SULFATE ION, penicillin binding protein 5 (PBP5)
著者Moon, T.M, Lee, C, D'Andrea, E.D, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MKG
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BU of 6mkg by Molmil
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the benzylpenicilin-bound form
分子名称: OPEN FORM - PENICILLIN G, SULFATE ION, penicillin binding protein 5 (PBP5)
著者Moon, T.M, Lee, C, D'Andrea, E.D, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
2RGT
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BU of 2rgt by Molmil
Crystal Structure of Lhx3 LIM domains 1 and 2 with the binding domain of Isl1
分子名称: Fusion of LIM/homeobox protein Lhx3, linker, Insulin gene enhancer protein ISL-1, ...
著者Bhati, M, Lee, M, Guss, J.M, Matthews, J.M.
登録日2007-10-05
公開日2008-08-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.
Embo J., 27, 2008
2MBC
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BU of 2mbc by Molmil
Solution Structure of human holo-PRL-3 in complex with vanadate
分子名称: Protein tyrosine phosphatase type IVA 3
著者Jeong, K, Kang, D, Kim, J, Shin, S, Jin, B, Lee, C, Kim, E, Jeon, Y.H, Kim, Y.
登録日2013-07-29
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and backbone dynamics of vanadate-bound PRL-3: comparison of 15N nuclear magnetic resonance relaxation profiles of free and vanadate-bound PRL-3.
Biochemistry, 53, 2014
6KM6
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BU of 6km6 by Molmil
Human Carbonic Anhydrase II native 15 atm CO2
分子名称: CARBON DIOXIDE, Carbonic anhydrase 2, GLYCEROL, ...
著者Kim, C.U, Kim, J.K.
登録日2019-07-30
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase.
Iucrj, 7, 2020
6KM2
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BU of 6km2 by Molmil
Human Carbonic Anhydrase II V143I variant 15 atm CO2
分子名称: BICARBONATE ION, CARBON DIOXIDE, Carbonic anhydrase 2, ...
著者Kim, C.U, Kim, J.K.
登録日2019-07-30
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase.
Iucrj, 7, 2020
6KM4
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BU of 6km4 by Molmil
Human Carbonic Anhydrase II native 07 atm CO2
分子名称: CARBON DIOXIDE, Carbonic anhydrase 2, GLYCEROL, ...
著者Kim, C.U, Kim, J.K.
登録日2019-07-30
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase.
Iucrj, 7, 2020
6KM1
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BU of 6km1 by Molmil
Human Carbonic Anhydrase II V143I variant 13 atm CO2
分子名称: BICARBONATE ION, CARBON DIOXIDE, Carbonic anhydrase 2, ...
著者Kim, C.U, Kim, J.K.
登録日2019-07-30
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase.
Iucrj, 7, 2020
5D8D
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BU of 5d8d by Molmil
Crystal structure of D-alanine-D-alanine ligase from Acinetobacter baumannii
分子名称: D-alanine--D-alanine ligase
著者Huynh, K.H, Hong, M.K, Kang, L.W.
登録日2015-08-17
公開日2016-08-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The crystal structure of the D-alanine-D-alanine ligase from Acinetobacter baumannii suggests a flexible conformational change in the central domain before nucleotide binding
J. Microbiol., 53, 2015
5DMX
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BU of 5dmx by Molmil
Crystal structure of D-alanine-D-alanine ligase from Acinetobacter baumannii, space group p212121
分子名称: D-alanine--D-alanine ligase
著者Huynh, K.H, Hong, M.K, Kang, L.W.
登録日2015-09-09
公開日2016-08-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The crystal structure of the D-alanine-D-alanine ligase from Acinetobacter baumannii suggests a flexible conformational change in the central domain before nucleotide binding
J. Microbiol., 53, 2015
7Y1H
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BU of 7y1h by Molmil
Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1
分子名称: 1-(5-chloranyl-4-methyl-benzimidazol-1-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ...
著者Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y.
登録日2022-06-08
公開日2023-07-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023
7Y1W
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BU of 7y1w by Molmil
Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1
分子名称: (2R,3S)-2-[3-[4,5-bis(chloranyl)benzimidazol-1-yl]propyl]piperidin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ...
著者Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y.
登録日2022-06-09
公開日2023-07-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023
7Y28
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BU of 7y28 by Molmil
Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1
分子名称: 1-[6-(3-fluorophenyl)benzimidazol-1-yl]-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ...
著者Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y.
登録日2022-06-09
公開日2023-07-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023
7Y3S
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BU of 7y3s by Molmil
Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1
分子名称: 1-(6-bromanyl-7-methyl-imidazo[4,5-b]pyridin-3-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ...
著者Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y.
登録日2022-06-12
公開日2023-07-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023

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