2RGT

Crystal Structure of Lhx3 LIM domains 1 and 2 with the binding domain of Isl1

Summary for 2RGT

Entry DOI	10.2210/pdb2rgt/pdb
Descriptor	Fusion of LIM/homeobox protein Lhx3, linker, Insulin gene enhancer protein ISL-1, ZINC ION (3 entities in total)
Functional Keywords	protein-protein complex, lim domain, zn finger, activator, dna-binding, homeobox, metal-binding, nucleus, transcription, transcription regulation, metal binding protein
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	37729.67
Authors	Bhati, M.,Lee, M.,Guss, J.M.,Matthews, J.M. (deposition date: 2007-10-05, release date: 2008-08-12, Last modification date: 2024-03-13)
Primary citation	Bhati, M.,Lee, C.,Nancarrow, A.L.,Lee, M.,Craig, V.J.,Bach, I.,Guss, J.M.,Mackay, J.P.,Matthews, J.M. Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. Embo J., 27:2018-2029, 2008 Cited by PubMed: 18583962 DOI: 10.1038/emboj.2008.123 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation