2RGT

Crystal Structure of Lhx3 LIM domains 1 and 2 with the binding domain of Isl1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Fusion of LIM/homeobox protein Lhx3, linker, Insulin gene enhancer protein ISL-1	polymer	169	18603.2	2	UniProt (P50481) UniProt (P61372) Pfam (PF00412)	Mus musculus (Mouse)	LIM homeobox protein 3, Homeobox protein LIM-3, Homeobox protein P-LIM, Islet-1
2	C, D, E, F, G... (A, B)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
3	K, L (A, B)	water	water		18.0	48	Chemie (HOH)

Sequence modifications

A, B: 28 - 153 (UniProt: P50481)

PDB	External Database	Details
Gly 26	-	expression tag
Ser 27	-	expression tag

A, B: 262 - 291 (UniProt: P61372)
A, B: 154 - 164 (PDB: 2RGT)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37206.4
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	37729.7

*Water molecules are not included.