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5WVE
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BU of 5wve by Molmil
Apaf-1-Caspase-9 holoenzyme
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Caspase, ...
著者Li, Y, Zhou, M, Hu, Q, Shi, Y.
登録日2016-12-24
公開日2017-02-08
最終更新日2017-03-01
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6N1H
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BU of 6n1h by Molmil
Cryo-EM structure of ASC-CARD filament
分子名称: Apoptosis-associated speck-like protein containing a CARD
著者Li, Y, Fu, T, Wu, H.
登録日2018-11-08
公開日2018-12-05
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N1I
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BU of 6n1i by Molmil
Cryo-EM structure of NLRC4-CARD filament
分子名称: NLR family CARD domain-containing protein 4
著者Li, Y, Fu, T, Wu, H.
登録日2018-11-08
公開日2018-12-05
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6IMQ
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BU of 6imq by Molmil
Crystal structure of PML B1-box multimers
分子名称: CHLORIDE ION, Protein PML, ZINC ION
著者Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G.
登録日2018-10-23
公開日2019-07-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis.
Nat Commun, 10, 2019
6IUS
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BU of 6ius by Molmil
A higher kcat Rubisco
分子名称: Ribulose-1,5-bisphosphate carboxylase/oxygenase
著者Li, Y, Cai, Z.
登録日2018-11-30
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献A higher kcat Rubisco
To Be Published
8JNS
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BU of 8jns by Molmil
cryo-EM structure of a CED-4 hexamer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 4, MAGNESIUM ION
著者Li, Y, Shi, Y.
登録日2023-06-06
公開日2023-06-28
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into CED-3 activation.
Life Sci Alliance, 6, 2023
8JO0
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BU of 8jo0 by Molmil
The Cryo-EM structure of a heptameric CED-4/CED-3 catalytic complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 4, MAGNESIUM ION
著者Li, Y, Shi, Y.
登録日2023-06-06
公開日2023-06-28
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into CED-3 activation.
Life Sci Alliance, 6, 2023
6H8Q
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BU of 6h8q by Molmil
Structural basis for Scc3-dependent cohesin recruitment to chromatin
分子名称: Cohesin subunit SCC3, DNA (5'-D(P*CP*TP*TP*TP*CP*GP*TP*TP*TP*CP*CP*TP*TP*GP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*CP*AP*AP*GP*GP*AP*AP*AP*CP*GP*AP*AP*AP*G)-3'), ...
著者Li, Y, Muir, K, Panne, D.
登録日2018-08-03
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.631 Å)
主引用文献Structural basis for Scc3-dependent cohesin recruitment to chromatin.
Elife, 7, 2018
7WN8
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BU of 7wn8 by Molmil
Crystal structure of antibody (BC31M5) binds to CD47
分子名称: BC31M5 Fab Heavy chain, BC31M5 Fab Light chain, Leukocyte surface antigen CD47, ...
著者Li, Y, Wang, W, Sui, J, Zhang, S.
登録日2022-01-17
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety.
J Hematol Oncol, 16, 2023
5YDM
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BU of 5ydm by Molmil
The crystal structure of the Acyl Transferase domain of SpnD complex with benzylmalonyl
分子名称: (2R)-2-methanoyl-3-phenyl-propanoic acid, PKS
著者Li, Y, Qu, X.D, Zhou, J.H.
登録日2017-09-13
公開日2018-05-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin.
Angew. Chem. Int. Ed. Engl., 57, 2018
5YDL
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BU of 5ydl by Molmil
The crystal structure of the Acyl Transferase domain of SpnD complex with 2-(pent-4-yn-1-yl)malonyl
分子名称: (2R)-2-methanoylhept-6-ynoic acid, PKS
著者Li, Y, Qu, X.D, Zhou, J.H.
登録日2017-09-13
公開日2018-05-23
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin.
Angew. Chem. Int. Ed. Engl., 57, 2018
7E7C
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BU of 7e7c by Molmil
Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27
分子名称: 1,2-ETHANEDIOL, Histone H3K27ac(24-27) peptide, IODIDE ION, ...
著者Li, Y, Li, H.
登録日2021-02-25
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27
To Be Published
5YDA
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BU of 5yda by Molmil
The crystal structure of the Acyl Transferase domain of SpnD
分子名称: PKS
著者Li, Y, Qu, X.D, Zhou, J.H.
登録日2017-09-12
公開日2018-05-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.353 Å)
主引用文献Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin.
Angew. Chem. Int. Ed. Engl., 57, 2018
5VZT
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BU of 5vzt by Molmil
Crystal structure of the Skp1-FBXO31 complex
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, F-box only protein 31, PHOSPHATE ION, ...
著者Li, Y, Jin, K, Hao, B.
登録日2017-05-29
公開日2018-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7UR2
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BU of 7ur2 by Molmil
Crystal structure of the Sec14 domain of the RhoGEF Kalirin
分子名称: Isoform 7 of Kalirin, SULFATE ION
著者Li, Y, Doukov, T.I, Hao, B.
登録日2022-04-21
公開日2023-01-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure of the Sec14 domain of Kalirin reveals a distinct class of lipid-binding module in RhoGEFs.
Nat Commun, 14, 2023
5VZU
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BU of 5vzu by Molmil
Crystal structure of the Skp1-FBXO31-cyclin D1 complex
分子名称: Cyclin D1, F-box only protein 31, PHOSPHATE ION, ...
著者Li, Y, Jin, K, Hao, B.
登録日2017-05-29
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7E7A
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BU of 7e7a by Molmil
Crystal structure of apo ENL YEATS domain T3 mutant
分子名称: Protein ENL
著者Li, Y, Li, H.
登録日2021-02-25
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27
To Be Published
7CWW
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BU of 7cww by Molmil
Crystal structure of TsrL
分子名称: 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, TsrE
著者Li, Y, Pan, L.F.
登録日2020-08-31
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献crystal structure of TsrL
To Be Published
7F68
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BU of 7f68 by Molmil
Crystal structure of N-ras S89D
分子名称: GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Li, Y, Sun, Q.
登録日2021-06-24
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Crystal structure of N-ras S89D
To Be Published
6ZD4
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BU of 6zd4 by Molmil
Crystal structure of YTHDC1 S378A mutant
分子名称: SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD3
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BU of 6zd3 by Molmil
Crystal structure of YTHDC1 M438A mutant
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD5
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BU of 6zd5 by Molmil
Crystal structure of YTHDC1 S378A mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZDA
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BU of 6zda by Molmil
Crystal structure of YTHDC1 M438A mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTHDC1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-14
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD8
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BU of 6zd8 by Molmil
Crystal structure of YTHDC1 T379V mutant
分子名称: SULFATE ION, YTHDC1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-14
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6DWO
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BU of 6dwo by Molmil
Crystal structure of alpha-1-2-mannosidase from Enterococcus faecalis V583
分子名称: ACETATE ION, Alpha-1,2-mannosidase, CALCIUM ION, ...
著者Fisher, A.J, Li, Y.
登録日2018-06-26
公開日2019-10-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Enterococcus faecalis alpha 1-2-mannosidase (EfMan-I): an efficient catalyst for glycoprotein N-glycan modification.
Febs Lett., 594, 2020

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