6H21
 
 | | TarP-UDP-GlcNAc-Mn | | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Guo, Y, Stehle, T. | | 登録日 | 2018-07-12 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
|
|
4TRA
 | |
4Z1I
 | | Crystal structure of human Trap1 with AMPPNP | | 分子名称: | Heat shock protein 75 kDa, mitochondrial, MAGNESIUM ION, ... | | 著者 | Lee, C, Park, H.K, Ryu, J.H, Kang, B.H. | | 登録日 | 2015-03-27 | | 公開日 | 2015-04-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
|
|
4Z1G
 | | Crystal structure of human Trap1 with BIIB-021 | | 分子名称: | 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, Heat shock protein 75 kDa, mitochondrial | | 著者 | Lee, C, Park, H.K, Ryu, J.H, Kang, B.H. | | 登録日 | 2015-03-27 | | 公開日 | 2015-04-22 | | 最終更新日 | 2022-10-05 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
|
|
4Z1F
 | | Crystal structure of human Trap1 with PU-H71 | | 分子名称: | 8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE, Heat shock protein 75 kDa, mitochondrial | | 著者 | Lee, C, Park, H.K, Ryu, J.H, Kang, B.H. | | 登録日 | 2015-03-27 | | 公開日 | 2015-04-22 | | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | | 主引用文献 | Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
|
|
4Z1H
 | | Crystal structure of human Trap1 with SMTIN-P01 | | 分子名称: | 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[6-(triphenyl-lambda~5~-phosphanyl)hexyl]-9H-purin-6-amine, Heat shock protein 75 kDa, mitochondrial | | 著者 | Lee, C, Park, H.K, Ryu, J.H, Kang, B.H. | | 登録日 | 2015-03-27 | | 公開日 | 2015-04-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
|
|
2PYY
 | | Crystal Structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with (L)-glutamate | | 分子名称: | GLUTAMIC ACID, Ionotropic glutamate receptor bacterial homologue | | 著者 | Lee, J.H, Kang, G.B, Lim, H.-H, Ree, M, Park, C.-S, Eom, S.H. | | 登録日 | 2007-05-17 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with L-glutamate: structural dissection of the ligand interaction and subunit interface.
J.Mol.Biol., 376, 2008
|
|
3L0V
 | |
3L0T
 | | Crystal structure of catalytic domain of TACE with hydantoin inhibitor | | 分子名称: | Disintegrin and metalloproteinase domain-containing protein 17, ISOPROPYL ALCOHOL, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ... | | 著者 | Orth, P. | | 登録日 | 2009-12-10 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Discovery and SAR of hydantoin TACE inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
|
|
3LEA
 | |
1G5S
 | | CRYSTAL STRUCTURE OF HUMAN CYCLIN DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH THE INHIBITOR H717 | | 分子名称: | 2-[TRANS-(4-AMINOCYCLOHEXYL)AMINO]-6-(BENZYL-AMINO)-9-CYCLOPENTYLPURINE, CELL DIVISION PROTEIN KINASE 2 | | 著者 | Dreyer, M.K, Borcherding, D.R, Dumont, J.A, Peet, N.P, Tsay, J.T, Wright, P.S, Bitonti, A.J, Shen, J, Kim, S.-H. | | 登録日 | 2000-11-02 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Crystal structure of human cyclin-dependent kinase 2 in complex with the adenine-derived inhibitor H717.
J.Med.Chem., 44, 2001
|
|
1FJS
 | | CRYSTAL STRUCTURE OF THE INHIBITOR ZK-807834 (CI-1031) COMPLEXED WITH FACTOR XA | | 分子名称: | CALCIUM ION, CHLORIDE ION, COAGULATION FACTOR XA, ... | | 著者 | Adler, M, Whitlow, M. | | 登録日 | 2000-08-08 | | 公開日 | 2000-10-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Preparation, characterization, and the crystal structure of the inhibitor ZK-807834 (CI-1031) complexed with factor Xa.
Biochemistry, 39, 2000
|
|
4ZYA
 | | The N-terminal extension domain of human asparaginyl-tRNA synthetase | | 分子名称: | Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ... | | 著者 | Park, J.S, Park, M.C, Goughnour, P, Kim, H.S, Kim, S.J, Kim, H.J, Kim, S.H, Han, B.W. | | 登録日 | 2015-05-21 | | 公開日 | 2016-05-25 | | 最終更新日 | 2019-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.
Int. J. Biol. Macromol., 120, 2018
|
|
3BCC
 | | STIGMATELLIN AND ANTIMYCIN BOUND CYTOCHROME BC1 COMPLEX FROM CHICKEN | | 分子名称: | ANTIMYCIN, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.-I, Kim, K.K, Hung, L.-W, Crofts, A.R, Berry, E.A, Kim, S.-H. | | 登録日 | 1998-03-23 | | 公開日 | 1998-08-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Electron transfer by domain movement in cytochrome bc1.
Nature, 392, 1998
|
|
1LFD
 | | CRYSTAL STRUCTURE OF THE ACTIVE RAS PROTEIN COMPLEXED WITH THE RAS-INTERACTING DOMAIN OF RALGDS | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RALGDS, ... | | 著者 | Huang, L, Hofer, F, Martin, G.S, Kim, S.-H. | | 登録日 | 1998-04-29 | | 公開日 | 1999-05-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the interaction of Ras with RalGDS.
Nat.Struct.Biol., 5, 1998
|
|
1STZ
 | | Crystal structure of a hypothetical protein at 2.2 A resolution | | 分子名称: | Heat-inducible transcription repressor hrcA homolog | | 著者 | Liu, J, Adams, P.D, Shin, D.-H, Huang, C, Yokota, H, Jancarik, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2004-03-25 | | 公開日 | 2004-08-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a heat-inducible transcriptional repressor HrcA from Thermotoga maritima: structural insight into DNA binding and dimerization.
J.Mol.Biol., 350, 2005
|
|
2RDB
 | | X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase I100W Mutant | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, FE (III) ION, GLYCEROL, ... | | 著者 | Murray, L.J, Garcia-Serres, R, McCormick, M.S, Davydov, R, Naik, S, Hoffman, B.M, Huynh, B.H, Lippard, S.J. | | 登録日 | 2007-09-21 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dioxygen activation at non-heme diiron centers: oxidation of a proximal residue in the I100W variant of toluene/o-xylene monooxygenase hydroxylase.
Biochemistry, 46, 2007
|
|
1NYE
 | | Crystal structure of OsmC from E. coli | | 分子名称: | Osmotically inducible protein C | | 著者 | Shin, D.H, Choi, I.-G, Busso, D, Jancarik, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2003-02-12 | | 公開日 | 2004-03-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of OsmC from Escherichia coli: a salt-shock-induced protein.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
1QU7
 | |
4LVH
 | | Insight into highly conserved H1 subtype-specific epitopes in influenza virus hemagglutinin | | 分子名称: | CALCIUM ION, Hemagglutinin, MONOCLONAL ANTIBODY H-CHAIN, ... | | 著者 | Kim, K.H, Cho, K.J, Kim, S, Seok, J.H, Lee, J.-H. | | 登録日 | 2013-07-26 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Insight into highly conserved h1 subtype-specific epitopes in influenza virus hemagglutinin
Plos One, 9, 2014
|
|
5CHI
 | |
1S7O
 | | Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes | | 分子名称: | Hypothetical UPF0122 protein SPy1201/SpyM3_0842/SPs1042/spyM18_1152 | | 著者 | Oganesyan, V, Pufan, R, DeGiovanni, A, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2004-01-29 | | 公開日 | 2004-06-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
7RS3
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-29 | | 分子名称: | (1S,2R,4S)-6-[4-(benzyloxy)phenyl]-5-(4-hydroxyphenyl)-N-(4-methoxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, CYSTEINE, Estrogen receptor, ... | | 著者 | Min, J, Nwachukwu, J.C, Min, C.K, Njeri, J.W, Srinivasan, S, Rangarajan, E.S, Nettles, C.C, Yan, S, Houtman, R, Griffin, P.R, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2021-08-10 | | 公開日 | 2021-09-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Dual-mechanism estrogen receptor inhibitors.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7RS0
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-18 | | 分子名称: | (1R,2S,4R,5R,6R)-5-(4-hydroxyphenyl)-N-(4-methoxyphenyl)-6-(4-propoxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]heptane-2-sulfonamide, Estrogen receptor | | 著者 | Min, J, Nwachukwu, J.C, Min, C.K, Njeri, J.W, Srinivasan, S, Rangarajan, E.S, Nettles, C.C, Yan, S, Houtman, R, Griffin, P.R, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2021-08-10 | | 公開日 | 2021-09-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Dual-mechanism estrogen receptor inhibitors.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7RS1
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-21 | | 分子名称: | Estrogen receptor, methyl 3-(4-{[(1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonyl](2,2,2-trifluoroethyl)amino}phenyl)prop-2-enoate | | 著者 | Min, J, Nwachukwu, J.C, Min, C.K, Njeri, J.W, Srinivasan, S, Rangarajan, E.S, Nettles, C.C, Yan, S, Houtman, R, Griffin, P.R, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2021-08-10 | | 公開日 | 2021-09-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Dual-mechanism estrogen receptor inhibitors.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
