1FJS

CRYSTAL STRUCTURE OF THE INHIBITOR ZK-807834 (CI-1031) COMPLEXED WITH FACTOR XA

Summary for 1FJS

• Entry DOI: 10.2210/pdb1fjs/pdb
• Related: 1FAX 1HCG 1QB1 1QBN 1XKA 1XKB
• Descriptor: COAGULATION FACTOR XA, CALCIUM ION, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: protein inhibitor complex, coagulation cofactor, protease, blood clotting
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 33190.93

Authors

Adler, M.,Whitlow, M. (deposition date: 2000-08-08, release date: 2000-10-04, Last modification date: 2024-03-13)

• Primary citation: Adler, M.,Davey, D.D.,Phillips, G.B.,Kim, S.H.,Jancarik, J.,Rumennik, G.,Light, D.R.,Whitlow, M.; Preparation, characterization, and the crystal structure of the inhibitor ZK-807834 (CI-1031) complexed with factor Xa.; Biochemistry, 39:12534-12542, 2000; PubMed: 11027132; DOI: 10.1021/bi001477q

Experimental method

X-RAY DIFFRACTION (1.92 Å)