5OH4
 
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Piperidine-2,6-dione (Glutarimide) | | 分子名称: | Cereblon isoform 4, ZINC ION, piperidine-2,6-dione | | 著者 | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | 登録日 | 2017-07-14 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Chemical Ligand Space of Cereblon.
Acs Omega, 3, 2018
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5OH2
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Pyrrolidin-2-one (Butyrolactam) | | 分子名称: | Cereblon isoform 4, ZINC ION, pyrrolidin-2-one | | 著者 | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | 登録日 | 2017-07-14 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Chemical Ligand Space of Cereblon.
Acs Omega, 3, 2018
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6FJU
 | | Rpn11 homolog from Caldiarchaeum Subterraneum | | 分子名称: | 26S proteasome regulatory subunit N11-like protein, SULFATE ION, ZINC ION | | 著者 | Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. | | 登録日 | 2018-01-23 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system.
Nat Commun, 9, 2018
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6FJ7
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6FES
 | | Crystal structure of novel repeat protein BRIC2 fused to DARPin D12 | | 分子名称: | 1,2-ETHANEDIOL, D12_BRIC2, a synthetic protein,D12_BRIC2, ... | | 著者 | ElGamacy, M, Coles, M, Ernst, P, Zhu, H, Hartmann, M.D, Plueckthun, A, Lupas, A. | | 登録日 | 2018-01-03 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture.
ACS Synth Biol, 7, 2018
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6FJV
 | | Rpn11 homolog from Caldiarchaeum Subterraneum, truncated | | 分子名称: | 26S proteasome regulatory subunit N11-like protein, SULFATE ION | | 著者 | Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. | | 登録日 | 2018-01-23 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system.
Nat Commun, 9, 2018
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6FF6
 | | Crystal structure of novel repeat protein BRIC1 | | 分子名称: | BRIC1 | | 著者 | ElGamacy, M, Coles, M, Ernst, P, Zhu, H, Hartmann, M.D, Plueckthun, A, Lupas, A.N. | | 登録日 | 2018-01-03 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture.
ACS Synth Biol, 7, 2018
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6FNN
 | | Caldiarchaeum Subterraneum Ubiquitin:Rpn11-homolog complex | | 分子名称: | 26S proteasome regulatory subunit N11-like protein, SULFATE ION, Ubiquitin-like protein, ... | | 著者 | Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. | | 登録日 | 2018-02-04 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system.
Nat Commun, 9, 2018
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6FNO
 | | Caldiarchaeum Subterraneum Ubiquitin:Rpn11-homolog complex, zinc soak | | 分子名称: | 26S proteasome regulatory subunit N11-like protein, SULFATE ION, Ubiquitin-like protein, ... | | 著者 | Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. | | 登録日 | 2018-02-04 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system.
Nat Commun, 9, 2018
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9EZZ
 | | Bacterial histone protein HBb from Bdellovibrio bacteriovorus bound to DNA | | 分子名称: | DNA (5'-D(P*AP*GP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*CP*T)-3'), PHOSPHATE ION, ... | | 著者 | Hu, Y, Albrecht, R, Hartmann, M.D. | | 登録日 | 2024-04-14 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending.
Nucleic Acids Res., 52, 2024
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9F0E
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9F2C
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6R0V
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6R0U
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 5a and hydrolysis product | | 分子名称: | 3-azanyl-2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]benzoic acid, 4-azanyl-2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]isoindole-1,3-dione, CHLORIDE ION, ... | | 著者 | Heim, C, Hartmann, M.D. | | 登録日 | 2019-03-13 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
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6R0S
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 4a and hydrolysis product | | 分子名称: | 2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-4-nitro-isoindole-1,3-dione, 2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]-6-nitro-benzoic acid, CEREBLON ISOFORM 4, ... | | 著者 | Heim, C, Hartmann, M.D. | | 登録日 | 2019-03-13 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
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6R0Q
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6R11
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 5b | | 分子名称: | 5-azanyl-2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]isoindole-1,3-dione, CHLORIDE ION, Cereblon isoform 4, ... | | 著者 | Heim, C, Hartmann, M.D. | | 登録日 | 2019-03-13 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
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6R13
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6R12
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6R18
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6R19
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6R1A
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6R1D
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6R1K
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6R1W
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