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7RKY
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BU of 7rky by Molmil
Binding mode of US27-Gi-scFv16 in OCL-state
分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, GUANOSINE-5'-DIPHOSPHATE, ...
著者Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKN
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BU of 7rkn by Molmil
Structure of CX3CL1-US28-Gi-scFv16 in OC-state
分子名称: Antibody fragment scFv16, Fractalkine, G-protein coupled receptor homolog US28, ...
著者Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKM
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BU of 7rkm by Molmil
Structure of CX3CL1-US28-Gi-scFv16 in C-state
分子名称: Antibody fragment scFv16, CHOLESTEROL, Fractalkine, ...
著者Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKX
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BU of 7rkx by Molmil
Structure of US27-Gi-scFv16 in CL-state
分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RAA
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BU of 7raa by Molmil
Designed StabIL-2 seq15
分子名称: Interleukin-2, MAGNESIUM ION
著者Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C.
登録日2021-06-30
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Interleukin-2 superkines by computational design.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RKF
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BU of 7rkf by Molmil
Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody fragment scFv16, Fractalkine, ...
著者Tsutsumi, N, Maeda, S, Qu, Q, Skiniotis, G, Kobilka, B.K, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
3E2H
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BU of 3e2h by Molmil
Structure of the m67 high-affinity mutant of the 2C TCR in complex with Ld/QL9
分子名称: H-2 class I histocompatibility antigen, L-D alpha chain, M67 TCR beta chain, ...
著者Colf, L.A, Garcia, K.C.
登録日2008-08-05
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation
J.Immunol., 181, 2008
3E3Q
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BU of 3e3q by Molmil
Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9
分子名称: H-2 class I histocompatibility antigen, L-D alpha chain, QL9 peptide, ...
著者Colf, L.A, Garcia, K.C.
登録日2008-08-07
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation.
J.Immunol., 181, 2008
3EEB
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BU of 3eeb by Molmil
Structure of the V. cholerae RTX cysteine protease domain
分子名称: INOSITOL HEXAKISPHOSPHATE, RTX toxin RtxA, SODIUM ION
著者Lupardus, P.J, Shen, A, Bogyo, M, Garcia, K.C.
登録日2008-09-04
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain
Science, 322, 2008
3DUH
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BU of 3duh by Molmil
Structure of Interleukin-23
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit beta, Interleukin-23 subunit alpha
著者Lupardus, P.J, Garcia, K.C.
登録日2008-07-17
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12.
J.Mol.Biol., 382, 2008
3E0G
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BU of 3e0g by Molmil
Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leukemia inhibitory factor receptor, ...
著者Lupardus, P.J, Garcia, K.C.
登録日2008-07-31
公開日2008-09-23
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex.
Mol.Cell, 31, 2008
3GCD
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BU of 3gcd by Molmil
Structure of the V. cholerae RTX cysteine protease domain in complex with an aza-Leucine peptide inhibitor
分子名称: INOSITOL HEXAKISPHOSPHATE, RTX toxin RtxA, SODIUM ION, ...
著者Lupardus, P.J, Garcia, K.C, Shen, A, Bogyo, M.
登録日2009-02-21
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin.
Nat.Chem.Biol., 5, 2009
8CX4
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BU of 8cx4 by Molmil
TCR-antigen complex AS8.4-YEIH-HLA*B27
分子名称: AS8.4a, AS8.4b, Beta-2-microglobulin, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2022-05-19
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
8DH9
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BU of 8dh9 by Molmil
Leptin-bound leptin receptor complex-D3-D7
分子名称: Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
8DH8
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BU of 8dh8 by Molmil
Leptin-bound leptin receptor complex-full ECD
分子名称: Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
8DHA
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BU of 8dha by Molmil
Leptin-bound leptin receptor complex- focused interaction
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
8DA7
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BU of 8da7 by Molmil
Coevolved affibody-Z domain pair LL1.c6
分子名称: Immunoglobulin G-binding protein A, MALONATE ION, affibody LL1.FIFV
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA8
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BU of 8da8 by Molmil
Coevolved affibody-Z domain pair LL2.c1
分子名称: Affibody LL2.FIIK, GLYCEROL, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA9
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BU of 8da9 by Molmil
Coevolved affibody-Z domain pair LL2.c3
分子名称: Affibody LL2.FIIV, GLYCEROL, Immunoglobulin G-binding protein A, ...
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DAC
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BU of 8dac by Molmil
Coevolved affibody-Z domain pair LL2.c22
分子名称: Affibody LL2.FILV, GLYCEROL, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA3
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BU of 8da3 by Molmil
Coevolved affibody-Z domain pair LL1.c1
分子名称: Affibody LL1.FILF, Immunoglobulin G-binding protein A, MALONATE ION, ...
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA4
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BU of 8da4 by Molmil
Coevolved affibody-Z domain pair LL1.c2
分子名称: Affibody LL1.FIVM, Immunoglobulin G-binding protein A, SULFATE ION, ...
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DAB
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BU of 8dab by Molmil
Coevolved affibody-Z domain pair LL2.c17
分子名称: Affibody LL2.IVVY, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.134 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA6
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BU of 8da6 by Molmil
Coevolved affibody-Z domain pair LL1.c5
分子名称: Affibody LL1.FIIM, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA5
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BU of 8da5 by Molmil
Coevolved affibody-Z domain pair LL1.c4
分子名称: GLYCEROL, Immunoglobulin G-binding protein A, affibody LL1.FIVM
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023

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