Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6MOL
DownloadVisualize
BU of 6mol by Molmil
Monoextended DARPin M_R12 complex with EpoR
分子名称: Erythropoietin receptor, GLYCEROL, Monoextended DARPin R12 (M_R12)
著者Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y.
登録日2018-10-04
公開日2019-06-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.163 Å)
主引用文献Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOF
DownloadVisualize
BU of 6mof by Molmil
Monomeric DARPin G2 complex with EpoR
分子名称: 1,2-ETHANEDIOL, Erythropoietin receptor, G2 DARPin
著者Jude, K.M, Mohan, K, Garcia, K.C.
登録日2018-10-04
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6NE2
DownloadVisualize
BU of 6ne2 by Molmil
Designed repeat protein in complex with Fz7
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Miao, Y, Jude, K.M, Garcia, K.C.
登録日2018-12-15
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
6NE1
DownloadVisualize
BU of 6ne1 by Molmil
Designed repeat protein in complex with Fz4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Pfs, ...
著者Miao, Y, Jude, K.M, Garcia, K.C.
登録日2018-12-15
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.011 Å)
主引用文献Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
6NE4
DownloadVisualize
BU of 6ne4 by Molmil
Designed repeat protein specifically in complex with Fz7CRD
分子名称: 1,2-ETHANEDIOL, Designed repeat binding protein, Frizzled-7, ...
著者Miao, Y, Jude, K.M, Garcia, K.C.
登録日2018-12-16
公開日2019-05-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.648 Å)
主引用文献Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
6NDZ
DownloadVisualize
BU of 6ndz by Molmil
Designed repeat protein in complex with Fz8
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ACETIC ACID, ...
著者Miao, Y, Jude, K.M, Garcia, K.C.
登録日2018-12-14
公開日2019-05-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.264 Å)
主引用文献Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
2GYZ
DownloadVisualize
BU of 2gyz by Molmil
Crystal structure of human artemin
分子名称: neurotrophic factor artemin isoform 3
著者Wang, X.Q, Garcia, K.C.
登録日2006-05-10
公開日2006-06-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors.
Structure, 14, 2006
2H3N
DownloadVisualize
BU of 2h3n by Molmil
Crystal structure of a surrogate light chain (LAMBDA5 and VpreB) homodimer
分子名称: Ig lambda-5, VpreB protein
著者Bankovich, A.J, Garcia, K.C.
登録日2006-05-22
公開日2007-05-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insight into pre-B cell receptor function
Science, 316, 2007
2IFG
DownloadVisualize
BU of 2ifg by Molmil
Structure of the extracellular segment of human TRKA in complex with nerve growth factor
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, High affinity nerve growth factor receptor, ...
著者He, X, Garcia, K.C.
登録日2006-09-20
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.
Neuron, 53, 2007
7RA9
DownloadVisualize
BU of 7ra9 by Molmil
Designed StabIL-2 seq1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Interleukin-2, PHOSPHATE ION
著者Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C.
登録日2021-06-30
公開日2022-03-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interleukin-2 superkines by computational design.
Proc.Natl.Acad.Sci.USA, 119, 2022
3TJH
DownloadVisualize
BU of 3tjh by Molmil
42F3-p3A1/H2-Ld complex
分子名称: 42F3 alpha, 42F3 beta, H2-Ld SBM2, ...
著者Adams, J.J, Kruse, A, Kranz, D.M, Garcia, K.C.
登録日2011-08-24
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3S8W
DownloadVisualize
BU of 3s8w by Molmil
D2 domain of human IFNAR2
分子名称: CHLORIDE ION, Interferon alpha/beta receptor 2
著者Thomas, C, Garcia, K.C.
登録日2011-05-31
公開日2011-08-31
最終更新日2012-03-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
3E3Q
DownloadVisualize
BU of 3e3q by Molmil
Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9
分子名称: H-2 class I histocompatibility antigen, L-D alpha chain, QL9 peptide, ...
著者Colf, L.A, Garcia, K.C.
登録日2008-08-07
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation.
J.Immunol., 181, 2008
7S2R
DownloadVisualize
BU of 7s2r by Molmil
nanobody bound to IL-2Rg
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ...
著者Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C.
登録日2021-09-03
公開日2022-03-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
7S2S
DownloadVisualize
BU of 7s2s by Molmil
nanobody bound to Interleukin-2Rbeta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IL2Rb-binding nanobody, Interleukin-2 receptor subunit beta, ...
著者Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C.
登録日2021-09-03
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
2RKC
DownloadVisualize
BU of 2rkc by Molmil
Crystal structure of the measles virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Colf, L.A, Juo, Z.S, Garcia, K.C.
登録日2007-10-16
公開日2007-11-20
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the measles virus hemagglutinin: implications for host cell receptor attachment.
To be Published
3EEB
DownloadVisualize
BU of 3eeb by Molmil
Structure of the V. cholerae RTX cysteine protease domain
分子名称: INOSITOL HEXAKISPHOSPHATE, RTX toxin RtxA, SODIUM ION
著者Lupardus, P.J, Shen, A, Bogyo, M, Garcia, K.C.
登録日2008-09-04
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain
Science, 322, 2008
3TFK
DownloadVisualize
BU of 3tfk by Molmil
42F3-p4B10/H2-Ld
分子名称: 42F3 alpha, 42F3 beta, H2-Ld SBM2, ...
著者Adams, J.J, Kranz, D.M, Garcia, K.C.
登録日2011-08-15
公開日2011-12-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3DUH
DownloadVisualize
BU of 3duh by Molmil
Structure of Interleukin-23
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit beta, Interleukin-23 subunit alpha
著者Lupardus, P.J, Garcia, K.C.
登録日2008-07-17
公開日2008-08-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12.
J.Mol.Biol., 382, 2008
3E2H
DownloadVisualize
BU of 3e2h by Molmil
Structure of the m67 high-affinity mutant of the 2C TCR in complex with Ld/QL9
分子名称: H-2 class I histocompatibility antigen, L-D alpha chain, M67 TCR beta chain, ...
著者Colf, L.A, Garcia, K.C.
登録日2008-08-05
公開日2008-11-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation
J.Immunol., 181, 2008
3E0G
DownloadVisualize
BU of 3e0g by Molmil
Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leukemia inhibitory factor receptor, ...
著者Lupardus, P.J, Garcia, K.C.
登録日2008-07-31
公開日2008-09-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex.
Mol.Cell, 31, 2008
3TF7
DownloadVisualize
BU of 3tf7 by Molmil
42F3 QL9/H2-Ld complex
分子名称: 42F3 Mut7 scFv (42F3 alpha chain, linker, 42F3 beta chain), ...
著者Adams, J.J, Kranz, D.M, Garcia, K.C.
登録日2011-08-15
公開日2011-12-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3TPU
DownloadVisualize
BU of 3tpu by Molmil
42F3 p5E8/H2-Ld complex
分子名称: 1,2-ETHANEDIOL, 42F3 alpha, 42F3 beta, ...
著者Adams, J.J, Kranz, D.M, Garcia, K.C.
登録日2011-09-08
公開日2011-12-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
5E4E
DownloadVisualize
BU of 5e4e by Molmil
Engineered Interleukin-13 bound to receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ...
著者Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C.
登録日2015-10-05
公開日2015-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci.Signal., 8, 2015
5EO9
DownloadVisualize
BU of 5eo9 by Molmil
Crystal Structure of the complex of Dpr6 Domain 1 bound to DIP-alpha Domain 1+2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CG32791, isoform A, ...
著者Ozkan, E, Zinn, K, Garcia, K.C.
登録日2015-11-10
公開日2016-01-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2988 Å)
主引用文献Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins.
Cell, 163, 2015

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon