3E2H

Structure of the m67 high-affinity mutant of the 2C TCR in complex with Ld/QL9

Summary for 3E2H

• Entry DOI: 10.2210/pdb3e2h/pdb
• Related: 3E3Q
• Descriptor: H-2 class I histocompatibility antigen, L-D alpha chain, QL9 PEPTIDE, T-cell receptor alpha chain V region PHDS58, ... (4 entities in total)
• Functional Keywords: tcr, mhc, cross-reactivity, high affinity, glycoprotein, immune response, membrane, mhc i, phosphoprotein, transmembrane, immunoglobulin domain, receptor, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01897
• Total number of polymer chains: 4
• Total formula weight: 45726.60

Authors

Colf, L.A.,Garcia, K.C. (deposition date: 2008-08-05, release date: 2008-11-04, Last modification date: 2023-08-30)

• Primary citation: Jones, L.L.,Colf, L.A.,Stone, J.D.,Garcia, K.C.,Kranz, D.M.; Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation; J.Immunol., 181:6255-6264, 2008; PubMed: 18941216

Experimental method

X-RAY DIFFRACTION (3.8 Å)