1EPR
 
 | | ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-135,040 | | 分子名称: | ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide | | 著者 | Badasso, M, Crawford, M, Cooper, J.B, Blundell, T.L. | | 登録日 | 1994-07-27 | | 公開日 | 1994-12-20 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
|
|
6VQL
 | |
2MTP
 | |
3C27
 | | Cyanofluorophenylacetamides as Orally Efficacious Thrombin Inhibitors | | 分子名称: | Hirudin-3A, N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide, Thrombin heavy chain, ... | | 著者 | Spurlino, J.C, McMillan, M, Lewandowski, F, Milligan, C. | | 登録日 | 2008-01-24 | | 公開日 | 2009-02-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.182 Å) | | 主引用文献 | Cyanofluorophenylacetamides as Orally Efficacious Thrombin Inhibitors
To be Published
|
|
6LXY
 | | IRAK4 in complex with inhibitor | | 分子名称: | Interleukin-1 receptor-associated kinase 4, N-[(2R)-2-fluoranyl-3-methyl-3-oxidanyl-butyl]-6-[(6-fluoranylpyrazolo[1,5-a]pyrimidin-5-yl)amino]-4-(propan-2-ylamino)pyridine-3-carboxamide, SULFATE ION | | 著者 | Ghosh, K, Bose, S. | | 登録日 | 2020-02-12 | | 公開日 | 2020-11-25 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
Acs Med.Chem.Lett., 11, 2020
|
|
5VZJ
 | |
7SFT
 | | Filamin complex-2 | | 分子名称: | Filamin-A, Integrin alpha-IIb light chain, form 2 | | 著者 | Liu, J, Qin, J. | | 登録日 | 2021-10-04 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
|
|
7SC4
 | | filamin complex-1 | | 分子名称: | Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION | | 著者 | Liu, J, Qin, J. | | 登録日 | 2021-09-27 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
|
|
4DQ9
 | | Crystal structure of the minor pseudopilin EPSH from the type II secretion system of Vibrio cholerae | | 分子名称: | CHLORIDE ION, General secretion pathway protein H, SODIUM ION | | 著者 | Raghunathan, K, Vago, F.S, Grindem, D, Ball, T, Wedemeyer, W.J, Arvidson, D.N. | | 登録日 | 2012-02-15 | | 公開日 | 2013-03-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | The 1.59 angstrom resolution structure of the minor pseudopilin EpsH of Vibrio cholerae reveals a long flexible loop.
Biochim.Biophys.Acta, 1844, 2013
|
|
6KFB
 | | Hydroxynitrile lyase from the millipede, Chamberlinius hualienensis bound with thiocyanate | | 分子名称: | Hydroxynitrile lyase, THIOCYANATE ION, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Motojima, F, Izumi, A, Asano, Y. | | 登録日 | 2019-07-07 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | R-hydroxynitrile lyase from the cyanogenic millipede, Chamberlinius hualienensis-A new entry to the carrier protein family Lipocalines.
Febs J., 288, 2021
|
|
4V33
 | | Crystal structure of the putative polysaccharide deacetylase BA0330 from bacillus anthracis | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, POLYSACCHARIDE DEACETYLASE-LIKE PROTEIN, ... | | 著者 | Giastas, P, Andreou, A, Bouriotis, V, Eliopoulos, E. | | 登録日 | 2014-10-16 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Two Putative Polysaccharide Deacetylases are Required for Osmotic Stability and Cell Shape Maintenance in Bacillus Anthracis.
J.Biol.Chem., 290, 2015
|
|
7Z3E
 | | XFEL structure of Class Ib ribonucleotide reductase dimanganese(II) NrdF in complex with hydroquinone NrdI from Bacillus cereus | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, MANGANESE (II) ION, Protein NrdI, ... | | 著者 | John, J, Lebrette, H, Aurelius, O, Hogbom, M. | | 登録日 | 2022-03-02 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography.
Elife, 11, 2022
|
|
7Z3D
 | | XFEL structure of Class Ib ribonucleotide reductase dimanganese(II) NrdF in complex with oxidized NrdI from Bacillus cereus | | 分子名称: | FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein NrdI, ... | | 著者 | John, J, Lebrette, H, Aurelius, O, Hogbom, M. | | 登録日 | 2022-03-02 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography.
Elife, 11, 2022
|
|
1EMT
 | | FAB ANTIBODY FRAGMENT OF AN C60 ANTIFULLERENE ANTIBODY | | 分子名称: | IGG ANTIBODY (HEAVY CHAIN), IGG ANTIBODY (LIGHT CHAIN) | | 著者 | Braden, B.C, Goldbaum, F.A, Chen, B.-X, Erlanger, B.F, Kirschner, A.N, Wilson, S.R. | | 登録日 | 2000-03-17 | | 公開日 | 2000-11-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | X-ray crystal structure of an anti-Buckminsterfullerene antibody fab fragment: biomolecular recognition of C(60).
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
7QUR
 | | SARS-CoV-2 Spike with ethylbenzamide-tri-iodo Siallyllactose, C3 symmetry | | 分子名称: | 2,3,5-tris(iodanyl)benzamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | | 登録日 | 2022-01-18 | | 公開日 | 2022-06-01 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
|
|
7QUS
 | | SARS-CoV-2 Spike, C3 symmetry | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | | 登録日 | 2022-01-18 | | 公開日 | 2022-06-08 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
|
|
2K9U
 | |
7M78
 | | Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | 著者 | Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J. | | 登録日 | 2021-03-26 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I.
Sci Rep, 11, 2021
|
|
7M75
 | | Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | 著者 | Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J. | | 登録日 | 2021-03-26 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I.
Sci Rep, 11, 2021
|
|
7M76
 | | Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | 著者 | Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J. | | 登録日 | 2021-03-26 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I.
Sci Rep, 11, 2021
|
|
8R7O
 | |
8RD1
 | | HUWE1 WWE domain in complex with compound 4 | | 分子名称: | 2-(2-hydroxy-2-oxoethyl)-1,3-bis(oxidanylidene)isoindole-5-carboxylic acid, CHLORIDE ION, E3 ubiquitin-protein ligase HUWE1 | | 著者 | Muenzker, L, Zak, K.M, Boettcher, J. | | 登録日 | 2023-12-07 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | | 主引用文献 | A ligand discovery toolbox for the WWE domain family of human E3 ligases.
Commun Biol, 7, 2024
|
|
8RD7
 | | HUWE1 WWE domain in complex with ADP-ribose | | 分子名称: | ACETATE ION, CHLORIDE ION, E3 ubiquitin-protein ligase HUWE1, ... | | 著者 | Muenzker, L, Zak, K.M, Boettcher, J. | | 登録日 | 2023-12-07 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | A ligand discovery toolbox for the WWE domain family of human E3 ligases.
Commun Biol, 7, 2024
|
|
8RD0
 | | HUWE1 WWE domain in complex with compound 3 | | 分子名称: | (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid, CHLORIDE ION, E3 ubiquitin-protein ligase HUWE1 | | 著者 | Muenzker, L, Boettcher, J. | | 登録日 | 2023-12-07 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.765 Å) | | 主引用文献 | A ligand discovery toolbox for the WWE domain family of human E3 ligases.
Commun Biol, 7, 2024
|
|
8R6A
 | |
