1EPR
ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-135,040
Summary for 1EPR
| Entry DOI | 10.2210/pdb1epr/pdb |
| Related | 1EPL 1EPM 1EPN |
| Related PRD ID | PRD_000361 |
| Descriptor | ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide (3 entities in total) |
| Functional Keywords | hydrolase-hydrolase inhibitor complex, acid proteinase, hydrolase/hydrolase inhibitor |
| Biological source | Cryphonectria parasitica (chestnut blight fungus) |
| Total number of polymer chains | 1 |
| Total formula weight | 34598.79 |
| Authors | Badasso, M.,Crawford, M.,Cooper, J.B.,Blundell, T.L. (deposition date: 1994-07-27, release date: 1994-12-20, Last modification date: 2017-11-29) |
| Primary citation | Bailey, D.,Cooper, J.B. A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica. Protein Sci., 3:2129-2143, 1994 Cited by PubMed: 7703859PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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