6VII
 
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6VIH
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6VIJ
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6VIK
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1KQN
 | | Crystal structure of NMN/NaMN adenylyltransferase complexed with NAD | | 分子名称: | NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, XENON | | 著者 | Zhou, T, Kurnasov, O, Tomchick, D.R, Binns, D.D, Grishin, N.V, Marquez, V.E, Osterman, A.L, Zhang, H. | | 登録日 | 2002-01-07 | | 公開日 | 2003-01-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of Human Nicotinamide/Nicotonic Acid Mononucleotide Adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277, 2003
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1KQO
 | | Crystal structure of NMN/NaMN adenylyltransferase complexed with deamido-NAD | | 分子名称: | NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINIC ACID ADENINE DINUCLEOTIDE | | 著者 | Zhou, T, Kurnasov, O, Tomchick, D.R, Binns, D.D, Grishin, N.V, Marquez, V.E, Osterman, A.L, Zhang, H. | | 登録日 | 2002-01-07 | | 公開日 | 2003-01-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase.
Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277, 2002
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1KR2
 | | CRYSTAL STRUCTURE OF HUMAN NMN/NAMN ADENYLYL TRANSFERASE COMPLEXED WITH TIAZOFURIN ADENINE DINUCLEOTIDE (TAD) | | 分子名称: | BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE | | 著者 | Zhou, T, Kurnasov, O, Tomchick, D.R, Binns, D.D, Grishin, N.V, Marquez, V.E, Osterman, A.L, Zhang, H. | | 登録日 | 2002-01-08 | | 公開日 | 2003-01-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase.
Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277, 2002
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1JPZ
 | | Crystal structure of a complex of the heme domain of P450BM-3 with N-Palmitoylglycine | | 分子名称: | BIFUNCTIONAL P-450:NADPH-P450 REDUCTASE, N-PALMITOYLGLYCINE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Haines, D.C, Tomchick, D.R, Machius, M, Peterson, J.A. | | 登録日 | 2001-08-03 | | 公開日 | 2001-11-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Pivotal role of water in the mechanism of P450BM-3.
Biochemistry, 40, 2001
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1U3D
 | | Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana with AMPPNP bound | | 分子名称: | CHLORIDE ION, Cryptochrome 1 apoprotein, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... | | 著者 | Brautigam, C.A, Smith, B.S, Ma, Z, Palnitkar, M, Tomchick, D.R, Machius, M, Deisenhofer, J. | | 登録日 | 2004-07-21 | | 公開日 | 2004-08-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1U3C
 | | Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana | | 分子名称: | CHLORIDE ION, Cryptochrome 1 apoprotein, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... | | 著者 | Brautigam, C.A, Smith, B.S, Ma, Z, Palnitkar, M, Tomchick, D.R, Machius, M, Deisenhofer, J. | | 登録日 | 2004-07-21 | | 公開日 | 2004-08-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Proc.Natl.Acad.Sci.USA, 101, 2004
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4QPM
 | | Structure of Bub1 kinase domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Lin, Z.H, Jia, L.Y, Tomchick, D.R, Luo, X.L, Yu, H.T. | | 登録日 | 2014-06-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2014-12-24 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Substrate-Specific Activation of the Mitotic Kinase Bub1 through Intramolecular Autophosphorylation and Kinetochore Targeting.
Structure, 22, 2014
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4R38
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6MRW
 | | 14-meric ClyA pore complex | | 分子名称: | Hemolysin E, chromosomal | | 著者 | Peng, W, de Souza Santos, M, Li, Y, Tomchick, D.R, Orth, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Plos One, 14, 2019
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6MRT
 | | 12-meric ClyA pore complex | | 分子名称: | Hemolysin E, chromosomal | | 著者 | Peng, W, de Souza Santos, M, Li, Y, Tomchick, D.R, Orth, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Plos One, 14, 2019
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6MRU
 | | 13-meric ClyA pore complex | | 分子名称: | Hemolysin E, chromosomal | | 著者 | Peng, W, de Souza Santos, M, Li, Y, Tomchick, D.R, Orth, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Plos One, 14, 2019
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4PJW
 | | crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog | | 著者 | Hara, K, Chen, Z, Tomchick, D.R, Yu, H. | | 登録日 | 2014-05-12 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
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4PJU
 | | crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) | | 分子名称: | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog | | 著者 | Hara, K, Chen, Z, Tomchick, D.R, Yu, H. | | 登録日 | 2014-05-12 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
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4PK7
 | | crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog | | 著者 | Hara, K, Chen, Z, Tomchick, D.R, Yu, H. | | 登録日 | 2014-05-13 | | 公開日 | 2014-09-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
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1NF3
 | | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 | | 分子名称: | G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ... | | 著者 | Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R. | | 登録日 | 2002-12-12 | | 公開日 | 2003-03-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Embo J., 22, 2003
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1OLS
 | | Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase | | 分子名称: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, GLYCEROL, ... | | 著者 | Wynn, R.M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T. | | 登録日 | 2003-08-12 | | 公開日 | 2003-08-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site.
J.Biol.Chem., 278, 2003
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2CMN
 | | A Proximal Arginine Residue in the Switching Mechanism of the FixL Oxygen Sensor | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, SENSOR PROTEIN FIXL | | 著者 | Gilles-Gonzalez, M.-A, Caceres, A.I, Silva Sousa, E.H, Tomchick, D.R, Brautigam, C.A, Gonzalez, C, Machius, M. | | 登録日 | 2006-05-11 | | 公開日 | 2007-05-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A Proximal Arginine R206 Participates in Switching of the Bradyrhizobium Japonicum Fixl Oxygen Sensor
J.Mol.Biol., 360, 2006
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2BWQ
 | | Crystal Structure of the RIM2 C2A-domain at 1.4 angstrom Resolution | | 分子名称: | REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, SULFATE ION | | 著者 | Dai, H, Tomchick, D.R, Garcia, J, Sudhof, T.C, Machius, M, Rizo, J. | | 登録日 | 2005-07-15 | | 公開日 | 2005-10-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Crystal Structure of the Rim2 C(2)A-Domain at 1.4 A Resolution.
Biochemistry, 44, 2005
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2BNX
 | | Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1 | | 分子名称: | CHLORIDE ION, DIAPHANOUS PROTEIN HOMOLOG 1 | | 著者 | Otomo, T, Otomo, C, Tomchick, D.R, Machius, M, Rosen, M.K. | | 登録日 | 2005-04-05 | | 公開日 | 2005-06-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1
Mol.Cell, 18, 2005
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2CJT
 | | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, UNC-13 HOMOLOG A | | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | | 登録日 | 2006-04-06 | | 公開日 | 2006-06-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch
Plos Biol., 4, 2006
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2CJS
 | | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, ... | | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | | 登録日 | 2006-04-06 | | 公開日 | 2006-06-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch.
Plos Biol., 4, 2006
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