6TQ3
 
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5YOQ
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5XZG
 | | Mouse cGAS bound to the inhibitor RU521 | | 分子名称: | 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*G)-3'), ... | | 著者 | Vincent, J, Adura, C, Gao, P, Luz, A, Lama, L, Asano, Y, Okamoto, R, Imaeda, T, Aida, J, Rothamel, K, Gogakos, T, Steinberg, J, Reasoner, S, Aso, K, Tuschl, T, Patel, D.J, Glickman, J.F, Ascano, M. | | 登録日 | 2017-07-12 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.828 Å) | | 主引用文献 | Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice.
Nat Commun, 8, 2017
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5YRS
 | | X-ray Snapshot of HIV-1 Protease in Action: Observation of Tetrahedral Intermediate and Its SIHB with Catalytic Aspartate | | 分子名称: | PROTEASE, RT-RH oligopeprtide | | 著者 | Das, A, Mahale, S, Prashar, V, Bihani, S, Ferrer, J.-L, Hosur, M.V. | | 登録日 | 2017-11-10 | | 公開日 | 2018-03-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | X-ray snapshot of HIV-1 protease in action: observation of tetrahedral intermediate and short ionic hydrogen bond SIHB with catalytic aspartate.
J. Am. Chem. Soc., 132, 2010
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5Y05
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8JCR
 | | Crystal structure of Procerain from Calotropis gigantea (pH 6.0) | | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, ... | | 著者 | Kumar, A, Jamdar, S.N, Srivastava, G, Makde, R.D. | | 登録日 | 2023-05-11 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of Procerain from Calotropis gigantea
To Be Published
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8JCQ
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8JCS
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4Y3T
 | | Endothiapepsin in complex with fragment 207 | | 分子名称: | (3R)-piperidin-3-yl(piperidin-1-yl)methanone, (3S)-piperidin-3-yl(piperidin-1-yl)methanone, ACETATE ION, ... | | 著者 | Ehrmann, F.R, Huschmann, F.U, Heine, A, Klebe, G. | | 登録日 | 2015-02-10 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Crystallographic Fragment Sreening of an Entire Library
To Be Published
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5Y85
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4Y5A
 | | Endothiapepsin in complex with fragment 206 | | 分子名称: | 1,2-ETHANEDIOL, 1-[5-(trifluoromethyl)furan-2-yl]methanamine, ACETATE ION, ... | | 著者 | Ehrmann, F.R, Huschmann, F.U, Heine, A, Klebe, G. | | 登録日 | 2015-02-11 | | 公開日 | 2016-03-02 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystallographic Fragment Sreening of an Entire Library
To Be Published
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4CWP
 | | Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor | | 分子名称: | 5-(1,3-benzodioxol-5-ylmethyl)[1,2,4]triazolo[1,5-c]quinazolin-2-amine, HEAT SHOCK PROTEIN HSP 90-ALPHA | | 著者 | Casale, E, Amboldi, N, Brasca, G, Caronni, D, Colombo, N, Dalvit, C, Felder, E.R, Fogliatto, G, Isacchi, A, Mantegani, S, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Casuscelli, F. | | 登録日 | 2014-04-03 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Fragment-Based Hit Discovery and Structure-Based Optimization of Aminotriazoloquinazolines as Novel Hsp90 Inhibitors.
Bioorg.Med.Chem., 22, 2014
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4Y3R
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1RY7
 | | Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1 | | 分子名称: | Fibroblast growth factor receptor 3, Heparin-binding growth factor 1 | | 著者 | Olsen, S.K, Ibrahimi, O.A, Raucci, A, Zhang, F, Eliseenkova, A.V, Yayon, A, Basilico, C, Linhardt, R.J, Schlessinger, J, Mohammadi, M. | | 登録日 | 2003-12-19 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.
Proc.Natl.Acad.Sci.Usa, 101, 2004
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5YA8
 | | Crystal structure of scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity complexed with myo-inositol | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | | 著者 | Fukano, K, Shimizu, T, Sasaki, Y, Nakamura, A, Yajima, S. | | 登録日 | 2017-08-31 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification
PLoS ONE, 13, 2018
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8JQU
 | | Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Pandey, D, Zohib, M, Pal, R.K, Biswal, B.K, Arora, A. | | 登録日 | 2023-06-14 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani
To Be Published
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8JMM
 | | Structure of XBB spike protein (S) dimer-trimer in complex with bispecific antibody G7-Fc at 3.75 Angstroms resolution. | | 分子名称: | 7F3 Fv, GW01 Fv, Spike glycoprotein | | 著者 | Hao, A, Mao, Q, Chen, Z, Huang, J, Sun, L. | | 登録日 | 2023-06-05 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Structure of XBB spike protein (S) dimer-trimer in complex with bispecific antibody G7-Fc at 3.75 Angstroms resolution.
To Be Published
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8JPV
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2JA9
 | | Structure of the N-terminal deletion of yeast exosome component Rrp40 | | 分子名称: | EXOSOME COMPLEX EXONUCLEASE RRP40 | | 著者 | Oddone, A, Lorentzen, E, Basquin, J, Gasch, A, Rybin, V, Conti, E, Sattler, M. | | 登録日 | 2006-11-24 | | 公開日 | 2006-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and Biochemical Characterization of the Yeast Exosome Component Rrp40
Embo Rep., 8, 2007
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8J91
 | | Cryo-EM structure of nucleosome containing Arabidopsis thaliana histones | | 分子名称: | DNA (169-MER), HTA13, Histone H2B.6, ... | | 著者 | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | | 登録日 | 2023-05-02 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1
Nat Commun, 2024
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6TQF
 | | The structure of ABC transporter Rv1819c in AMP-PNP bound state | | 分子名称: | ABC transporter ATP-binding protein/permease, DODECYL-BETA-D-MALTOSIDE, MAGNESIUM ION, ... | | 著者 | Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
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8J90
 | | Cryo-EM structure of DDM1-nucleosome complex | | 分子名称: | ATP-dependent DNA helicase DDM1, DNA (169-MER), HTA6, ... | | 著者 | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | | 登録日 | 2023-05-02 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.71 Å) | | 主引用文献 | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1
Nat Commun, 2024
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8J92
 | | Cryo-EM structure of nucleosome containing Arabidopsis thaliana H2A.W | | 分子名称: | DNA (169-MER), HTA6, HTB9, ... | | 著者 | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | | 登録日 | 2023-05-02 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1
Nat Commun, 2024
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1S6Y
 | | 2.3A crystal structure of phospho-beta-glucosidase | | 分子名称: | 6-phospho-beta-glucosidase | | 著者 | Tereshko, V, Dementieva, I, Kim, Y, Collat, F, Joachimiak, A, Kossiakoff, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-01-28 | | 公開日 | 2004-05-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | 2.3A CRYSTAL STRUCTURE OF PHOSPHO-BETA-GLUCOSIDASE, licH Gene Product from BACILLUS STEAROTHERMOPHILUS
To be Published
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4Y3S
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