1RY7

Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1

Summary for 1RY7

Entry DOI	10.2210/pdb1ry7/pdb
Related	1DJS 1EVT 1NUN
Descriptor	Heparin-binding growth factor 1, Fibroblast growth factor receptor 3 (2 entities in total)
Functional Keywords	fgf-fgfr complex; beta trefoil; ig domain, growth factor-growth factor receptor complex, growth factor/growth factor receptor
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P05230 Membrane; Single-pass type I membrane protein: P22607
Total number of polymer chains	2
Total formula weight	53777.13
Authors	Olsen, S.K.,Ibrahimi, O.A.,Raucci, A.,Zhang, F.,Eliseenkova, A.V.,Yayon, A.,Basilico, C.,Linhardt, R.J.,Schlessinger, J.,Mohammadi, M. (deposition date: 2003-12-19, release date: 2004-02-10, Last modification date: 2023-08-23)
Primary citation	Olsen, S.K.,Ibrahimi, O.A.,Raucci, A.,Zhang, F.,Eliseenkova, A.V.,Yayon, A.,Basilico, C.,Linhardt, R.J.,Schlessinger, J.,Mohammadi, M. Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity. Proc.Natl.Acad.Sci.Usa, 101:935-940, 2004 Cited by PubMed: 14732692 DOI: 10.1073/pnas.0307287101 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation