4HWY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hwy by Molmil](/molmil-images/mine/4hwy) | Trypanosoma brucei procathepsin B solved from 40 fs free-electron laser pulse data by serial femtosecond X-ray crystallography | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cysteine peptidase C (CPC), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Redecke, L, Nass, K, DePonte, D.P, White, T.A, Rehders, D, Barty, A, Stellato, F, Liang, M, Barends, T.R.M, Boutet, S, Williams, G.W, Messerschmidt, M, Seibert, M.M, Aquila, A, Arnlund, D, Bajt, S, Barth, T, Bogan, M.J, Caleman, C, Chao, T.-C, Doak, R.B, Fleckenstein, H, Frank, M, Fromme, R, Galli, L, Grotjohann, I, Hunter, M.S, Johansson, L.C, Kassemeyer, S, Katona, G, Kirian, R.A, Koopmann, R, Kupitz, C, Lomb, L, Martin, A.V, Mogk, S, Neutze, R, Shoemann, R.L, Steinbrener, J, Timneanu, N, Wang, D, Weierstall, U, Zatsepin, N.A, Spence, J.C.H, Fromme, P, Schlichting, I, Duszenko, M, Betzel, C, Chapman, H. | 登録日 | 2012-11-09 | 公開日 | 2012-12-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser. Science, 339, 2013
|
|
7YWJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ywj by Molmil](/molmil-images/mine/7ywj) | Crystal structure of an engineered TycA variant, TycA pPLA (L313P) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ... | 著者 | Mittl, P, Camus, A, Truong, G, Markert, G, Hilvert, D. | 登録日 | 2022-02-14 | 公開日 | 2022-09-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | 主引用文献 | Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids. J.Am.Chem.Soc., 144, 2022
|
|
1DPJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dpj by Molmil](/molmil-images/mine/1dpj) | THE STRUCTURE OF PROTEINASE A COMPLEXED WITH IA3 PEPTIDE INHIBITOR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEINASE A, PROTEINASE INHIBITOR IA3 PEPTIDE, ... | 著者 | Li, M, Phylip, H.L, Lees, W.E, Winther, J.R, Dunn, B.M, Wlodawer, A, Kay, J, Guschina, A. | 登録日 | 1999-12-27 | 公開日 | 2000-05-03 | 最終更新日 | 2021-07-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol., 7, 2000
|
|
4P3Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p3z by Molmil](/molmil-images/mine/4p3z) | Chlamydia pneumoniae CopN (D29 construct) | 分子名称: | CopN, GLYCEROL, SULFATE ION | 著者 | Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B. | 登録日 | 2014-03-10 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae. J.Biol.Chem., 289, 2014
|
|
2A6Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2a6z by Molmil](/molmil-images/mine/2a6z) | Crystal structure of Emp47p carbohydrate recognition domain (CRD), monoclinic crystal form 1 | 分子名称: | Emp47p (form2) | 著者 | Satoh, T, Sato, K, Kanoh, A, Yamashita, K, Kato, R, Nakano, A, Wakatsuki, S. | 登録日 | 2005-07-04 | 公開日 | 2006-01-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p. J.Biol.Chem., 281, 2006
|
|
1MK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mk4 by Molmil](/molmil-images/mine/1mk4) | Structure of Protein of Unknown Function YqjY from Bacillus subtilis, Probable Acetyltransferase | 分子名称: | Hypothetical protein yqjY | 著者 | Zhang, R, Dementiva, I, Mo, A, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-08-28 | 公開日 | 2003-04-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 1.7A crystal structure of a hypothetical protein yqjY
from Bacillus subtilis To be Published
|
|
2A6V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2a6v by Molmil](/molmil-images/mine/2a6v) | Crystal structure of Emp46p carbohydrate recognition domain (CRD), potassium-bound form | 分子名称: | 1,2-ETHANEDIOL, Emp46p, POTASSIUM ION | 著者 | Satoh, T, Sato, K, Kanoh, A, Yamashita, K, Kato, R, Nakano, A, Wakatsuki, S. | 登録日 | 2005-07-04 | 公開日 | 2006-01-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p. J.Biol.Chem., 281, 2006
|
|
3GJK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gjk by Molmil](/molmil-images/mine/3gjk) | crystal structure of a DNA duplex containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one | 分子名称: | 5'-D(*CP*GP*CP*GP*AP*A)-3', 5'-D(P*TP*TP*(B7C)P*GP*CP*G)-3', POTASSIUM ION | 著者 | Takenaka, A, Juan, E.C.M, Shimizu, S, Haraguchi, T, Xiao, M, Kurose, T, Ohkubo, A, Sekine, M, Shibata, T, Millington, C.L, Williams, D.M. | 登録日 | 2009-03-09 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into the stabilizing contributions of bicyclic cytosine analogues: crystal structures of DNA duplexes containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one To be Published
|
|
1LVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lvb by Molmil](/molmil-images/mine/1lvb) | CATALYTICALLY INACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH SUBSTRATE | 分子名称: | CATALYTIC DOMAIN OF THE NUCLEAR INCLUSION PROTEIN A (NIA), GLYCEROL, OLIGOPEPTIDE SUBSTRATE FOR THE PROTEASE | 著者 | Phan, J, Zdanov, A, Evdokimov, A.G, Tropea, J.E, Peters III, H.K, Kapust, R.B, Li, M, Wlodawer, A, Waugh, D.S. | 登録日 | 2002-05-28 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the substrate specificity of tobacco etch virus protease. J.Biol.Chem., 277, 2002
|
|
3GQY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gqy by Molmil](/molmil-images/mine/3gqy) | Activator-Bound Structure of Human Pyruvate Kinase M2 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-TARTARIC ACID, ... | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-03-24 | 公開日 | 2009-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2 to be published
|
|
7Z05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z05 by Molmil](/molmil-images/mine/7z05) | White Bream virus N7-Methyltransferase | 分子名称: | DI(HYDROXYETHYL)ETHER, Non-structural protein 1, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Shannon, A, Gauffre, P, Canard, B, Ferron, F. | 登録日 | 2022-02-22 | 公開日 | 2022-09-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome. Nucleic Acids Res., 50, 2022
|
|
3CQY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cqy by Molmil](/molmil-images/mine/3cqy) | Crystal structure of a functionally unknown protein (SO_1313) from Shewanella oneidensis MR-1 | 分子名称: | Anhydro-N-acetylmuramic acid kinase, CHLORIDE ION, SUCCINIC ACID | 著者 | Tan, K, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-04-03 | 公開日 | 2008-04-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structure of a functionally unknown protein (SO_1313) from Shewanella oneidensis MR-1. To be Published
|
|
3GSN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gsn by Molmil](/molmil-images/mine/3gsn) | Crystal structure of the public RA14 TCR in complex with the HCMV dominant NLV/HLA-A2 epitope | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, HCMV pp65 fragment 495-503 (NLVPMVATV), ... | 著者 | Gras, S, Saulquin, X, Reiser, J.-B, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | 登録日 | 2009-03-27 | 公開日 | 2009-08-04 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
|
|
4NI1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ni1 by Molmil](/molmil-images/mine/4ni1) | Quaternary R CO-liganded hemoglobin structure in complex with a thiol containing compound | 分子名称: | 5-[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | 著者 | Safo, M.K, Meadows, J, Ko, T.-P, Nakagawa, A, Zapol, W. | 登録日 | 2013-11-05 | 公開日 | 2014-09-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling. Acs Chem.Biol., 9, 2014
|
|
2YNX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ynx by Molmil](/molmil-images/mine/2ynx) | Crystal Structure of Ancestral Thioredoxin Relative to Last Archaea Common Ancestor (LACA) from the Precambrian Period | 分子名称: | ACETATE ION, LACA THIOREDOXIN, SODIUM ION | 著者 | Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. | 登録日 | 2012-10-19 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | 主引用文献 | Conservation of Protein Structure Over Four Billion Years Structure, 21, 2013
|
|
3CUO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cuo by Molmil](/molmil-images/mine/3cuo) | Crystal structure of the predicted DNA-binding transcriptional regulator from E. coli | 分子名称: | Uncharacterized HTH-type transcriptional regulator ygaV | 著者 | Zhang, R, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-04-16 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of the predicted DNA-binding transcriptional regulator from E. coli. To be Published
|
|
3GSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gsu by Molmil](/molmil-images/mine/3gsu) | Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5T peptide variant | 分子名称: | Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5T (NLVPTVATV), ... | 著者 | Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | 登録日 | 2009-03-27 | 公開日 | 2009-08-04 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
|
|
1Z8A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z8a by Molmil](/molmil-images/mine/1z8a) | Human Aldose Reductase complexed with novel Sulfonyl-pyridazinone Inhibitor | 分子名称: | 6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | 著者 | Steuber, H, Zentgraf, M, Podjarny, A, Heine, A, Klebe, G. | 登録日 | 2005-03-30 | 公開日 | 2006-03-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | High-resolution crystal structure of aldose reductase complexed with the novel sulfonyl-pyridazinone inhibitor exhibiting an alternative active site anchoring group. J.Mol.Biol., 356, 2006
|
|
4NE3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ne3 by Molmil](/molmil-images/mine/4ne3) | Human MHF1-MHF2 complex | 分子名称: | Centromere protein S, Centromere protein X | 著者 | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | 登録日 | 2013-10-28 | 公開日 | 2013-12-25 | 最終更新日 | 2014-02-12 | 実験手法 | X-RAY DIFFRACTION (1.8007 Å) | 主引用文献 | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun, 5, 2014
|
|
1Z89
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z89 by Molmil](/molmil-images/mine/1z89) | Human Aldose Reductase complexed with novel Sulfonyl-pyridazinone Inhibitor | 分子名称: | 6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | 著者 | Steuber, H, Zentgraf, M, Podjarny, A, Heine, A, Klebe, G. | 登録日 | 2005-03-30 | 公開日 | 2006-03-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | High-resolution crystal structure of aldose reductase complexed with the novel sulfonyl-pyridazinone inhibitor exhibiting an alternative active site anchoring group. J.Mol.Biol., 356, 2006
|
|
3D2J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d2j by Molmil](/molmil-images/mine/3d2j) | Structure of berberine bridge enzyme from Eschscholzia californica, tetragonal crystal form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | 著者 | Winkler, A, Lyskowski, A, Macheroux, P, Gruber, K. | 登録日 | 2008-05-08 | 公開日 | 2008-10-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | A concerted mechanism for berberine bridge enzyme Nat.Chem.Biol., 4, 2008
|
|
4NRA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nra by Molmil](/molmil-images/mine/4nra) | Crystal Structure of the bromodomain of human BAZ2B in complex with compound-6 E11322 | 分子名称: | 1,2-ETHANEDIOL, 1-(8-chloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)ethanone, Bromodomain adjacent to zinc finger domain protein 2B | 著者 | Chaikuad, A, Felletar, I, Ferguson, F.M, Filippakopoulos, P, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-11-26 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain. J.Med.Chem., 56, 2013
|
|
7YX8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yx8 by Molmil](/molmil-images/mine/7yx8) | Crystal structure of the AM0627 (E326A) inactive mutant in complex with PSGL-1-like bis-T glycopeptide and Zn2+ | 分子名称: | GLYCEROL, PSGL-1-like bis-T glycopeptide, Peptidase M60 domain-containing protein, ... | 著者 | Taleb, V, Liao, Q, Narimatsu, Y, Garcia-Garcia, A, Companon, I, Borges, R.J, Gonzalez-Ramirez, A.M, Corzana, F, Clausen, H, Rovira, C, Hurtado-Guerrero, R. | 登録日 | 2022-02-15 | 公開日 | 2022-07-20 | 最終更新日 | 2022-08-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut. Nat Commun, 13, 2022
|
|
1ZCR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zcr by Molmil](/molmil-images/mine/1zcr) | Crystal structure of human Transthyretin with bound iodide | 分子名称: | IODIDE ION, Transthyretin | 著者 | Hornberg, A, Hultdin, U.W, Olofsson, A, Sauer-Eriksson, A.E. | 登録日 | 2005-04-13 | 公開日 | 2005-07-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The effect of iodide and chloride on transthyretin structure and stability Biochemistry, 44, 2005
|
|
7Z5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z5a by Molmil](/molmil-images/mine/7z5a) | |