7LUR
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8F4O
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![BU of 8f4o by Molmil](/molmil-images/mine/8f4o) | Apo structure of the TPP riboswitch aptamer domain | 分子名称: | IRIDIUM HEXAMMINE ION, TETRAETHYLENE GLYCOL, TPP riboswitch aptamer domain, ... | 著者 | Lee, H.-K, Wang, Y.-X, Stagno, J.R. | 登録日 | 2022-11-11 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state. Structure, 31, 2023
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7WOI
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![BU of 7woi by Molmil](/molmil-images/mine/7woi) | Structure of the shaft pilin Spa2 from Corynebacterium glutamicum | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Spa2 | 著者 | Wu, Y.F, Wang, L.T, Huang, Y.Y, Zhong, C, Zhou, J. | 登録日 | 2022-01-21 | 公開日 | 2023-01-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Accelerating the design of pili-enabled living materials using an integrative technological workflow. Nat.Chem.Biol., 2023
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7WQV
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![BU of 7wqv by Molmil](/molmil-images/mine/7wqv) | Crystal structure of a neutralizing monoclonal antibody (Ab08) in complex with SARS-CoV-2 receptor-binding domain (RBD) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab08, ... | 著者 | Zha, J, Meng, L, Zhang, X, Li, D. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy. Plos Pathog., 19, 2023
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7CWN
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![BU of 7cwn by Molmil](/molmil-images/mine/7cwn) | P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Wang, N, Wang, X. | 登録日 | 2020-08-29 | 公開日 | 2020-12-16 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection. Cell Res., 31, 2021
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5SWD
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![BU of 5swd by Molmil](/molmil-images/mine/5swd) | Structure of the adenine riboswitch aptamer domain in an intermediate-bound state | 分子名称: | ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ... | 著者 | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | 登録日 | 2016-08-08 | 公開日 | 2016-11-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541, 2017
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5SWE
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![BU of 5swe by Molmil](/molmil-images/mine/5swe) | Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography | 分子名称: | ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain | 著者 | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | 登録日 | 2016-08-08 | 公開日 | 2016-11-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541, 2017
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2MBK
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![BU of 2mbk by Molmil](/molmil-images/mine/2mbk) | The Clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed | 分子名称: | Crossveinless 2 | 著者 | Mueller, T.D, Fiebig, J.E, Weidauer, S.E, Qiu, L, Bauer, M, Schmieder, P, Beerbaum, M, Zhang, J, Oschkinat, H, Sebald, W. | 登録日 | 2013-08-02 | 公開日 | 2013-10-16 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed. Molecules, 18, 2013
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7X8X
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![BU of 7x8x by Molmil](/molmil-images/mine/7x8x) | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease | 分子名称: | 4-[1-[3-[4-[(4-fluoranyl-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-quinazolin-7-yl]oxypropyl]piperidin-4-yl]benzamide, 4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit 1, ... | 著者 | Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z. | 登録日 | 2022-03-15 | 公開日 | 2023-04-12 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Discovery and Mechanistic Study of Novel Mycobacterium tuberculosis ClpP1P2 Inhibitors J.Med.Chem., 66, 2023
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7X31
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6JNL
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![BU of 6jnl by Molmil](/molmil-images/mine/6jnl) | REF6 ZnF2-4-NAC004 complex | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*TP*GP*TP*TP*TP*TP*G)-3'), ... | 著者 | Yao, Q.Q, Wu, B.X, Ma, J.B. | 登録日 | 2019-03-17 | 公開日 | 2019-03-27 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | DNA methylation repels targeting of Arabidopsis REF6. Nat Commun, 10, 2019
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3SRR
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3SQY
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3SR5
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3SRW
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7C7P
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![BU of 7c7p by Molmil](/molmil-images/mine/7c7p) | Crystal structure of the SARS-CoV-2 main protease in complex with Telaprevir | 分子名称: | (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, 3C-like proteinase, CHLORIDE ION | 著者 | Zeng, R, Qiao, J.X, Wang, Y.F, Li, Y.S, Yao, R, Yang, S.Y, Lei, J. | 登録日 | 2020-05-26 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | SARS-CoV-2 M pro inhibitors with antiviral activity in a transgenic mouse model. Science, 371, 2021
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8FQ7
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![BU of 8fq7 by Molmil](/molmil-images/mine/8fq7) | Nanobody with WIW inserted in CDR3 loop to Inhibit Growth of Alzheimer's Tau fibrils | 分子名称: | GLYCEROL, Nanobody with WIW insert in CDR3 loop to target tau fibrils | 著者 | Abskharon, R, Sawaya, M.R, Cascio, D.C, Eisenberg, D.S. | 登録日 | 2023-01-05 | 公開日 | 2023-10-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAR
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![BU of 8jar by Molmil](/molmil-images/mine/8jar) | Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAL
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![BU of 8jal by Molmil](/molmil-images/mine/8jal) | Structure of CRL2APPBP2 bound with RxxGP degron (dimer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-06 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAQ
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![BU of 8jaq by Molmil](/molmil-images/mine/8jaq) | Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-06 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAU
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![BU of 8jau by Molmil](/molmil-images/mine/8jau) | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAS
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![BU of 8jas by Molmil](/molmil-images/mine/8jas) | Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAV
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![BU of 8jav by Molmil](/molmil-images/mine/8jav) | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8GVK
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7XGR
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