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4IQB
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BU of 4iqb by Molmil
High Resolution Crystal Structure of C.elegans Thymidylate Synthase
分子名称: SULFATE ION, Thymidylate synthase
著者Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W.
登録日2013-01-11
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.
J. Mol. Graph. Model., 77, 2017
6MTE
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BU of 6mte by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state)
分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
著者Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
登録日2018-10-19
公開日2018-11-21
最終更新日2019-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
5NL9
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BU of 5nl9 by Molmil
Crystal structure of a peroxide stress regulator from Leptospira interrogans
分子名称: POTASSIUM ION, Transcriptional regulator (FUR family), UNKNOWN ATOM OR ION, ...
著者Saul, F.A, Haouz, A, Picardeau, M, Benaroudj, N.
登録日2017-04-04
公開日2017-11-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and function of the Leptospira interrogans peroxide stress regulator (PerR), an atypical PerR devoid of a structural metal-binding site.
J. Biol. Chem., 293, 2018
2YGV
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BU of 2ygv by Molmil
Conserved N-terminal domain of the yeast Histone Chaperone Asf1 in complex with the C-terminal fragment of Rad53
分子名称: GLYCEROL, HISTONE CHAPERONE ASF1, SERINE/THREONINE-PROTEIN KINASE RAD53, ...
著者Jiao, Y, Seeger, K, Murciano, B, Ledu, M.H, Charbonnier, J.B, Legrand, P, Lautrette, A, Gaubert, A, Mousson, F, Guerois, R, Mann, C, Ochsenbein, F.
登録日2011-04-21
公開日2012-02-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Surprising Complexity of the Asf1 Histone Chaperone-Rad53 Kinase Interaction
Proc.Natl.Acad.Sci.USA, 109, 2012
6N0V
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BU of 6n0v by Molmil
tRNA ligase
分子名称: MANGANESE (II) ION, tRNA ligase
著者Banerjee, A, Goldgur, Y, Shuman, S.
登録日2018-11-07
公開日2019-01-09
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structure and two-metal mechanism of fungal tRNA ligase.
Nucleic Acids Res., 47, 2019
4J12
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BU of 4j12 by Molmil
monomeric Fc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, human Fc fragment
著者Ishino, T, Wang, M, Mosyak, L, Tam, A, Duan, W, Svenson, K, Joyce, A, O'Hara, D, Lin, L, Somers, W, Kriz, R.
登録日2013-01-31
公開日2013-05-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics.
J.Biol.Chem., 288, 2013
6N1N
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BU of 6n1n by Molmil
Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386
分子名称: Beta-lactamase, GLYCEROL, SULFATE ION
著者Michalska, K, Tesar, C, Endres, M, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-11-09
公開日2018-12-19
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386
To Be Published
5NNL
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Inactive dihydroorotase-like domain of Chaetomium thermophilum CAD-like multifunctional protein
分子名称: Inactive dihydroorotase-like domain
著者Ramon-Maiques, S, Moreno-Morcillo, M, Grande-Garcia, A.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
6N42
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BU of 6n42 by Molmil
Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition
分子名称: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ...
著者Liu, A, Li, J.
登録日2018-11-16
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine.
Biochemistry, 58, 2019
2N59
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BU of 2n59 by Molmil
Solution Structure of R. palustris CsgH
分子名称: Putative uncharacterized protein CsgH
著者Hawthorne, W.J, Taylor, J.D, Escalera-Maurer, A, Lambert, S, Koch, M, Scull, N, Sefer, L, Xu, Y, Matthews, S.J.
登録日2015-07-13
公開日2016-05-11
実験手法SOLUTION NMR
主引用文献Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones.
Sci Rep, 6, 2016
3J2N
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BU of 3j2n by Molmil
The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the contracted T4 tail
分子名称: Tail connector protein Gp15, Tail sheath protein Gp18
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-10
公開日2013-03-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (16 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
5NEK
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BU of 5nek by Molmil
Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with acetazolamide
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ACETATE ION, Peptidoglycan N-acetylglucosamine deacetylase, ...
著者Andreou, A, Giastas, P, Eliopoulos, E.E.
登録日2017-03-10
公開日2018-02-21
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (3.057 Å)
主引用文献Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
1G1B
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BU of 1g1b by Molmil
CHORISMATE LYASE (WILD-TYPE) WITH BOUND PRODUCT
分子名称: CHORISMATE LYASE, P-HYDROXYBENZOIC ACID
著者Gallagher, D.T, Mayhew, M, Holden, M.J, Kim, K.J, Howard, A, Vilker, V.L.
登録日2000-10-11
公開日2001-04-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The crystal structure of chorismate lyase shows a new fold and a tightly retained product.
Proteins, 44, 2001
8DU7
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BU of 8du7 by Molmil
Room-temperature serial synchrotron crystallography (SSX) structure of apo PTP1B
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
著者Ebrahim, A, Sharma, S, Keedy, D.A.
登録日2022-07-27
公開日2022-08-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B.
Acta Crystallogr.,Sect.F, 79, 2023
1JGE
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BU of 1jge by Molmil
HLA-B*2705 bound to nona-peptide m9
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 B*2705 ALPHA CHAIN, ...
著者Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2001-06-25
公開日2002-10-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations
J.Biol.Chem., 277, 2002
6N8C
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BU of 6n8c by Molmil
Structure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR
分子名称: Huntingtin
著者Schwieters, C.D, Kotler, S.A, Schmidt, T, Ceccon, A, Ghirlando, R, Libich, D.S, Clore, G.M.
登録日2018-11-29
公開日2019-02-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
7XQ7
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BU of 7xq7 by Molmil
The complex structure of WT-Mpro
分子名称: 3C-like proteinase nsp5, SODIUM ION
著者Sahoo, P, Lenka, D.R, Kumar, A.
登録日2022-05-06
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
Acs Pharmacol Transl Sci, 6, 2023
5N5M
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BU of 5n5m by Molmil
Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and (R)-3-(2-((isoquinolin-5-ylmethyl)(methyl)carbamoyl)phenyl)pyrrolidin-1-ium
分子名称: Pimtide, Serine/threonine-protein kinase pim-1, ~{N}-(isoquinolin-5-ylmethyl)-~{N}-methyl-2-[(3~{R})-pyrrolidin-3-yl]benzamide
著者Siefker, C, Heine, A, Klebe, G.
登録日2017-02-14
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献A crystallographic fragment study with human Pim-1 kinase
to be published
7WYI
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BU of 7wyi by Molmil
Native Photosystem I of Chlamydomonas reinhardtii
分子名称: CHLOROPHYLL A, CHLOROPHYLL A ISOMER, CHLOROPHYLL B, ...
著者Kurisu, G, Gerle, C, Mitsuoka, K, Kawamoto, A, Tanaka, H.
登録日2022-02-16
公開日2023-02-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Three structures of PSI-LHCI from Chlamydomonas reinhardtii suggest a resting state re-activated by ferredoxin.
Biochim Biophys Acta Bioenerg, 1864, 2023
4JL0
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BU of 4jl0 by Molmil
Crystal structure of PcrH in complex with the chaperone binding region of PopB
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PopB, Regulatory protein PcrH
著者Discola, K.F, Forster, A, Simorre, J.P, Attree, I, Dessen, A, Job, V.
登録日2013-03-12
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa.
J.Biol.Chem., 289, 2014
7WZN
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PSI-LHCI from Chlamydomonas reinhardtii with bound ferredoxin
分子名称: CHLOROPHYLL A, CHLOROPHYLL A ISOMER, CHLOROPHYLL B, ...
著者Kurisu, G, Gerle, C, Mitsuoka, K, Kawamoto, A, Tanaka, H.
登録日2022-02-18
公開日2023-02-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Three structures of PSI-LHCI from Chlamydomonas reinhardtii suggest a resting state re-activated by ferredoxin.
Biochim Biophys Acta Bioenerg, 1864, 2023
3TU8
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Crystal Structure of the Burkholderia Lethal Factor 1 (BLF1)
分子名称: BROMIDE ION, Burkholderia Lethal Factor 1 (BLF1)
著者Cruz, A, Hautbergue, G.M, Artymiuk, P.J, Baker, P.J, Chang, C.T, Mahadi, N.M, Mobbs, G.W, Mohamed, R, Nathan, S, Partridge, L.J, Raih, M.F, Ruzheinikov, S.N, Sedelnikova, S.E, Wilson, S.A, Rice, D.W.
登録日2011-09-16
公開日2011-11-30
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A.
Science, 334, 2011
1XYO
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BU of 1xyo by Molmil
STRUCTURAL COMPARISON OF TWO MAJOR ENDO-1,4-BETA-XYLANASES FROM TRICHODREMA REESEI
分子名称: ENDO-1,4-BETA-XYLANASE II
著者Rouvinen, J, Torronen, A.
登録日1994-08-09
公開日1995-08-08
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural comparison of two major endo-1,4-xylanases from Trichoderma reesei.
Biochemistry, 34, 1995
5N1C
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Iodinated form of the Mycobacterium tuberculosis repressor EthR2
分子名称: IODIDE ION, Probable transcriptional regulatory protein
著者Wintjens, R, Wohlkonig, A.
登録日2017-02-06
公開日2017-04-26
最終更新日2023-03-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.
Science, 355, 2017
3K35
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Crystal Structure of Human SIRT6
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-6, SULFATE ION, ...
著者Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC)
登録日2009-10-01
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011

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