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2O8P
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Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470
分子名称: 14-3-3 domain containing protein
著者Dong, A, Lew, J, Wasney, G, Lin, L, Hassanali, A, Zhao, Y, Vedadi, M, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Walker, J.R, Bochkarev, A, Hui, R, Brokx, S.J, Structural Genomics Consortium (SGC)
登録日2006-12-12
公開日2007-01-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
5CUJ
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BU of 5cuj by Molmil
Crystal structure of Human Defensin-5 Y27A mutant crystal form 2.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2015-07-24
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Human Enteric alpha-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.
Immunity, 2018
5CUI
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BU of 5cui by Molmil
Crystal structure of Human Defensin-5 R28A mutant.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, ...
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2015-07-24
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Human Enteric alpha-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.
Immunity, 2018
2F6I
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BU of 2f6i by Molmil
Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum
分子名称: ATP-dependent CLP protease, putative
著者Mulichak, A, Loppnau, P, Bray, J, Amani, M, Vedadi, M, Wasney, G, Finerty, P, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C, Hui, R, Plotnikova, O, Structural Genomics Consortium (SGC)
登録日2005-11-29
公開日2005-12-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.
J.Mol.Biol., 404, 2010
5CUM
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BU of 5cum by Molmil
Crystal structure of Human Defensin-5 Y27A mutant crystal form 1.
分子名称: CALCIUM ION, CHLORIDE ION, Defensin-5, ...
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2015-07-24
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Human Enteric alpha-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.
Immunity, 2018
2NPM
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BU of 2npm by Molmil
crystal structure of Cryptosporidium parvum 14-3-3 protein in complex with peptide
分子名称: 14-3-3 domain containing protein, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Dong, A, Lew, J, Wasney, G, Ren, H, Lin, L, Hassanali, A, Qiu, W, Zhao, Y, Doyle, D, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC)
登録日2006-10-27
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
2FBN
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BU of 2fbn by Molmil
Plasmodium falciparum putative FK506-binding protein PFL2275c, C-terminal TPR-containing domain
分子名称: 70 kDa peptidylprolyl isomerase, putative
著者Dong, A, Lew, J, Koeieradzki, I, Sundararajan, E, Melone, M, Wasney, G, Zhao, Y, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC)
登録日2005-12-09
公開日2006-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C-terminal pentapeptide.
Protein Sci., 18, 2009
7C8V
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BU of 7c8v by Molmil
Structure of sybody SR4 in complex with the SARS-CoV-2 S Receptor Binding domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ...
著者Li, T, Yao, H, Cai, H, Qin, W, Li, D.
登録日2020-06-03
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection.
Nat Commun, 12, 2021
7C8W
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Structure of sybody MR17 in complex with the SARS-CoV-2 S receptor-binding domain (RBD)
分子名称: GLYCEROL, Spike protein S1, Synthetic nanobody MR17, ...
著者Li, T, Cai, H, Yao, H, Qin, W, Li, D.
登録日2020-06-03
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection.
Nat Commun, 12, 2021
7TY7
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BU of 7ty7 by Molmil
Cryo-EM structure of human Anion Exchanger 1 bound to Bicarbonate
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, ...
著者Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
登録日2022-02-11
公開日2023-08-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
7TY6
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BU of 7ty6 by Molmil
Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatodihydrostilbene-2,2'-Disulfonic Acid (H2DIDS)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ...
著者Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
登録日2022-02-11
公開日2023-08-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
7TY4
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BU of 7ty4 by Molmil
Cryo-EM structure of human Anion Exchanger 1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, ...
著者Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
登録日2022-02-11
公開日2023-08-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
7TYA
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BU of 7tya by Molmil
Cryo-EM structure of human Anion Exchanger 1 modified with Diethyl Pyrocarbonate (DEPC)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, ...
著者Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
登録日2022-02-11
公開日2023-08-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
7TY8
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BU of 7ty8 by Molmil
Cryo-EM structure of human Anion Exchanger 1 bound to Niflumic Acid
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, ...
著者Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
登録日2022-02-11
公開日2023-08-16
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
7CAN
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BU of 7can by Molmil
Structure of sybody MR17-K99Y in complex with the SARS-CoV-2 S Receptor-binding domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ...
著者Li, T, Yao, H, Cai, H, Qin, W, Li, D.
登録日2020-06-09
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection.
Nat Commun, 12, 2021
7VOH
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BU of 7voh by Molmil
The a-glucosidase QsGH13 from Qipengyuania seohaensis
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, alpha-glucosidase QsGH13
著者Huang, J, Zhai, X.Y.
登録日2021-10-13
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.197 Å)
主引用文献Structure and Function Insight of the alpha-Glucosidase QsGH13 From Qipengyuania seohaensis sp. SW-135.
Front Microbiol, 13, 2022
7CCD
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BU of 7ccd by Molmil
Sulfur binding domain of SprMcrA complexed with phosphorothioated DNA
分子名称: DNA (5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*GP*AS*AP*CP*GP*TP*G)-3'), HNHc domain-containing protein
著者Yu, H, Li, J, Liu, G, Zhao, G, Wang, Y, Hu, W, Deng, Z, Gan, J, Zhao, Y, He, X.
登録日2020-06-16
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses.
Nucleic Acids Res., 48, 2020
7WB0
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BU of 7wb0 by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state with flexible H2 domain
分子名称: NTS-DNA, RNA (115-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAZ
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BU of 7waz by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at ts loading state
分子名称: NTS-DNA, RNA (115-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAY
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BU of 7way by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state
分子名称: DNA (27-MER), DNA (33-MER), RNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WB1
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BU of 7wb1 by Molmil
PlmCasX-sgRNAv2-dsDNA ternary complex at nts loading state
分子名称: NTS-DNA, RNA (121-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
4L0W
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BU of 4l0w by Molmil
Plasmodium yoelii Prx1a modified at the N-terminus forms an artifactual octamer
分子名称: ACETATE ION, SULFATE ION, Thioredoxin peroxidase 1
著者Gretes, M.C, Karplus, P.A.
登録日2013-06-01
公開日2016-11-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Observed octameric assembly of a Plasmodium yoelii peroxiredoxin can be explained by the replacement of native "ball-and-socket" interacting residues by an affinity tag.
Protein Sci., 22, 2013
8UTA
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BU of 8uta by Molmil
yjdF riboswitch from R. gauvreauii in complex with proflavine bound to Fab BL3-6 S97N
分子名称: Fab BL3-6 S97N heavy chain, Fab BL3-6 S97N light chain, MAGNESIUM ION, ...
著者Krochmal, D, Lewicka, A, Piccirilli, J.A.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis for promiscuity in ligand recognition by yjdF riboswitch.
Cell Discov, 10, 2024
8UIW
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BU of 8uiw by Molmil
yjdF riboswitch from R. gauvreauii in complex with chelerythrine bound to Fab BL3-6 S97N
分子名称: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Fab BL3-6 S97N heavy chain, Fab BL3-6 S97N light chain, ...
著者Krochmal, D, Lewicka, A, Piccirilli, J.A.
登録日2023-10-10
公開日2024-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural basis for promiscuity in ligand recognition by yjdF riboswitch.
Cell Discov, 10, 2024
7VRL
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BU of 7vrl by Molmil
Solution structure of Rbfox RRM bound to a non-cognate RNA
分子名称: RNA (5'-R(*UP*GP*CP*AP*UP*AP*U)-3'), RNA binding protein fox-1 homolog 1
著者Yang, F, Varani, G.
登録日2021-10-23
公開日2022-10-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity.
Nat Commun, 14, 2023

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