5CUI

Crystal structure of Human Defensin-5 R28A mutant.

Summary for 5CUI

• Entry DOI: 10.2210/pdb5cui/pdb
• Related: 1ZMP 5CUJ 5CUM
• Descriptor: Defensin-5, CHLORIDE ION, 2-(2-METHOXYETHOXY)ETHANOL, ... (6 entities in total)
• Functional Keywords: paneth cells defensin, human alpha-defensin, intestinal defensin, antimicrobial protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 22512.04

Authors

Tolbert, W.D.,Gohain, N.,Pazgier, M. (deposition date: 2015-07-24, release date: 2016-07-27, Last modification date: 2023-09-27)

• Primary citation: Xu, D.,Liao, C.,Zhang, B.,Tolbert, W.D.,He, W.,Dai, Z.,Zhang, W.,Yuan, W.,Pazgier, M.,Liu, J.,Yu, J.,Sansonetti, P.J.,Bevins, C.L.,Shao, Y.,Lu, W.; Human Enteric alpha-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.; Immunity, 2018; PubMed: 29858013; DOI: 10.1016/j.immuni.2018.04.014

Experimental method

X-RAY DIFFRACTION (2.403 Å)