6LYU
| Structure of the BAM complex | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Xiao, L, Huang, Y. | 登録日 | 2020-02-15 | 公開日 | 2021-01-13 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structures of the beta-barrel assembly machine recognizing outer membrane protein substrates. Faseb J., 35, 2021
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8KHU
| Hepatitis B virus core protein Y132A mutant in complex with THPP derivatives 48 | 分子名称: | (6~{S},7~{R})-6,7-dimethyl-3-(2-oxidanylidenepyrrolidin-1-yl)-~{N}-[3,4,5-tris(fluoranyl)phenyl]-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-5-carboxamide, Capsid protein, GLYCEROL, ... | 著者 | Zhou, Z, Xu, Z.H. | 登録日 | 2023-08-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus. J.Med.Chem., 66, 2023
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6LYR
| Structure of the BAM complex | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Xiao, L, Huang, Y. | 登録日 | 2020-02-15 | 公開日 | 2021-01-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | 主引用文献 | Structures of the beta-barrel assembly machine recognizing outer membrane protein substrates. Faseb J., 35, 2021
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6LYS
| Structure of the BAM complex | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Xiao, L, Huang, Y. | 登録日 | 2020-02-15 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structures of the beta-barrel assembly machine recognizing outer membrane protein substrates. Faseb J., 35, 2021
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6LYQ
| Structure of the BAM complex | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Xiao, L, Huang, Y. | 登録日 | 2020-02-15 | 公開日 | 2021-01-06 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Structures of the beta-barrel assembly machine recognizing outer membrane protein substrates. Faseb J., 35, 2021
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8YFD
| Cryo EM structure of human phosphate channel XPR1 at open state | 分子名称: | Solute carrier family 53 member 1 | 著者 | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | 登録日 | 2024-02-24 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YFX
| Cryo EM structure of human phosphate channel XPR1 at inward-facing state | 分子名称: | Solute carrier family 53 member 1 | 著者 | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | 登録日 | 2024-02-25 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YFW
| Cryo EM structure of human phosphate channel XPR1 at intermediate state | 分子名称: | Solute carrier family 53 member 1 | 著者 | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | 登録日 | 2024-02-25 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YFU
| Cryo EM structure of human phosphate channel XPR1 at intermediate state | 分子名称: | Solute carrier family 53 member 1 | 著者 | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | 登録日 | 2024-02-25 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (4.59 Å) | 主引用文献 | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YET
| Cryo EM structure of human phosphate channel XPR1 in complex with IP6 | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Solute carrier family 53 member 1 | 著者 | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | 登録日 | 2024-02-23 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YF4
| Cryo EM structure of human phosphate channel XPR1 at open and inward-facing state | 分子名称: | CHOLESTEROL HEMISUCCINATE, Solute carrier family 53 member 1 | 著者 | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | 登録日 | 2024-02-24 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YEX
| Cryo EM structure of human phosphate channel XPR1 at apo state | 分子名称: | Solute carrier family 53 member 1 | 著者 | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | 登録日 | 2024-02-23 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8HEF
| The Crystal structure of deuterated S-217622 (Ensitrelvir) bound to the main protease (3CLpro/Mpro) of SARS-CoV-2 | 分子名称: | 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, GLYCEROL | 著者 | Yan, M, Zhang, H. | 登録日 | 2022-11-08 | 公開日 | 2023-04-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2. Antiviral Res., 213, 2023
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5ZUG
| Structure of the bacterial acetate channel SatP | 分子名称: | Succinate-acetate/proton symporter SatP, nonyl beta-D-glucopyranoside | 著者 | Sun, P.C, Li, J.L, Xiao, Q.J, Guan, Z.Y, Deng, D. | 登録日 | 2018-05-07 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Crystal structure of the bacterial acetate transporter SatP reveals that it forms a hexameric channel. J. Biol. Chem., 293, 2018
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6A72
| Copper transporter protein | 分子名称: | ATP7B protein, CALCIUM ION, dioxo(di-mu-sulfide)dimolybdenum | 著者 | Chen, W.B. | 登録日 | 2018-07-01 | 公開日 | 2019-04-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein. Nat Commun, 10, 2019
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8HQ6
| KL2 in complex with CRM1-Ran-RanBP1 | 分子名称: | CHLORIDE ION, CRM1 isoform 1, DIMETHYL SULFOXIDE, ... | 著者 | Sun, Q, Jian, L. | 登録日 | 2022-12-13 | 公開日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. J.Med.Chem., 66, 2023
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8HQ3
| KL1 in complex with CRM1-Ran-RanBP1 | 分子名称: | CHLORIDE ION, CRM1 isoform 1, DIMETHYL SULFOXIDE, ... | 著者 | Sun, Q, Jian, L. | 登録日 | 2022-12-13 | 公開日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. J.Med.Chem., 66, 2023
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1P5J
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7DRB
| Crystal structure of plant receptor like protein RXEG1 with xyloglucanase XEG1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell 12A endoglucanase, ... | 著者 | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | 登録日 | 2020-12-27 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
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7DRC
| Cryo-EM structure of plant receptor like protein RXEG1 in complex with xyloglucanase XEG1 and BAK1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Brassinosteroid insensitive 1-associated receptor kinase 1, ... | 著者 | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | 登録日 | 2020-12-27 | 公開日 | 2022-06-22 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
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7E3L
| Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 58G6 heavy chain, 58G6 light chain, ... | 著者 | Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H. | 登録日 | 2021-02-09 | 公開日 | 2021-09-15 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants. Nat Commun, 12, 2021
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7E3K
| Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | 分子名称: | 13G9 heavy chain, 13G9 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H. | 登録日 | 2021-02-09 | 公開日 | 2021-09-15 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants. Nat Commun, 12, 2021
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6JWE
| structure of RET G-quadruplex in complex with colchicine | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | 著者 | Wang, F, Wang, C, Liu, Y, Lan, W.X, Li, Y.M, Wang, R.X, Cao, C. | 登録日 | 2019-04-20 | 公開日 | 2020-02-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR. Chem.Commun.(Camb.), 56, 2020
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6JWD
| structure of RET G-quadruplex in complex with berberine | 分子名称: | BERBERINE, DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3') | 著者 | Wang, F, Wang, C, Liu, Y, Lan, W.X, Li, Y.M, Wang, R.X, Cao, C. | 登録日 | 2019-04-19 | 公開日 | 2020-04-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR. Chem.Commun.(Camb.), 56, 2020
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8HKX
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