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7CMD
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BU of 7cmd by Molmil
Crystal structure of the SARS-CoV-2 PLpro with GRL0617
分子名称: 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, ZINC ION
著者Gao, X, Cui, S.
登録日2020-07-27
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structure of SARS-CoV-2 papain-like protease.
Acta Pharm Sin B, 11, 2021
7CJD
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BU of 7cjd by Molmil
Crystal structure of the SARS-CoV-2 PLpro C111S mutant
分子名称: 1,2-ETHANEDIOL, Non-structural protein 3, ZINC ION
著者Gao, X, Cui, S.
登録日2020-07-10
公開日2020-09-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Crystal structure of SARS-CoV-2 papain-like protease.
Acta Pharm Sin B, 11, 2021
7CTT
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BU of 7ctt by Molmil
Cryo-EM structure of Favipiravir bound to replicating polymerase complex of SARS-CoV-2 in the pre-catalytic state.
分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
著者Peng, Q, Peng, R, Shi, Y.
登録日2020-08-20
公開日2020-09-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir.
Innovation (N Y), 2, 2021
7D68
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BU of 7d68 by Molmil
Cryo-EM structure of the human glucagon-like peptide-2 receptor-Gs protein complex
分子名称: Glucagon-like peptide 2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, W, Chen, L, Zhou, Q, Zhao, L, Zhang, H, Cong, Z, Shen, D, Zhao, F, Zhou, F, Cai, X, Chen, Y, Zhou, Y, Gadgaard, S, van der Velden, W.J, Zhao, S, Jiang, Y, Rosenkilde, M.M, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2020-09-29
公開日2020-12-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Cell Res., 30, 2020
7FJI
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human Pol III elongation complex
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Hou, H, Xu, Y.
登録日2021-08-04
公開日2021-10-27
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
7FJJ
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human Pol III pre-termination complex
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Hou, H, Xu, Y.
登録日2021-08-04
公開日2021-10-27
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
7EWX
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Crystal structure of Ebinur Lake virus cap snatching endonuclease (P78A mutant)
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EWY
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Crystal structure of Ebinur Lake virus cap snatching endonuclease (D79A mutant)
分子名称: Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EWV
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Crystal structure of Ebinur Lake virus cap snatching endonuclease (H34A mutant)
分子名称: MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EX1
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BU of 7ex1 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease (Y109A mutant)
分子名称: CHLORIDE ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EWZ
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BU of 7ewz by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease (D92A mutant)
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EWW
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Crystal structure of Ebinur Lake virus cap snatching endonuclease (N52A mutant)
分子名称: MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EWU
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BU of 7ewu by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease (WT)
分子名称: MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EX0
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Crystal structure of Ebinur Lake virus cap snatching endonuclease (K108A mutant)
分子名称: MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EX6
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Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 11
分子名称: MANGANESE (II) ION, Replicase, methyl (Z)-4-(4-(4-chlorobenzyl)-1-(2-methylbenzyl)piperidin-4-yl)-2-hydroxy-4-oxobut-2-enoate
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX8
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Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 27
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX4
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Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 5
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX9
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BU of 7ex9 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 28
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX2
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Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with L-742,001 (methyl ester form)
分子名称: MANGANESE (II) ION, Replicase, methyl (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(phenylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoate
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX7
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Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 16
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX3
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BU of 7ex3 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 3
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
8JWS
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ePHD domain of PHD Finger Protein 7 (PHF7)
分子名称: 1,2-ETHANEDIOL, PHD finger protein 7, ZINC ION
著者Bang, I, Lee, H.S, Choi, H.-J.
登録日2023-06-29
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for PHF7-mediated ubiquitination of histone H3.
Genes Dev., 37, 2023
8JWU
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PHD Finger Protein 7 (PHF7) fused to UBE2D2 via a (GSGG)3 linker
分子名称: PHD finger protein 7,Ubiquitin-conjugating enzyme E2 D2, ZINC ION
著者Lee, H.S, Bang, I, Choi, H.-J.
登録日2023-06-29
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Molecular basis for PHF7-mediated ubiquitination of histone H3.
Genes Dev., 37, 2023
8JWJ
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PHD Finger Protein 7 (PHF7) in complex with UBE2D2
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHD finger protein 7, ...
著者Lee, H.S, Bang, I, Choi, H.-J.
登録日2023-06-29
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Molecular basis for PHF7-mediated ubiquitination of histone H3.
Genes Dev., 37, 2023
7X9B
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Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Tang, T, Han, S, Zhao, Q, Wu, B.
登録日2022-03-15
公開日2022-05-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022

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