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4XWT
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BU of 4xwt by Molmil
Crystal structure of RNase J complexed with UMP
分子名称: DR2417, GLYCEROL, MANGANESE (II) ION, ...
著者Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y.
登録日2015-01-29
公開日2015-12-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
5YK3
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BU of 5yk3 by Molmil
human Ragulator complex
分子名称: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ...
著者Wu, G, Mu, Z.
登録日2017-10-12
公開日2019-01-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane
Cell Discov, 3, 2017
7E2P
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BU of 7e2p by Molmil
The Crystal Structure of Mycoplasma bovis enolase
分子名称: Enolase
著者Chen, R, Zhang, S, Gan, R, Wang, W, Ran, T, Shao, G, Xiong, Q, Feng, Z.
登録日2021-02-07
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evidence for the Rapid and Divergent Evolution of Mycoplasmas: Structural and Phylogenetic Analysis of Enolases.
Front Mol Biosci, 8, 2022
7E2Q
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BU of 7e2q by Molmil
Crystal structure of Mycoplasma pneumoniae Enolase
分子名称: Enolase, SULFATE ION
著者Chen, R, Zhang, S, Gan, R, Wang, W, Ran, T, Xiong, Q, Shao, G, Feng, Z.
登録日2021-02-07
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Evidence for the Rapid and Divergent Evolution of Mycoplasmas: Structural and Phylogenetic Analysis of Enolases.
Front Mol Biosci, 8, 2022
5YK5
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BU of 5yk5 by Molmil
structure of the human Lamtor4-Lamtor5 complex
分子名称: Ragulator complex protein LAMTOR4, Ragulator complex protein LAMTOR5
著者Wu, G, Mu, Z.
登録日2017-10-12
公開日2018-12-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane
Cell Discov, 3, 2017
8X8Q
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BU of 8x8q by Molmil
Structure of enterovirus protease in complex host factor
分子名称: 2A protein (Fragment), Actin-histidine N-methyltransferase, ZINC ION
著者Gao, X, Cui, S.
登録日2023-11-28
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction.
Nat Commun, 15, 2024
8X77
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BU of 8x77 by Molmil
Enterovirus proteinase with host factor
分子名称: 2A protein, Actin-histidine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Gao, X, Cui, S.
登録日2023-11-23
公開日2024-05-29
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction.
Nat Commun, 15, 2024
8XAI
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BU of 8xai by Molmil
Crystal structure of Protease CPAVM1 in Bacillus subtilis LjM2
分子名称: Lipoprotein
著者Zhang, J, Wang, C.Y.
登録日2023-12-04
公開日2024-06-19
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Anti-influenza activity of CPAVM1 protease secreted by Bacillus subtilis LjM2.
Antiviral Res., 228, 2024
7M98
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BU of 7m98 by Molmil
ATAD2 bromodomain complexed with histone H4K5ac (res 1-10) ligand
分子名称: ATPase family AAA domain-containing protein 2, Histone H4
著者Malone, K.L, Phillips, M, Nix, J.C, Glass, K.C.
登録日2021-03-30
公開日2021-09-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain.
Int J Mol Sci, 22, 2021
5J5S
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BU of 5j5s by Molmil
Src kinase in complex with a sulfonamide inhibitor
分子名称: N-{4-[8-amino-3-(propan-2-yl)imidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl}-N'-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src
著者Lebedev, I, Feldman, H.C, Georghiou, G, Maly, D.J, Seeliger, M.
登録日2016-04-03
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Structural and Functional Analysis of the Allosteric Modulation of IRE1a with ATP-Competitive Kinase Inhibitors
To Be Published
4U3F
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BU of 4u3f by Molmil
Cytochrome bc1 complex from chicken with designed inhibitor bound
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CARDIOLIPIN, ...
著者Huang, L.-S, Zhu, X.-L, Yang, G.F, Berry, E.A.
登録日2014-07-21
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2312 Å)
主引用文献Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization
Sci Rep, 5, 2015
4OCH
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BU of 4och by Molmil
Apo structure of Smr domain of MutS2 from Deinococcus radiodurans
分子名称: Endonuclease MutS2, GLYCEROL
著者Zhang, H, Zhao, Y, Xu, Q, Hua, Y.J.
登録日2014-01-09
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4001 Å)
主引用文献Structural and functional studies of MutS2 from Deinococcus radiodurans.
Dna Repair, 21, 2014
5EA6
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BU of 5ea6 by Molmil
Crystal Structure of Inhibitor BTA-9881 in Complex with Prefusion RSV F Glycoprotein
分子名称: (9~{b}~{R})-9~{b}-(4-chlorophenyl)-1-pyridin-3-ylcarbonyl-2,3-dihydroimidazo[5,6]pyrrolo[1,2-~{a}]pyridin-5-one, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P.
登録日2015-10-15
公開日2015-12-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Molecular mechanism of respiratory syncytial virus fusion inhibitors.
Nat.Chem.Biol., 12, 2016
5EA5
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BU of 5ea5 by Molmil
Crystal Structure of Inhibitor TMC-353121 in Complex with Prefusion RSV F Glycoprotein
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol, D(-)-TARTARIC ACID, ...
著者Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P.
登録日2015-10-15
公開日2015-12-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Molecular mechanism of respiratory syncytial virus fusion inhibitors.
Nat.Chem.Biol., 12, 2016
5W9N
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BU of 5w9n by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, MERS S
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4OD6
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BU of 4od6 by Molmil
Structure of Smr domain of MutS2 from Deinococcus radiodurans, Mn2+ soaked
分子名称: Endonuclease MutS2
著者Zhang, H, Zhao, Y, Xu, Q, Hua, Y.J.
登録日2014-01-10
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Structural and functional studies of MutS2 from Deinococcus radiodurans.
Dna Repair, 21, 2014
6TG5
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BU of 6tg5 by Molmil
Solution structure of MacpD, a acyl carrier protein, from Pseudomonas fluorescens involved in Mupirocin biosynthesis.
分子名称: MacpD
著者Williams, C, Crump, M.P.
登録日2019-11-15
公開日2020-02-19
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis.
Acs Chem.Biol., 15, 2020
5EA7
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BU of 5ea7 by Molmil
Crystal Structure of Inhibitor BMS-433771 in Complex with Prefusion RSV F Glycoprotein
分子名称: 1-cyclopropyl-3-[[1-(4-oxidanylbutyl)benzimidazol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P.
登録日2015-10-15
公開日2015-12-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献Molecular mechanism of respiratory syncytial virus fusion inhibitors.
Nat.Chem.Biol., 12, 2016
5W9K
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BU of 5w9k by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, Spike glycoprotein
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6A6J
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BU of 6a6j by Molmil
Crystal structure of Zebra fish Y-box protein1 (YB-1) Cold-shock domain in complex with 6mer m5C RNA
分子名称: RNA (5'-R(P*CP*AP*UP*(5MC)P*U)-3'), ZINC ION, Zebra fish Y-box protein1 (YB-1)
著者Zhang, M.M, Wu, B.X, Huang, Y, Ma, J.B.
登録日2018-06-28
公開日2019-06-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.255 Å)
主引用文献RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay.
Mol.Cell, 75, 2019
6KE4
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BU of 6ke4 by Molmil
ABloop reengineered Ferritin Nanocage
分子名称: CALCIUM ION, CHLORIDE ION, FE (III) ION, ...
著者Wang, W.M, Wang, H.F.
登録日2019-07-03
公開日2019-10-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献AB loop engineered ferritin nanocages for drug loading under benign experimental conditions.
Chem.Commun.(Camb.), 55, 2019
5EA8
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BU of 5ea8 by Molmil
Crystal Structure of Prefusion RSV F Glycoprotein Fusion Inhibitor Resistance Mutant D489Y
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, D(-)-TARTARIC ACID, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P.
登録日2015-10-15
公開日2015-12-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular mechanism of respiratory syncytial virus fusion inhibitors.
Nat.Chem.Biol., 12, 2016
4E1Z
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BU of 4e1z by Molmil
Structure of mouse Tyk-2 complexed to a 3-aminoindazole inhibitor
分子名称: N-[5-(4-{[(3-chlorophenyl)sulfonyl]amino}phenyl)-1H-indazol-3-yl]furan-2-carboxamide, Non-receptor tyrosine-protein kinase TYK2
著者Argiriadi, M.A, Talanian, R.V, Borhani, D.W.
登録日2012-03-07
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.
Bmc Struct.Biol., 12, 2012
6IR5
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BU of 6ir5 by Molmil
P domain of GII.3-TV24
分子名称: VP1 Capsid protein
著者Yang, Y.
登録日2018-11-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of host ligand specificity change of GII porcine noroviruses from their closely related GII human noroviruses.
Emerg Microbes Infect, 8, 2019
6IK4
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BU of 6ik4 by Molmil
A Novel M23 Metalloprotease Pseudoalterin from Deep-sea
分子名称: Elastinolytic metalloprotease, GLYCEROL, ZINC ION
著者Zhao, H.L, Tang, B.L, Yang, J, Chen, X.L, Zhang, Y.Z.
登録日2018-10-14
公開日2019-10-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria.
Nat Commun, 11, 2020

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