Search by PDB author

Crystal Structure of the VAV2 SH2 domain in complex with APP phosphorylated peptide
分子名称:	Amyloid beta A4 protein-binding family B member 1 (protein), Guanine nucleotide exchange factor VAV2
著者	Zhang, Y.J, Liu, Y.R, Wu, B.
登録日	2021-12-27
公開日	2022-12-07
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.449 Å)
主引用文献	Vav2 is a novel APP-interacting protein that regulates APP protein level. Sci Rep, 12, 2022

1RLD

SOLID-STATE PHASE TRANSITION IN THE CRYSTAL STRUCTURE OF RIBULOSE 1,5-BIPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE
分子名称:	RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (LARGE CHAIN), RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (SMALL CHAIN)
著者	Zhang, K.Y.J, Eisenberg, D.
登録日	1993-12-10
公開日	1994-04-30
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Solid-state phase transition in the crystal structure of ribulose 1,5-bisphosphate carboxylase/oxygenase. Acta Crystallogr.,Sect.D, 50, 1994

1RLC

CRYSTAL STRUCTURE OF THE UNACTIVATED RIBULOSE 1, 5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE COMPLEXED WITH A TRANSITION STATE ANALOG, 2-CARBOXY-D-ARABINITOL 1,5-BISPHOSPHATE
分子名称:	2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (LARGE CHAIN), RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (SMALL CHAIN)
著者	Zhang, K.Y.J, Cascio, D, Eisenberg, D.
登録日	1993-08-04
公開日	1993-10-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Crystal structure of the unactivated ribulose 1,5-bisphosphate carboxylase/oxygenase complexed with a transition state analog, 2-carboxy-D-arabinitol 1,5-bisphosphate. Protein Sci., 3, 1994

3C4E

Pim-1 Kinase Domain in Complex with 3-aminophenyl-7-azaindole
分子名称:	IMIDAZOLE, N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine, Proto-oncogene serine/threonine-protein kinase Pim-1
著者	Zhang, K.Y.J, Wang, W.
登録日	2008-01-29
公開日	2008-02-26
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.98 Å)
主引用文献	Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity Proc.Natl.Acad.Sci.Usa, 105, 2008

3C4C

B-Raf Kinase in Complex with PLX4720
分子名称:	B-Raf proto-oncogene serine/threonine-protein kinase, N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
著者	Zhang, K.Y.J, Wang, W.
登録日	2008-01-29
公開日	2008-02-26
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.57 Å)
主引用文献	Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity Proc.Natl.Acad.Sci.Usa, 105, 2008

3C4F

FGFR TYROSINE KINASE DOMAIN IN COMPLEX WITH 3-(3-methoxybenzyl)-7-azaindole
分子名称:	3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine, Basic fibroblast growth factor receptor 1
著者	Zhang, K.Y.J, Wang, W.
登録日	2008-01-29
公開日	2008-02-26
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.07 Å)
主引用文献	Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity Proc.Natl.Acad.Sci.Usa, 105, 2008

3ET2

Structure of PPARdelta with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid
分子名称:	1-BUTANOL, 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid, Peroxisome proliferator-activated receptor delta
著者	Zhang, K.Y.J, Wang, W.
登録日	2008-10-06
公開日	2009-02-17
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.24 Å)
主引用文献	Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009

3ET1

Structure of PPARalpha with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid
分子名称:	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid, Peroxisome proliferator-activated receptor alpha, Steroid receptor coactivator 1
著者	Zhang, K.Y.J, Wang, W.
登録日	2008-10-06
公開日	2009-02-17
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009

3ET0

Structure of PPARgamma with 3-(5-Methoxy-1H-indol-3-yl)-propionic acid
分子名称:	3-(5-methoxy-1H-indol-3-yl)propanoic acid, Peroxisome proliferator-activated receptor gamma, alpha-D-glucopyranose
著者	Zhang, K.Y.J, Wang, W.
登録日	2008-10-06
公開日	2009-02-17
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009

3ET3

Structure of PPARgamma with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid
分子名称:	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid, Peroxisome proliferator-activated receptor gamma, Steroid receptor coactivator 1
著者	Zhang, K.Y.J, Wang, W.
登録日	2008-10-06
公開日	2009-02-17
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009

6O6M

The Structure of EgtB (Cabther)
分子名称:	EgtB (Cabther), FE (III) ION, GLYCEROL
著者	Irani, S, Zhang, Y.
登録日	2019-03-07
公開日	2019-07-31
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.506 Å)
主引用文献	Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity. Acs Catalysis, 9, 2019

6OVG

L-Methionine Depletion with an Engineered Human Enzyme Disrupts Prostate Cancer Metabolism
分子名称:	Cystathionine gamma-lyase, SULFATE ION
著者	Yan, W, Irani, S, Zhang, J.
登録日	2019-05-07
公開日	2020-04-22
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.719 Å)
主引用文献	Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proc.Natl.Acad.Sci.USA, 117, 2020

4N8N

Crystal structure of Mycobacterial FtsX extracellular domain
分子名称:	Cell division protein FtsX, POTASSIUM ION
著者	Mavrici, D.
登録日	2013-10-17
公開日	2014-05-28
最終更新日	2017-11-15
実験手法	X-RAY DIFFRACTION (1.874 Å)
主引用文献	Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC. Proc.Natl.Acad.Sci.USA, 111, 2014

4YGX

Crystal Structure of D. melanogaster Ssu72+Symplekin bound to cis peptidomimetic CTD phospho-Ser5 peptide
分子名称:	LD40846p, Symplekin, cis peptidomimetic CTD phospho-Ser5 peptide
著者	Mayfield, J.E, Zhang, Y.
登録日	2015-02-26
公開日	2015-09-16
最終更新日	2015-10-28
実験手法	X-RAY DIFFRACTION (2.95 Å)
主引用文献	Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015

4YH1

Structure of Human Scp1 bound to cis-proline peptidomimetic CTD phospho-Ser5 peptide
分子名称:	A small phosphatase 1, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
著者	Mayfield, J.E, Zhang, Y.
登録日	2015-02-26
公開日	2015-09-16
最終更新日	2015-10-28
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015

4YGY

Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide
分子名称:	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, peptidomimetic CTD phospho-Ser5 peptide
著者	Mayfield, J.E, Zhang, Y.
登録日	2015-02-26
公開日	2015-09-16
最終更新日	2015-10-28
実験手法	X-RAY DIFFRACTION (2.36 Å)
主引用文献	Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015

4ZM9

Crystal structure of circularly permuted human asparaginase-like protein 1
分子名称:	2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CITRATE ANION, ...
著者	Li, W.Z, Zhang, Y.
登録日	2015-05-02
公開日	2016-02-17
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.51 Å)
主引用文献	Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages. Biochemistry, 55, 2016

6BGN

Crystal Structure of 4-Oxalocrotonate Tautomerase After Incubation with 5-Fluoro-2-hydroxy-2,4-pentadienoate
分子名称:	2-hydroxymuconate tautomerase, 5-fluoranyl-2-oxidanylidene-pentanoic acid, GLYCEROL, ...
著者	Zhang, Y, Li, W, Stack, T.
登録日	2017-10-29
公開日	2018-02-21
最終更新日	2019-12-25
実験手法	X-RAY DIFFRACTION (1.51 Å)
主引用文献	Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry, 57, 2018

4N8O

Crystal structure of Mycobacterial FtsX extracellular domain, bromide derivative
分子名称:	BROMIDE ION, Cell division protein FtsX, POTASSIUM ION
著者	Mavrici, D.
登録日	2013-10-17
公開日	2014-05-28
最終更新日	2017-11-15
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC. Proc.Natl.Acad.Sci.USA, 111, 2014

6O6L

The Structure of EgtB(Cabther) in complex with Hercynine
分子名称:	EgtB (Cabther), FE (III) ION, N,N,N-trimethyl-histidine
著者	Irani, S, Zhang, Y.
登録日	2019-03-07
公開日	2019-07-31
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity. Acs Catalysis, 9, 2019

5TIG

CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BrHPD
分子名称:	(3E)-5-hydroxy-2-oxopent-3-enoic acid, 2-hydroxymuconate tautomerase
著者	Zhang, Y, Li, W, Stack, T.
登録日	2016-10-02
公開日	2018-02-21
最終更新日	2019-04-17
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry, 57, 2018

5TT2

Inactive conformation of engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine
分子名称:	Cystathionine gamma-lyase, SULFATE ION
著者	Yan, W, Zhang, Y.
登録日	2016-10-31
公開日	2017-10-11
最終更新日	2019-11-27
実験手法	X-RAY DIFFRACTION (2.949 Å)
主引用文献	Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site. Biochemistry, 56, 2017

5V1X

Carbon Sulfoxide lyase, Egt2 Y134F in complex with its substrate
分子名称:	(1S)-2-{2-[(R)-(2R)-2-amino-2-carboxyethanesulfinyl]-1H-imidazol-4-yl}-1-carboxy-N,N,N-trimethylethan-1-aminium, FORMIC ACID, Hercynylcysteine sulfoxide lyase
著者	Irani, S, Zhang, Y.
登録日	2017-03-02
公開日	2018-03-07
最終更新日	2024-05-15
実験手法	X-RAY DIFFRACTION (2.558 Å)
主引用文献	Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism. Cell Chem Biol, 25, 2018

5UTS

Carbon Sulfoxide lyase, Egt2 in the Ergothioneine biosynthesis pathway
分子名称:	C-S Lyase Egt2, FORMIC ACID
著者	Irani, S, Zhang, Y.
登録日	2017-02-15
公開日	2018-02-21
最終更新日	2019-03-20
実験手法	X-RAY DIFFRACTION (2.303 Å)
主引用文献	Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism. Cell Chem Biol, 25, 2018

7CWS

SARS-CoV-2 Spike Proteins Trimer in Complex with FC05 and H014 Fabs Cocktail
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of FC05 Fab, ...
著者	Wang, L, Wang, X.
登録日	2020-08-31
公開日	2020-12-16
最終更新日	2021-01-13
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	Structure-based development of human antibody cocktails against SARS-CoV-2. Cell Res., 31, 2021

<1 2 3 456 7 >

全ヒット件数:	175
表示件数:	25
表示順	関連性が高い順