8QCX
 
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8DNT
 | | SARS-CoV-2 specific T cell receptor | | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, Nucleoprotein, ... | | 著者 | Gallagher, D.T, Wu, D, Gowthaman, R, Pierce, B.G, Mariuzza, R.A, Weng, N.P. | | 登録日 | 2022-07-11 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Nat Commun, 14, 2023
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8QCY
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8R8T
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7OY2
 | | High resolution structure of cytochrome bd-II oxidase from E. coli | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(2~{E},6~{E},10~{Z},14~{E},18~{E},22~{E},26~{E})-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl]naphthalene-1,4-dione, CARDIOLIPIN, ... | | 著者 | Grund, T.N, Wu, D, Bald, D, Michel, H, Safarian, S. | | 登録日 | 2021-06-23 | | 公開日 | 2021-12-15 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (2.06 Å) | | 主引用文献 | Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
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6KUX
 | | Crystal structures of the alpha2A adrenergic receptor in complex with an antagonist RSC. | | 分子名称: | (8~{a}~{R},12~{a}~{S},13~{a}~{S})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridine, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Qu, L, Zhou, Q.T, Wu, D, Zhao, S.W. | | 登録日 | 2019-09-02 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of the alpha2A adrenergic receptor in complex with an antagonist RSC.
To Be Published
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3DOO
 | | Crystal structure of shikimate dehydrogenase from Staphylococcus epidermidis complexed with shikimate | | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, Shikimate dehydrogenase | | 著者 | Han, C, Hu, T, Wu, D, Zhou, J, Shen, X, Qu, D, Jiang, H. | | 登録日 | 2008-07-05 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis
Febs J., 276, 2009
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3DON
 | | Crystal structure of shikimate dehydrogenase from Staphylococcus epidermidis | | 分子名称: | GLYCEROL, Shikimate dehydrogenase | | 著者 | Han, C, Hu, T, Wu, D, Zhou, J, Shen, X, Qu, D, Jiang, H. | | 登録日 | 2008-07-05 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis
Febs J., 276, 2009
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6LZL
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine | | 分子名称: | (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | | 著者 | Liu, Z.H, Wu, D, Lu, W.Q, Huang, J. | | 登録日 | 2020-02-19 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine
To Be Published
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8QD0
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8QCZ
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3CF8
 | | Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with quercetin | | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, BENZAMIDINE, ... | | 著者 | Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H. | | 登録日 | 2008-03-03 | | 公開日 | 2008-12-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008
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3CF9
 | | Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with apigenin | | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, BENZAMIDINE, ... | | 著者 | Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H. | | 登録日 | 2008-03-03 | | 公開日 | 2008-12-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008
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7NKZ
 | | Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution | | 分子名称: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, HEME B/C, MENAQUINONE-9, ... | | 著者 | Safarian, S, Wu, D, Krause, K.L, Michel, H. | | 登録日 | 2021-02-19 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Nat Commun, 12, 2021
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6O7V
 | | Saccharomyces cerevisiae V-ATPase Stv1-V1VO State 1 | | 分子名称: | Putative protein YPR170W-B, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Vasanthakumar, T, Bueler, S.A, Wu, D, Beilsten-Edmands, V, Robinson, C.V, Rubinstein, J.L. | | 登録日 | 2019-03-08 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structural comparison of the vacuolar and Golgi V-ATPases fromSaccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6O7T
 | | Saccharomyces cerevisiae V-ATPase Vph1-VO | | 分子名称: | Putative protein YPR170W-B, V-type proton ATPase subunit a, vacuolar isoform, ... | | 著者 | Vasanthakumar, T, Bueler, S.A, Wu, D, Beilsten-Edmands, V, Robinson, C.V, Rubinstein, J.L. | | 登録日 | 2019-03-08 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural comparison of the vacuolar and Golgi V-ATPases fromSaccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6O7W
 | | Saccharomyces cerevisiae V-ATPase Stv1-V1VO State 2 | | 分子名称: | Putative protein YPR170W-B, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Vasanthakumar, T, Bueler, S.A, Wu, D, Beilsten-Edmands, V, Robinson, C.V, Rubinstein, J.L. | | 登録日 | 2019-03-08 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Structural comparison of the vacuolar and Golgi V-ATPases fromSaccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6O7U
 | | Saccharomyces cerevisiae V-ATPase Stv1-VO | | 分子名称: | Putative protein YPR170W-B, V-type proton ATPase subunit a, Golgi isoform, ... | | 著者 | Vasanthakumar, T, Bueler, S.A, Wu, D, Beilsten-Edmands, V, Robinson, C.V, Rubinstein, J.L. | | 登録日 | 2019-03-08 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural comparison of the vacuolar and Golgi V-ATPases fromSaccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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2AKR
 | | Structural basis of sulfatide presentation by mouse CD1d | | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zajonc, D.M, Halder, R, Wu, D, Maricic, I, Roy, K, Wong, C.-H, Kumar, V, Wilson, I.A. | | 登録日 | 2005-08-03 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity
J.Exp.Med., 202, 2005
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6IJI
 | | Crystal structure of PDE10 in complex with inhibitor 2b | | 分子名称: | 2-{2-[5-methyl-1-(pyridin-4-yl)-1H-benzimidazol-2-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione, MAGNESIUM ION, ZINC ION, ... | | 著者 | Huang, Y.Y, Yu, Y.F, Zhang, C, Wu, D, Wu, Y, Luo, H.B. | | 登録日 | 2018-10-10 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
J. Med. Chem., 62, 2019
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6IJH
 | | Crystal structure of PDE10 in complex with inhibitor AF-399/14387019 | | 分子名称: | 2-[2-(4-phenyl-5-sulfanylidene-4,5-dihydro-1H-1,2,4-triazol-3-yl)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, MAGNESIUM ION, ZINC ION, ... | | 著者 | Huang, Y.Y, Yu, Y.F, Zhang, C, Wu, D, Wu, Y, Luo, H.B. | | 登録日 | 2018-10-10 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
J. Med. Chem., 62, 2019
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3C5Q
 | | Crystal structure of diaminopimelate decarboxylase (I148L mutant) from Helicobacter pylori complexed with L-lysine | | 分子名称: | Diaminopimelate decarboxylase, GLYCEROL, LYSINE, ... | | 著者 | Hu, T, Wu, D, Jiang, H, Shen, X. | | 登録日 | 2008-02-01 | | 公開日 | 2008-05-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of diaminopimelate decarboxylase from Helicobacter pylori
To be Published
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4REW
 | | Crystal structure of the non-phosphorylated human alpha1 beta2 gamma1 holo-AMPK complex | | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | | 著者 | Zhou, X.E, Ke, J, Li, X, Wang, L, Gu, X, de Waal, P.W, Tan, M.H.E, Wang, D, Wu, D, Xu, H.E, Melcher, K. | | 登録日 | 2014-09-24 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (4.58 Å) | | 主引用文献 | Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
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5OEV
 | | The structure of a glutathione synthetase like-effector (GSS22) from Globodera pallida in apoform. | | 分子名称: | Glutathione synthetase-like effector 22 (Gpa-GSS22-apo) | | 著者 | Lilley, C.J, Maqbool, A, Wu, D, Yusup, H.B, Jones, L.M, Birch, P.R.J, Banfield, M.J, Urwin, P.E, Eves-van den Akker, S. | | 登録日 | 2017-07-10 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Effector gene birth in plant parasitic nematodes: Neofunctionalization of a housekeeping glutathione synthetase gene.
PLoS Genet., 14, 2018
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5OEU
 | | The structure of a glutathione synthetase like-effector (GSS22) from Globodera pallida in ADP-bound closed conformation. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Glutathione synthetase-like effector 22 (Gpa-GSS22-closed), MAGNESIUM ION | | 著者 | Lilley, C.J, Maqbool, A, Wu, D, Yusup, H.B, Jones, L.M, Birch, P.R.J, Banfield, M.J, Urwin, P.E, Eves-van den Akker, S. | | 登録日 | 2017-07-10 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Effector gene birth in plant parasitic nematodes: Neofunctionalization of a housekeeping glutathione synthetase gene.
PLoS Genet., 14, 2018
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