8QD0

Cryo-EM structure of the inward-facing choline-bound FLVCR2

Summary for 8QD0

Entry DOI	10.2210/pdb8qd0/pdb
Related	8QCX
EMDB information	18339
Descriptor	Heme transporter FLVCR2, CHOLINE ION (2 entities in total)
Functional Keywords	mfs, choline transport, human transporter, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	58381.26
Authors	Weng, T.-H.,Wu, D.,Safarian, S. (deposition date: 2023-08-28, release date: 2024-04-17, Last modification date: 2024-06-19)
Primary citation	Ri, K.,Weng, T.H.,Claveras Cabezudo, A.,Josting, W.,Zhang, Y.,Bazzone, A.,Leong, N.C.P.,Welsch, S.,Doty, R.T.,Gursu, G.,Lim, T.J.Y.,Schmidt, S.L.,Abkowitz, J.L.,Hummer, G.,Wu, D.,Nguyen, L.N.,Safarian, S. Molecular mechanism of choline and ethanolamine transport in humans. Nature, 630:501-508, 2024 Cited by PubMed: 38778100 DOI: 10.1038/s41586-024-07444-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation