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6KUX

Crystal structures of the alpha2A adrenergic receptor in complex with an antagonist RSC.

Summary for 6KUX
Entry DOI10.2210/pdb6kux/pdb
Descriptoralpha2A adrenergic receptor, (8~{a}~{R},12~{a}~{S},13~{a}~{S})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridine, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywordsalpha2a adrenergic receptor, antagonist, gpcr, signaling protein
Biological sourceHomo sapiens
Total number of polymer chains1
Total formula weight45857.57
Authors
Qu, L.,Zhou, Q.T.,Wu, D.,Zhao, S.W. (deposition date: 2019-09-02, release date: 2019-12-04, Last modification date: 2023-11-22)
Primary citationQu, L.,Zhou, Q.T.,Wu, D.,Zhao, S.W.
Crystal structures of the alpha2A adrenergic receptor in complex with an antagonist RSC.
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

217705

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