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6KUX

Crystal structures of the alpha2A adrenergic receptor in complex with an antagonist RSC.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
alpha2A adrenergic receptorpolymer39544490.91Pfam (PF00001)
UniProt (by SIFTS) (P08913)
Homo sapiens
2B
(A)
(8~{a}~{R},12~{a}~{S},13~{a}~{S})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridinenon-polymer364.51Chemie (E3F)
3C, D, E, F, G
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.15Chemie (PEG)
4H
(A)
OLEIC ACIDnon-polymer282.51Chemie (OLA)
5I
(A)
CITRATE ANIONnon-polymer189.11Chemie (FLC)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight44490.9
Non-Polymers*Number of molecules8
Total formula weight1366.7
All*Total formula weight45857.6
*Water molecules are not included.

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PDB entries from 2026-01-28

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