1JAI
| H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MANGANESE | 分子名称: | C-HA-RAS, MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | 著者 | Schweins, T, Scheffzek, K, Assheuer, R, Wittinghofer, A. | 登録日 | 1996-12-15 | 公開日 | 1997-07-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+. J.Mol.Biol., 266, 1997
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4JHP
| The crystal structure of the RPGR RCC1-like domain in complex with PDE6D | 分子名称: | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, X-linked retinitis pigmentosa GTPase regulator | 著者 | Waetzlich, D, Vetter, I, Wittinghofer, A, Ismail, S. | 登録日 | 2013-03-05 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo. Embo Rep., 14, 2013
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4M9Q
| Crystal structure of C-terminally truncated Arl13B from Chlamydomonas rheinhardtii bound to GppNHp | 分子名称: | ARF-like GTPase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Miertzschke, M, Koerner, C, Spoerner, M, Wittinghofer, A. | 登録日 | 2013-08-15 | 公開日 | 2013-11-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into the small G-protein Arl13B and implications for Joubert syndrome. Biochem.J., 457, 2014
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4JHN
| The crystal structure of the RPGR RCC1-like domain | 分子名称: | X-linked retinitis pigmentosa GTPase regulator | 著者 | Waetzlich, D, Vetter, I, Wittinghofer, A, Ismail, S. | 登録日 | 2013-03-05 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo. Embo Rep., 14, 2013
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1SRQ
| Crystal Structure of the Rap1GAP catalytic domain | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GTPase-activating protein 1, SULFATE ION | 著者 | Daumke, O, Weyand, M, Chakrabarti, P.P, Vetter, I.R, Wittinghofer, A. | 登録日 | 2004-03-23 | 公開日 | 2004-05-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The GTPase activating protein Rap1GAP uses a catalytic asparagine Nature, 429, 2004
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1I2M
| RAN-RCC1-SO4 COMPLEX | 分子名称: | GTP-BINDING NUCLEAR PROTEIN RAN, REGULATOR OF CHROMOSOME CONDENSATION 1, SULFATE ION | 著者 | Renault, L, Kuhlmann, J, Henkel, A, Wittinghofer, A. | 登録日 | 2001-02-11 | 公開日 | 2001-05-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell(Cambridge,Mass.), 105, 2001
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1IBR
| COMPLEX OF RAN WITH IMPORTIN BETA | 分子名称: | GTP-binding nuclear protein RAN, Importin beta-1 subunit, MAGNESIUM ION, ... | 著者 | Vetter, I.R, Arndt, A, Kutay, U, Goerlich, D, Wittinghofer, A. | 登録日 | 1999-05-14 | 公開日 | 1999-06-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural view of the Ran-Importin beta interaction at 2.3 A resolution Cell(Cambridge,Mass.), 97, 1999
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2O98
| Structure of the 14-3-3 / H+-ATPase plant complex | 分子名称: | 14-3-3-like protein C, FUSICOCCIN, Plasma membrane H+ ATPase, ... | 著者 | Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C. | 登録日 | 2006-12-13 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy Mol.Cell, 25, 2007
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1YE8
| Crystal Structure of THEP1 from the hyperthermophile Aquifex aeolicus | 分子名称: | Hypothetical UPF0334 kinase-like protein AQ_1292, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Rossbach, M, Daumke, O, Klinger, C, Wittinghofer, A, Kaufmann, M. | 登録日 | 2004-12-28 | 公開日 | 2005-03-29 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold BMC Struct.Biol., 5, 2005
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2QA5
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1O9F
| Structural view of a fungal toxin acting on a 14-3-3 regulatory complex | 分子名称: | 14-3-3-LIKE PROTEIN C, FUSICOCCIN, PLASMA MEMBRANE H+ ATPASE | 著者 | Wurtele, M, Jelich-Ottmann, C, Wittinghofer, A, Oecking, C. | 登録日 | 2002-12-12 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural View of a Fungal Toxin Acting on a 14-3-3 Regulatory Complex Embo J., 22, 2003
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1USE
| human VASP tetramerisation domain | 分子名称: | VASODILATOR-STIMULATED PHOSPHOPROTEIN | 著者 | Kuhnel, K, Jarchau, T, Wolf, E, Schlichting, I, Walter, U, Wittinghofer, A, Strelkov, S.V. | 登録日 | 2003-11-21 | 公開日 | 2004-11-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The Vasp Tetramerization Domain is a Right-Handed Coiled Coil Based on a 15-Residue Repeat Proc.Natl.Acad.Sci.USA, 101, 2004
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1USD
| human VASP tetramerisation domain L352M | 分子名称: | VASODILATOR-STIMULATED PHOSPHOPROTEIN | 著者 | Kuhnel, K, Jarchau, T, Wolf, E, Schlichting, I, Walter, U, Wittinghofer, A, Strelkov, S.V. | 登録日 | 2003-11-21 | 公開日 | 2004-11-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Vasp Tetramerization Domain is a Right-Handed Coiled Coil Based on a 15-Residue Repeat Proc.Natl.Acad.Sci.USA, 101, 2004
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3EG5
| Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP | 分子名称: | Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Lammers, M, Meyer, S, Kuehlmann, D, Wittinghofer, A. | 登録日 | 2008-09-10 | 公開日 | 2008-10-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Specificity of Interactions between mDia Isoforms and Rho Proteins J.Biol.Chem., 283, 2008
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3E6Y
| Structure of 14-3-3 in complex with the differentiation-inducing agent Cotylenin A | 分子名称: | 14-3-3-like protein C, CHLORIDE ION, Cotylenin A, ... | 著者 | Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C. | 登録日 | 2008-08-17 | 公開日 | 2009-03-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A J.Mol.Biol., 386, 2009
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2BX6
| Crystal Structure of the human Retinitis Pigmentosa protein 2 (RP2) | 分子名称: | SULFATE ION, XRP2 PROTEIN | 著者 | Kuhnel, K, Veltel, S, Schlichting, I, Wittinghofer, A. | 登録日 | 2005-07-24 | 公開日 | 2006-01-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the Human Retinitis Pigmentosa 2 Protein and its Interaction with Arl3 Structure, 14, 2006
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1A4R
| G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM | 分子名称: | AMINOPHOSPHONIC ACID-GUANYLATE ESTER, G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Rudolph, M.G, Vetter, I.R, Wittinghofer, A. | 登録日 | 1998-02-02 | 公開日 | 1999-03-02 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal. Protein Sci., 8, 1999
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1DG3
| STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM | 分子名称: | PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1) | 著者 | Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | 登録日 | 1999-11-23 | 公開日 | 2000-10-11 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. Nature, 403, 2000
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3FTQ
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1A12
| REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN | 分子名称: | REGULATOR OF CHROMOSOME CONDENSATION 1 | 著者 | Renault, L, Nassar, N, Vetter, I, Becker, J, Roth, M, Wittinghofer, A. | 登録日 | 1997-12-19 | 公開日 | 1999-01-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller. Nature, 392, 1998
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1O9E
| Structural view of a fungal toxin acting on a 14-3-3 regulatory complex | 分子名称: | 14-3-3-LIKE PROTEIN C, CITRATE ANION, FUSICOCCIN | 著者 | Wurtele, M, Jelich-Ottmann, C, Wittinghofer, A, Oecking, C. | 登録日 | 2002-12-12 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural View of a Fungal Toxin Acting on a 14-3-3 Regulatory Complex Embo J., 22, 2003
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1O9D
| Structural view of a fungal toxin acting on a 14-3-3 regulatory complex | 分子名称: | 14-3-3-LIKE PROTEIN C, PLASMA MEMBRANE H+ ATPASE | 著者 | Wurtele, M, Jelich-Ottmann, C, Wittinghofer, A, Oecking, C. | 登録日 | 2002-12-12 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural View of a Fungal Toxin Acting on a 14-3-3 Regulatory Complex Embo J., 22, 2003
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1O9C
| Structural view of a fungal toxin acting on a 14-3-3 regulatory complex | 分子名称: | 14-3-3-LIKE PROTEIN C, CHLORIDE ION, CITRATE ANION | 著者 | Wurtele, M, Jelich-Ottmann, C, Wittinghofer, A, Oecking, C. | 登録日 | 2002-12-12 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural View of a Fungal Toxin Acting on a 14-3-3 Regulatory Complex Embo J., 22, 2003
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3T1Q
| MglA bound to GppNHp in complex with MglB | 分子名称: | Gliding protein MglB, Gliding protein mglA, MAGNESIUM ION, ... | 著者 | Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A. | 登録日 | 2011-07-22 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity. Embo J., 30, 2011
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3T1X
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