3E6Y
Structure of 14-3-3 in complex with the differentiation-inducing agent Cotylenin A
Summary for 3E6Y
Entry DOI | 10.2210/pdb3e6y/pdb |
Descriptor | 14-3-3-like protein C, H+-ATPase phosphopeptide QSYpTV, Cotylenin A, ... (5 entities in total) |
Functional Keywords | adapter protein, signaling protein |
Biological source | Nicotiana tabacum (American tobacco,tobacco) More |
Total number of polymer chains | 4 |
Total formula weight | 61494.17 |
Authors | Ottmann, C.,Weyand, M.,Wittinghofer, A.,Oecking, C. (deposition date: 2008-08-17, release date: 2009-03-10, Last modification date: 2023-08-30) |
Primary citation | Ottmann, C.,Weyand, M.,Sassa, T.,Inoue, T.,Kato, N.,Wittinghofer, A.,Oecking, C. A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A J.Mol.Biol., 386:913-919, 2009 Cited by PubMed: 19244612PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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