8ITA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ita by Molmil](/molmil-images/mine/8ita) | A reversible glycosyltransferase of tectorigenin - Bc7OUGT complexed with UDP and tectorigenin | 分子名称: | 3-(4-hydroxyphenyl)-6-methoxy-5,7-bis(oxidanyl)chromen-4-one, Bc7OUGT, URIDINE-5'-DIPHOSPHATE | 著者 | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | 登録日 | 2023-03-22 | 公開日 | 2023-08-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence. Plant Biotechnol J, 21, 2023
|
|
8P8T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p8t by Molmil](/molmil-images/mine/8p8t) | Ex vivo Ym2 crystal structure | 分子名称: | Chitinase-like protein 4, GLYCEROL | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N. | 登録日 | 2023-06-02 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Ym1 protein crystals promote type 2 immunity. Elife, 12, 2024
|
|
8P8Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p8q by Molmil](/molmil-images/mine/8p8q) | Recombinant Ym1 crystal structure | 分子名称: | ACETATE ION, Chitinase-like protein 3, GLYCEROL | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Aegerter, H, Smole, U, Savvides, S.N, Lambrecht, B.N. | 登録日 | 2023-06-02 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | Ym1 protein crystals promote type 2 immunity. Elife, 12, 2024
|
|
8P8S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p8s by Molmil](/molmil-images/mine/8p8s) | Recombinant Ym2 crystal structure | 分子名称: | 1,2-ETHANEDIOL, Chitinase-like protein 4 | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, A, Savvides, S.N, Lambrecht, B.N. | 登録日 | 2023-06-02 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Ym1 protein crystals promote type 2 immunity. Elife, 12, 2024
|
|
8P8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p8r by Molmil](/molmil-images/mine/8p8r) | Ex vivo Ym1 crystal structure | 分子名称: | 1,2-ETHANEDIOL, Chitinase-like protein 3 | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N. | 登録日 | 2023-06-02 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Ym1 protein crystals promote type 2 immunity. Elife, 12, 2024
|
|
6QCL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qcl by Molmil](/molmil-images/mine/6qcl) | |
6QFB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qfb by Molmil](/molmil-images/mine/6qfb) | |
8U18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u18 by Molmil](/molmil-images/mine/8u18) | Cryo-EM structure of murine Thrombopoietin receptor ectodomain in complex with Tpo | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombopoietin, Thrombopoietin receptor,GCN4 isoform 1, ... | 著者 | Sarson-Lawrence, K.S, Hardy, J.M, Leis, A, Babon, J.J, Kershaw, N.J. | 登録日 | 2023-08-30 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin. Nat Commun, 15, 2024
|
|
6GLX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glx by Molmil](/molmil-images/mine/6glx) | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8 | 分子名称: | Fab 4E8 - Heavy chain, Fab 4E8 - Light chain, Galectin-10 | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | 登録日 | 2018-05-23 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.396 Å) | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
|
|
7AQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7aqe by Molmil](/molmil-images/mine/7aqe) | Structure of SARS-CoV-2 Main Protease bound to UNC-2327 | 分子名称: | 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Guenther, S, Reinke, P, Meents, A. | 登録日 | 2020-10-21 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
|
|
7Z3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z3r by Molmil](/molmil-images/mine/7z3r) | Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A. | 登録日 | 2022-03-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.951 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
|
|
7Z3P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z3p by Molmil](/molmil-images/mine/7z3p) | Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution. | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ... | 著者 | Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K. | 登録日 | 2022-03-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.943 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
|
|
7Z3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z3q by Molmil](/molmil-images/mine/7z3q) | Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution. | 分子名称: | Leptin, Leptin receptor | 著者 | Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N. | 登録日 | 2022-03-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.617 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
|
|
8BEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bey by Molmil](/molmil-images/mine/8bey) | Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein at pH 7 | 分子名称: | Cry49Aa protein | 著者 | Williamson, L.J, Rizkallah, P.J, Berry, C, Oberthur, D, Galchenkova, M, Yefanov, O, Bean, R. | 登録日 | 2022-10-22 | 公開日 | 2023-11-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8BEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bex by Molmil](/molmil-images/mine/8bex) | Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein at pH 3 | 分子名称: | Cry49Aa protein | 著者 | Williamson, L.J, Rizkallah, P.J, Berry, C, Oberthur, D, Galchenkova, M, Yefanov, O, Bean, R. | 登録日 | 2022-10-22 | 公開日 | 2023-11-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8BEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bez by Molmil](/molmil-images/mine/8bez) | Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein at pH 11 | 分子名称: | Cry49Aa protein | 著者 | Williamson, L.J, Rizkallah, P.J, Berry, C, Oberthur, D, Galchenkova, M, Yefanov, O, Bean, R. | 登録日 | 2022-10-22 | 公開日 | 2023-11-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8UWF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uwf by Molmil](/molmil-images/mine/8uwf) | NMR structure of the funnel-web spider toxin Hc3a | 分子名称: | Pi-Hexatoxin-Hc1b_1 | 著者 | Budusan, E, Payne, C.D, Gonzalez, T.I, Clark, R.J, Rosengren, K.J, Rash, L.D, Cristofori-Armstrong, B. | 登録日 | 2023-11-06 | 公開日 | 2024-03-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation. Biochem Pharmacol, 2024
|
|
6GKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gks by Molmil](/molmil-images/mine/6gks) | |
6GKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gkq by Molmil](/molmil-images/mine/6gkq) | |
6GLW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glw by Molmil](/molmil-images/mine/6glw) | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11 | 分子名称: | ACETATE ION, Fab 1D11 - Heavy chain, Fab 1D11 - Light chain, ... | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | 登録日 | 2018-05-23 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
|
|
6GKT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gkt by Molmil](/molmil-images/mine/6gkt) | X-ray structure of a non-autocrystallizing galectin-10 variant, Gal10-Tyr69Glu | 分子名称: | Galectin-10, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | 登録日 | 2018-05-21 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
|
|
6GKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gku by Molmil](/molmil-images/mine/6gku) | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5 | 分子名称: | CALCIUM ION, Fab 6F5 - Heavy Chain, Fab 6F5 - Light chain, ... | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | 登録日 | 2018-05-21 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
|
|
3HKY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hky by Molmil](/molmil-images/mine/3hky) | HCV NS5B polymerase genotype 1b in complex with 1,5 benzodiazepine 6 | 分子名称: | (11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, CHLORIDE ION, RNA-directed RNA polymerase, ... | 著者 | Nyanguile, O, De Bondt, H.L. | 登録日 | 2009-05-26 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus J.Virol., 84, 2010
|
|
3HKW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hkw by Molmil](/molmil-images/mine/3hkw) | HCV NS5B genotype 1a in complex with 1,5 benzodiazepine inhibitor 6 | 分子名称: | (11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, GLYCEROL, NS5B RNA-dependent RNA polymerase, ... | 著者 | Nyanguile, O, De Bondt, H.L. | 登録日 | 2009-05-26 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | 1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus J.Virol., 84, 2010
|
|
8F0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f0k by Molmil](/molmil-images/mine/8f0k) | Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 | 分子名称: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Cao, J, Sexton, P.M, Wootten, D.L. | 登録日 | 2022-11-03 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | 主引用文献 | Structural insight into selectivity of amylin and calcitonin receptor agonists. Nat.Chem.Biol., 20, 2024
|
|